Original Article: Daraxonrasib or Chemotherapy in Previously Treated Metastatic Pancreatic Cancer (phase 3 RASolute 302 trial) https://t.co/y4G27hfORg
#ASCO26 | @ASCO
Cheers, chills, and a standing ovation when RASolute 302 showed unprecedented survival on daraxonrasib for patients with progressive pancreatic cancer
Seldom do you sense you’re witnessing a historic moment in cancer care but this feels like ras targeting has arrived
#ASCO26
#PancreaticCancer remains a challenge. Targeting #KRAS was a key step—but responses are often temporary. New @theNCI-supported work identifies a protein that may drive resistance, opening a path to extend treatment benefit in pancreatic and other cancers https://t.co/HAeCYUMuYW
Proud to share our @NaturePortfolio research article: "RASH3D19 as a mediator of RAS pathway activation through a positive feedback loop in KRAS-mutant cancer", now out in Nature Cell Biology.
Read it here: https://t.co/iKHqCS0qJU
https://t.co/fXid5iXPyU
Congratulations to Subrata Sen & team
@MDAndersonNews for their @NatureCellBio paper:
RASH3D19 mediates RAS activation through a positive feedback loop in KRAS-mutant cancer
https://t.co/EIa1C4TPPi
In this @BrJCancer study, scientists from @MDAndersonNews discover that epigenetic activation of 🧦 SOX11 drives 🚙 recurrence of ductal carcinoma in-situ (DCIS) and progression 📈 to invasive cancer.
😎 Check it out: https://t.co/N8gmQ2DRWT
Examining the role of eEF1A2 in cancer, researchers at @MDAndersonNews find the factor normally interacts with the tumor suppressor #PTEN to repress the #CellCycle and degrade Aurora-A, but that the latter is more abundant in #BreastCancer tissues. https://t.co/H2uQHjaCc6
A riddle for scientists: what is (1) better than publishing in Nature, (2) more evil than reviewer 2, (3) the postdocs have it, (4) the Nobel prize winners need it, and (5) if you publish it you perish?
Calling all coffee enthusiasts! Exciting research reveals how caffeine influences #intestinal tumor initiation. Interested in learning more? Click the link ➡️ https://t.co/sqcFBDHSb4
Fascinating talk from @HansClevers on identifying pks E. Coli mutational signatures in intestinal organoid cultures. Elegant work and beautiful animations alongside. #AACR22
Augmented lipocalin-2 is a molecular feature of COPD-associated LUAD and counteracts LUAD development by maintaining anti-tumor immunity.
https://t.co/JZBSfCDG6r
#lungcancer#COPD#EndCancer@humam_kadara @AnsamSinjab