Writawrik Bhattacharya

Developmental Neuroscience 🧠 | Research Scholar @TIFRScience, Mumbai | Occasional photographer 📷 | Views are own

[Cell @CellCellPress]

In the latest issue! RegVelo: Gene-regulatory-informed dynamics of single cells https://t.co/UwgMnq1y5T

[Henry De Belly @Henry_de_belly]

Very excited to be sharing our new paper, just out in Nature Cell Biology! https://t.co/uCk077bPo2

The big question we investigate: How do migrating cells put their front 🔴 and back 🔵 in the right place?

[Martin Pera @martinperaJAX]

Unbiased profiling of multipotency landscapes reveals spatial modulators of clonal fate biases https://t.co/OE70AZ1SvX

[antisense. @razoralign]

Echo characterizes the desynchronization of gene expression and chromatin accessibility during cell-state transitions https://t.co/gJvNO7t7Vn

[Jeffrey Millman @JeffreyRMillman]

🚨Excited to share our single-cell multi-omic atlas of #stemcell islet differentiation that predicts cell fate decisions and identifies causal regulators of lineage specification. You can start browsing the data now 👉 https://t.co/zIQXlqjlbc Preprint 👉 https://t.co/7gLx7kr6bu

[nature @Nature]

Nature research paper: Developmental gene expression patterns driving species-specific cortical features

https://t.co/aAYrEW3ayd

[antisense. @razoralign]

TransXplorer: An automated translational discovery platform for RNA-seq data https://t.co/syz94jg6Nd

[Yale Department of Genetics @YaleGenetics]

What drives cell fate decisions during human cortical neurogenesis?

🧠 A new single-cell CRISPRi screen of 44 transcription factors identifies novel regulators including ZNF219, NR2E1, and ARX, with convergent roles in neurodevelopmental disorders 👇
https://t.co/7l6v5lubYF

[Gaurav Chattree @GChattree]

Excited that our TRU-FACT preprint is now live!

TRU-FACT links what individual neurons do in vivo, with who they are molecularly, and who they connect to.

As a neurologist, I’m excited by its potential for understanding and treating circuit disorders.

https://t.co/zFSvbwzq2y

[Vijay Krishnamurthy @Vijay_K_Murthy]

The TIFR PhD program "Physics of Life" aims to train the next generation of biological physics researchers in India. Applications now sought via the JEST, GATE, and CSIR-NET (JRF-eligible) streams. Deadline is May 7, 2026. Details & application form: <https://t.co/rABBnfwGNx>

[Hao Yin @HaoYin20]

3D #SpatialTranscriptomics
Whole cardiomyocyte in adult🐭🫀

10x 10 µm cryosections
3.5 µm BMKMANU S3000 ST chips
WGA stain-Cellpose➡️cell boundary
Dynamic time warping +Optimal transport +Centroid distance ➡️3D registration
2.7k genes/cell

vs 10x VisiumHD, snRNAseq

Intracellular RNA asymmetry
Mito-metabolism at proximal end
Neuronal-like signaling at distal end

https://t.co/7ACZ2ezDa5

[Science Magazine @ScienceMagazine]

Two new studies in Science report findings from cutting-edge molecular approaches that identify the earliest genomic changes occurring in the brains of individuals with Down syndrome.

The studies establish a clear foundation of how trisomy 21 affects the brain’s cells from before birth to 3 years of age.

Learn more in a new #SciencePerspective: https://t.co/qFa6851GgO

[Zoltan Molnar @ZoltanMolnar64]

Hexalaminar structure is a fundamental feature of the cerebral cortex. In primates Layer 5 has historically been subdivided into two laminae, but now we found three clearly defined sub-laminae in historic archive material (https://t.co/1PGR2zOIFF; https://t.co/zhhHyqBWk9).

[Development @Dev_journal]

WNT activity disrupts early neuronal fate specification

This Research Highlight showcases work by Amrita Singh @AmritaCantSing, Shubha Tole @shubhatole and colleagues from @TIFRScience.

https://t.co/GJNHD7Uc3A

[Society for Developmental Biology @SocDevBio]

Before there’s a heartbeat, there’s this little glowing heart in the neural tube 💕 Chicken neural crest cells in magenta. 📸Image by Rocío Márquez, Strobl-Mazzulla Lab @PstroblM #FluorescentFriday #SciValentine

[Volodymyr Nechyporuk-Zloy @vnzloy]

High-plex spatial RNA imaging in one round with conventional microscopes using color-intensity barcodes
Tianyi Chang et al.
https://t.co/fG1Dqc1fho

[allen institute @AllenInstitute]

Electron microscopy is @nature's Method of the Year! 🧠🔬🏆

@naturemethods shares why MICrONS and FlyWire are proof that #ElectronMicroscopy is helping us gain a deeper understanding of the brain and its incredible complexity: https://t.co/ulrxfdJKxJ

#studyBRAIN

[outside five sigma @jwt0625]

some old websites are so good & so outside of distribution

[Society for Developmental Biology @SocDevBio]

🎄 Day 4 of the 24 Days of Development ✨🧬
In 1984, Drosophila homeotic genes were found to be conserved across animals, including humans 🧬🐸. This article highlights a shared genetic toolkit for embryonic development 🔬🌟🎁  https://t.co/Fjav2v2IxL

[Pilaz Lab @ljpilaz]

Neuronal migration in the developing mouse cortex. This movie was generated in organotypic brain slices at embryonic day 15. Overnight live imaging every 10 minutes, using @NikonUSA laser-scanning confocal microscopy. Credit: @C_Kittock