Our researchers @EdinUni_IGC@uniofedinburgh have discovered that aggressive bowel cancer cells are able to "shapeshift" to mimic skin cells to spread around the body, opening the door to new treatments to prevent cancer becoming harder to treat @myantlab@CR_UK Image credit: Aslihan Bastem Akan
Excited and proud to share our latest paper describing how the loss of colonic epithelial identity and the emergence of highly plastic states act as key driver of CRC metastasis. Grateful to everyone who contributed to this work!
Excited to share our new study led by @weepatri published today in @Nature.
In this project, we identified loss of colonic identity as a key step enabling multilineage plasticity and metastasis in colorectal cancer…
https://t.co/q828iKE2Xp
Delighted to share the most recent work from our lab where we identify a role for DOCK2-loss mediated immune dysfunction in IBD-associated colorectal cancer. Great work @amd_churchhouse !
https://t.co/Zgtm0kfOoz
Paper 🚨! Ecstatic, proud, grateful …Years of dedication from the whole lab, with the exceptional @djkloosterman and the one of a kind #JohannaErbani at its helm. What a journey all the way to @CellCellPress! How did it start (& end)? A 🧵1/n
https://t.co/d1SPgjFRDr
Our latest manuscript on a new cell cycle dependent control of dna repair. Started from a high resolution crispr screen of #ubiquitin system after IR: check table S2!
Also substrates of cyclin f through motif search!
https://t.co/foGAoXwwu7
☀️We are looking forward to welcoming all our speakers and delegates to Glasgow later today for our 25th Beatson International Cancer Conference!
🔍Keep an eye on our page for updates throughout the conference
#BICC2024
A two year post doc position is available in my lab in Milan to work on colorectal cancer organoids. DM me directly for discussing if interested.
https://t.co/OgSWA4BB3T
Please RT.
New in @NatureComms from @owen_sansom & team @CRUK_SI
KRAS allelic imbalance drives tumour initiation yet suppresses metastasis in #ColorectalCancer in vivo
https://t.co/f3TqouXCeS
The status of wild type KRAS is now even more important because of therapeutic ramifications.
Check out our recent review on cell plasticity! @myantlab
Thanks to @FrontCellDevBio
for having an efficient editorial process.
Be like water, my cells: cell plasticity and the art of transformation https://t.co/hnK6GsKEut
We’re awarding up to £123m over 7 years to the Cancer Research UK Scotland Institute (formerly known as the Beatson Institute) – congratulations! 🎉
This will support #DiscoveryResearch & cancer types impacting Scotland’s population🧵 [1/3]
👉 https://t.co/mTsix5jcZU
@CRUK_BI
If you are motivated and interested by protein synthesis and cancer stem cells, come and join us !👇! We have a PhD student position opened (FPI contract) ! Please RT @UniBarcelona@idibell_cat
1/ Extremely happy to be able to share our latest stories on the maturation of the intestinal epithelium in same issue of Science Advances. These two stories started their independent life 5 years ago by extremely talented postdocs and students in my team.
Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent immune response against a distant tumor. @yerinchen led the charge w/ help from @DjenetBousbaine, @VeinbachsA, @BelkaidLab. @ScienceMagazine 1/26
https://t.co/bgW3C7CJgh