As part of my PhD project, we investigated the 3D genome organization of murine T cells, focusing on roles of SATB1 and CTCF. Our work was published @NatureComms https://t.co/VdrJs56ui6 and our optimized HiChIP and Hi-C protocol in https://t.co/rEKTzXlEi3 @MPs_MDPI 🧵👇
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So proud of @zelenkt for taking home the Postdoctoral Presentation Competition at the @MoffittResearch 2026 Distinguished Lecturer Symposium! 🎉👏 #proudPI
And what a privilege to have Dr. Jennifer Wargo as this year’s Distinguished Lecturer, truly inspiring!
🚨 Our conference on academic culture is just around the corner! 🚨
What do top researchers need from their institutions? How can we create an environment where scientists thrive and achieve their best? 👨🔬💪
Join us to discuss opportunities and challenges in fostering a supportive research environment that leads to excellence!
🎓Encourage your students to attend too! They will gain insights into the broader aspects of academic culture, and we believe that good practices should be nurtured from the early stages 🙏
📅 June 12, 2024
📍@CIIRCCTU in Prague & online
🎟️Registration & tickets: https://t.co/n8vYtnRaSR
🙏 @AvHStiftung@ERC_Research
Our work using single-molecule chromatin configurations to link TF binding to gene expression is now out on bioRxiv! Amazing effort from @bgrdoughty, @MichaelaThinks, and @juliaschaepe, and an immensely rewarding collaboration with the @BintuLab: https://t.co/u9aNQV4Ub9 [1/n]
Great paper. I strongly agree that causal gene regulatory network inference (i.e. where u can actually claim gene A causally and directly regulates gene B) using mRNA alone is impossible IMHO. Even from perturbation expts. I think this is impossible. 1/
Researchers @zelenkt@BabiSpilianakis part of @IMBB_FORTH @MSCActions @Mariecurie_alum show SATB1, a predominantly T-cell specific protein, helps to establish a regulatory, finer-scale 3D organizational layer on top of pre-existing chromatin scaffolds.
https://t.co/ilOaHbkq5q
This work was led by Eric Helm and @dorina_avram@MoffittNews . However, it would not be possible without help of our numerous collaborators including Bryceson's lab, Conejo-Garcia's lab, @gatechatl@Zhang_Lab_UFL @akwiatkowski @keselowsky @BSheridanLab and many others.
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In our latest contribution @SciImmunology we characterized important regulatory roles of protein Bcl11b in tissue resident memory CD8 T cells https://t.co/LRjrnNtlGy
The key points summarized below 👇
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