2025 US guidelines for the management of ACS (STEMI and NSTE-ACS) just released. Insertion of a
microaxial flow pump (Impella) to prevent death in in cardiogenic shock has received a class IIa LOE B-R recommendation. IABP and VA-ECMO are class III for rourine use.
2024's top 10 advances in biology (🧵)
1. Progress in longevity
Blocking the pro-inflammatory cytokine, IL11, extended healthspan and lifespan (in mice!)
Old mice without IL11 look healthier, they're stronger, and they live longer
https://t.co/Y0Raog12xk
#AFib can impair ventricular function over time in up to 50% of patients.
AF-induced #cardiomyopathy mechanisms include systemic inflammation, oxidative and metabolic stress, cardiomyocyte calcium mishandling, & structural remodeling. https://t.co/VIt9RmewuH
#JACCHF@XWehrens
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