Will Freyman @[email protected]

computational biologist. phylogenetics, population genetics. No longer active on twitter, find me at

[Veera Rajagopal  @doctorveera]

Check out this website https://t.co/Twl0T79oz7 that summarizes the phenotypic and genetic characteristics of around 300+ genetic clusters identified in the UCLA biobank. @ChristaCaggiano gave an interesting talk on this fascinating work #ASHG22 #DRIFT22

[Divyaratan Popli @PopliRatan]

Relatedness inference with low-coverage ancient DNA data is still a hard problem. Today, we posted a preprint presenting a new method called KIN that identifies close relatives up to 3rd-degree while differentiating parent-child from siblings: https://t.co/0K7nowvH0p (1/3)

[C. Brandon Ogbunu @big_data_kane]

1/8
25 years ago, today (Oct 24, 1997), 'Gattaca' was released.

Me & @DocEdge85 chose to commemorate the event w/ a technical perspective recently published in GENETICS @GeneticsGSA

Here I'll just post several items related to the broader project.

https://t.co/CbvKIIu5PN

[Systems & Population Genetics Group | O. Delaneau @DelaneauGroup]

New version of SHAPEIT is released (v5). It phases rare variants in the UK Biobank whole-genome and whole-exome sequencing data with great accuracy. Thanks to all co-authors @Rbn_Hfmstr @Diogo_M_Ribeiro @simrubk @ODelaneau !
@DelaneauGroup @dbc_unil

https://t.co/D1sdzsYave

[Shai Carmi @ShaiCarmi]

Improving polygenic risk prediction in admixed populations by explicitly modeling ancestral-specific effects via GAUDI https://t.co/YJmtxEF1pq

[European Virus Bioinformatics Center @EVirusBioinfC]

Summary of the #Bayesian #phylogenetic framework and conceptualization of a variety of methods to improve posterior approximations via Markov chain Monte Carlo sampling. #inference [Review co-authored by EVBC members @suchard_group @LemeyLab] https://t.co/zjw94FLEZR

[Ewan Birney @ewanbirney]

The race/genetics discordance is like nails on the blackboard for me. A reminder - race/ethnicity is selected from societal pre-defined boxes, 1 dimension, ~30 choices. Genetics is measuring someone's DNA over ~300,000 (ish) dimensions of their DNA. They are *not* the same.

[Introgression Papers @_introgression]

MAST: Phylogenetic Inference with Mixtures Across Sites and Trees https://t.co/idoZZR9NiY

[bioRxiv @biorxivpreprint]

Fast computation of principal components of genomic similarity matrices https://t.co/kjMHsRw7NN #bioRxiv

[Matthew Hahn @3rdreviewer]

I really love this paper by @nhcooper123 et al. Small amounts of measurement error can lead to 100% rejection of the simpler (correct) model.

https://t.co/2fpiyoiwVp

[Yi Ding @yi_ding_]

New preprint! We demonstrate that PGS accuracy varies continuously cross individuals within and across genetic ancestry clusters and highlight that PGS should be interpreted through the lens of continuous genetic ancestries. 🧵
https://t.co/cOswARhQ6O

[Diego Ortega-Del Vecchyo @dortega_delv]

The virtual symposium "Using Ancestral Recombination Graphs (ARGs) to Infer Evolutionary Processes" will take place on Friday September 30. You can find the program here: https://t.co/urWq8uhpqk"

[Rui Borges @RBorges23]

Now published in Methods in Ecology and Evolution! https://t.co/ZZ1TdzYscE

[Shai Carmi @ShaiCarmi]

Deciphering the genetic structure of the Quebec founder population using genealogies https://t.co/1fyykldpzF

[Charles Margossian @charlesm993]

Excited to share a revision of the preprint “Nested Rhat: Assessing the convergence of Markov chain Monte Carlo when running many short chains”, with Matt Hoffman, Pavel Sountsov, Lionel Riou-Durand, @avehtari, and Andrew Gelman.

https://t.co/Umos4lxNUk

[bioRxiv @biorxivpreprint]

Demographic History Inference and the Polyploid Continuum https://t.co/qQtvyr0W6L #bioRxiv

[bioRxiv Evobio @biorxiv_evobio]

This population doesn't exist: learning the distribution of evolutionary histories with generative adversarial networks https://t.co/HvuyaTKQTP #biorxiv_evobio

[Andrew Vaughn @andrewhvaughn]

We are officially announcing the Fall 2022 Bay Area Population Genomics (BAPG) conference to be held at UC Berkeley on October 15! Check out our website: https://t.co/gyRhl3il81 where you'll find logistics info + link to registration. Contact me or @YunDeng5 with any questions.

[Jerome Kelleher @jeromekelleher]

#PLOSCompBio: Recombination-aware phylogeographic inference using the structured coalescent with ancestral re ... https://t.co/lJCORTpFSn