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Hiding out-of-sight on our produce, pipes, and even teeth are tiny bacterial cells enmeshed within a sticky web. These microbial clusters—known as biofilms—are more resistant to antibiotics and other weapons.
Researchers have discovered another surprising way they survive: ejecting some of their cells as if they were escape pods jettisoned from a doomed sci-fi spaceship, researchers report.
Learn more: https://t.co/55VNDIowbw
Online now!✨Mu, Barthez, Feng, Chen, Wang et al report that trained immunity links hematopoietic stem cell aging to age-associated inflammation https://t.co/lvuDNinhT8
The FDA’s drive to reduce animal testing in drug development has coincided with a boom in AI-powered biosimulation techniques such as multi-agent virtual scientists and digital twins, while organoids and other mature methods embrace AI to ramp up predictive power https://t.co/r04a9Ykqkb
Stimulating a nerve in the ear may alleviate lung inflammation in mice.
Based on these findings, researchers are designing a clinical trial to test a novel device for treating asthma.
Learn more in Immunity: https://t.co/OlySGQCHfs
Brian Kim & colleagues
@immunitycp
What do cancer cells eat? That exact question is the focus of the lab of MSK biologist Dr. Lydia Finley.
At its most fundamental level, cancer is a disease of cells doing things they’re not supposed to do, she says. Dr. Finley and her fellow researchers study cell metabolism, aka how cells convert nutrients into the various molecules that they need to function.
“In simple terms, it’s how cells use food to grow,” she says. “And without access to the right food, cancer cells won’t be able to survive.”
By shedding new light on fundamental biology, the researchers aim to find new strategies that could work against cancer.
“Many of the drugs we use against cancer target fundamental processes in cells that have gone haywire — affecting how they function, how they grow, how they stay alive,” Dr. Finley says. “So we have to know, in great detail, how these processes work if we want to develop new therapies.”
Read more: https://t.co/FY5GtZshui