“adhd meds Wow this is what normal ppl feel like” No. “normal” “people” dont “feel like” anything bc they dont exist. you are being stimulated by a stimulant. it feels normal because you live in 5th Reich Methworld
This is the coolest video to witness-
Azul Embraer E195-E2 flew at low altitude over the beaches of Rio de Janeiro, in homage to the Brazilian National Football Team.
This is great news. But I also hope that more countries approve the usage of GS-441524 for FIP, which for some bizarre reason is not the case for most countries including Brazil. This literally saved my cat and could save many others
사실 고양이는 태어날 때부터 신장 청소 능력에 결함이 있다.
AIM이라는 단백질은 혈액 속을 돌아다니며 신장에 쌓인 세포 찌꺼기를 표시해두면,
면역세포가 와서 치워가는 구조다.
사람·개·쥐는 신장이 손상되면 AIM이 자동으로 출동해서 청소를 시작하지만,
고양이는 청소부가 출동을 못한다.
고양이의 AIM은 평소에 IgM이라는 단백질에 꽉 묶여 있다.
문제는 이 결합력이 다른 동물보다 1,000배 강하다는 것.
신장이 아무리 망가져도 AIM이 풀려나지 못한다.
이렇게 되면,
찌꺼기가 신장에 계속 쌓임 → 만성 염증 발생 → 신장 조직이 딱딱하게 굳음 (섬유화) → 기능하는 신장세포 감소
→ 만성 신부전 진행
이게 바로 15살 이상 고양이의 80%가 신장병에 걸리는 이유이다.
일본 도쿄대 미야자키 교수팀이 개발한
rAIM 주사제는
묶여있는 AIM 대신, 자유롭게 움직일 수 있는 재조합 AIM을 주사로 보충해주는 방식으로,
임상시험 결과는 다음과 같다.
치료 안 한 그룹: 1년 생존율 20%
rAIM 주사 그룹: 1년 생존율 80~83%
현재 2026년 일본 승인 신청 완료 되었고,
빠르면 2027년 봄 상용화 예정이다.
지금까지 고양이 신장병은 "진행을 늦추는 것"이 전부였는데, AIM은 진행 자체를 멈추는 최초의 치료제가 될 수 있다.
Humans are really bad at grokking log scales, i.e., “there’s levels to this shit”
Among my friends I’m the insanely fit cyclist guy; on my weekly group ride I’m one of the slowest. The fastest guy there couldn’t sniff a pro contract
This applies to literally everything
This post reminds me of Rebecca Solnit’s whole argument in Wanderlust, that walking is tied to freedom, imagination, and forms of experience modern life keeps trying to engineer out of us. That is why solo life abroad can feel so electrically alive. You are not buffered by habit, language mastery, or social certainty. Even ordering lunch becomes a tiny existential act
I feel a lot of people are using AI tools the way you'd use a car if you didn't know that you can take your foot off the gas.
People reporting "well its immensely useful, but gee its stressful to go 110mph to the store, around all those pedestrians"
some human things I’m tracking
> religious schools, retreats, pilgrimages, and faith-based media rising as people search for moral certainty
> “human-only” spaces: restaurants, schools, clubs, apps, and retreats that ban synthetic media, recording, phones etc
> pet daycares, dog hotels, pet insurance, and premium pet food begging to skyrocket as loneliness increases and people defer to furry friends
> post-career identity markets: people living longer and needing new titles, tribes, rituals, status games, and reasons to wake up after professional relevance fades
> private members’ clubs solidify as paid social graphs for adults who lost community to remote work
> dating apps fragmenting into belief-based and lifestyle-based matchmaking since infinite choice has become exhausting
> family formation will become a premium service category: matchmaking, fertility, childcare, coaching, home design etc
> eldercare will start shifting to more at-home treatments due to ai (over time it’ll be cheaper than care homes too)
> analog cameras, vinyl, printed books, notebooks, “dumbphones,”and mechanical watches grow as anti-synthetic status objects
> handmade goods becoming trust objects because machine abundance makes human effort valuable again
> live events becoming more valuable as recorded media becomes forgettable
> glp-1s are just the first mass consumer drug for editing desire, more to come.
> fertility tech booming because career timelines and biological timelines are now in open conflict
> oral exams, apprenticeships, portfolios, and live demonstrations returning because written work is becoming cheap to fake
> digital detox products growing
> air quality, water filtration, food sourcing, and sleep environments becoming mainstream status markers
> luxury shifting from owning more things to accessing peace, beauty, privacy, time, and high-trust rooms
> the biggest consumer opportunities coming from psychological scarcity: belonging, certainty, attention, embodiment, trust, and continuity
@WeiseFranklin@Prefeitura_Rio Os números estão inflacionados e não tem mais como usar valores reais, minha proposta:
Plano Pessoa Real pra multidões:
- 1 URP (Unidade Real de Pessoa) = 1 pessoa
- Valor da URP atual = 10
- 2M / 10 URP = 200 mil pessoas
you need to be modifying your speech to piss off the nonbelievers:
- DON’T say “unrelated”, DO say “orthogonal”
- “random” -> “stochastic”
- “this is fine ig” -> “local minima”
- “sorta like” -> “isomorphic”