WesElyMD

Husband & Dad. ICU Doc. Vanderbilt. @CIBScenter studies Covid & Long Covid, ICU Survivorship, PICS, Dementia, Delirium. Tweets my own. Still learning.

[WesElyMD @WesElyMD]

1/🧵 Beauty in simplicity

For too long in life, I thought success was about climbing in the 🌎’s eyes…higher, better, farther. My physician wife & I are “new parents” to my 58 y/o brother w #DownSyndrome & he’s giving me all kinds of new understanding of what matters.

#COVID

[NEJM @NEJM]

Sometimes, as patients near the end of life, eliciting and fulfilling a simple wish can lead to acceptance and a peaceful death — a lesson absorbed by a physician during a week of ice cream. Read the Perspective essay by Biren B. Kamdar, MD, MHS: https://t.co/C3O32sA3Iz

[WesElyMD @WesElyMD]

@KristinaRevay That’s a great question. Many patients w Long COVID do not have viral persistence though some of course do. We are monitoring for this w our biorepository data.

[WesElyMD @WesElyMD]

@FilmandTVMania Yes! Stay tuned!

[WesElyMD @WesElyMD]

We have equipoise about the trial and never know what the answers will be. The most important thing is that we think we’ve designed a trial that will determine the truth and then we will understand the disease state better and be able to move forward to help others, whether this is the right treatment or not.

[WesElyMD @WesElyMD]

@PhotonTurtle I agree. We will be monitoring a half a year off of study drug to see the effects down the line on the lives and symptoms in these people who give up themselves so generously to help us learn

[WesElyMD @WesElyMD]

@Morgs6942 Hope so someday, and we will follow the science. Thanks for this wish list.

[CIBS Center @CIBScenter]

🌟 Join us in the search for answers to Long COVID

The REVERSE-LC Study is enrolling in:
📍 Nashville, TN (@VUMChealth)
📍 Atlanta, GA (@EmoryMedicine)
📍 Minneapolis, MN (@umn_dom)
📍 San Francisco, CA (@UCSF)

👉 Learn more and fill out an interest form here: https://t.co/oWADXU7oA7

#longcovid @WesElyMD @MichaelPelusoMD @BramanteCarolyn @vmarconi2

[Heidi Engel, PT, DPT @HeidiEngel4]

LISTEN & share- The reasons to awaken your #ICU patients within HOURS of intubation ⁦@icurehab⁩ ⁦@DrDaleNeedham⁩ ⁦@WesElyMD⁩ ⁦@NydahlPeter⁩ ⁦@tchen383⁩ ⁦@ICUsteps⁩ ⁦⁩ ⁦@SCCM⁩ ⁦ https://t.co/jwdCXmEp5g

[Michael Peluso, MD @MichaelPelusoMD]

Proud to have been a part of this @polybioRF effort to describe the path forward for #LongCOVID trials targeting SARS-CoV-2 persistence. We need a robust biomarker development program and to launch more trials to rigorously test treatments that target these pathways now.

[Matthew Schrag @schrag_matthew]

Does this look right to you?
Let me take you down a rabbit hole to illustrate how a network of interlacing problems in Alzheimer’s disease research ethics impacts our progress on this disease.

[Amy Proal, PhD @microbeminded2]

Our new Viewpoint is out! We draw from treatment strategies in HIV, Hep C & other infections, to detail key considerations for #LongCovid clinical trials targeting persistent #SARS-CoV-2. These include combination trials of drugs that target both the virus and the immune system: https://t.co/6aFYcPPNi4

[charlos @loscharlos]

This is going viral because everyone feels this way — this is not hyperbolic “everyone has #LongCovid” — but we need to quickly wake up to the reality that the amount of people going through it, but don’t know what it is — is actually quite enormous.

[emma @emma_____weaver]

i miss having a sharper brain. idk how to fix it. my attention span sucks, it’s hard for me to read books, my memory is horrible and it’s hard to retain information, i miss reading but i literally can’t read. I feel so stupid? what do i do

[Eric Topol @EricTopol]

The Covid pandemic suppressed Flu.
A new @ScienceMagazine study investigated why
https://t.co/e650W6MVcs
—nonpharmacologic intervention (masking, physical distancing)
—reduced international travel
—change in virus lineage dwell times

[Dysautonomia Intl. @Dysautonomia]

Many individuals with #POTS are often misdiagnosed as having anxiety or panic disorder. Read the study finding that POTS patients are no more likely to have anxiety than the general population: https://t.co/6lh1aUPnI2

[Michael Peluso, MD @MichaelPelusoMD]

Lots of attention on cortisol in #LongCovid lately. Here are results from a pilot project in the @UCSF #LIINC cohort. Similar levels between LC and recovered, but morning dynamics appear to differ, esp. in those with post-COVID ME/CFS. Detailed follow up project ongoing.

[PolyBio @polybioRF]

We are excited to announce an $800,000 donation to Mount Sinai to support a clinical trial of the drug rapamycin in patients with long COVID. The trial will be conducted at CoRE: a clinic directed by Dr. David Putrino and PolyBio's Dr. Amy Proal:
https://t.co/oAcPFtyne8

[Amy Proal, PhD @microbeminded2]

I am so motivated to move this new trial forward with @PutrinoLab! Especially because immune parameters in participants will be measured by our amazing collaborator @VirusesImmunity. That analysis will help clarify rapamycin’s mechanism of actions when taken in a low dose

[Eric Topol @EricTopol]

How our brain and body talk to each other, with control of inflammation and our immune response
https://t.co/PfvgcXgOWA @CellCellPress
@rolls_asya @NadineGogolla @PopescuMiranda @SLiberles and colleagues, open-access