Zibo Chen

Assistant professor @westlake_uni. Synthetic biology. Pilot (PPL, IR).

[Zibo Chen @ZiboChen]

New toy in the lab 😃

[Gabriel Rocklin @grocklin]

Longer thread later, but if you are designing small proteins or want to building a stability predictor using 1.8 million highly diverse experimental measurements… credit to @ChoYehlin and @KotaroTsuboyama !

https://t.co/4U5ULToaat

[Yodai Takei @yodai_takei]

I'm very excited to share that I've started a new position as a Group Leader at CZ Biohub NY! @biohub

[Katie Galloway @GallowayLabMIT]

Could the folding of synthetic gene circuits in 3D shape how genes are expressed? Today @ScienceMagazine we report on the role of gene syntax in shaping feedback between transcriptional activity and genome folding for advanced circuit design🧵 (1/n)

[Zibo Chen @ZiboChen]

@GallowayLabMIT Congrats Katie, well deserved!

[Katie Galloway @GallowayLabMIT]

Join us next March'26 at
Synthetic biology for Health and Sustainability

Abstracts deadline: December 1st, 2025

Link below 👇
Great lineup of speakers and excellent venue: Kristala Prather (MIT), Luis Serrrano (CRG), Priscilla Briquez (Freiburg), Zibo Chen (Westlake U) @ZiboChen , Tobias Erb (Max Planck), Cleo Kontoravdi (Imperial College), Debora Marks (Harvard), Nicola Patron (U of Cambridge), Sai Reddy (ETH), Anna Rising (Karolinksa), Edda Schulz (Max Planck), Claudia Vickers (Queensland U), Chris Voigt (MIT) @Geneticdesigner, Harris Wang (Columbia)

[Zibo Chen @ZiboChen]

@MoKhalilLab @BashorLab Huge shoutout to @DamonRunyon for funding this work. And check out this stunning cover art by the unstoppable first author, Xiaoyu, with a Haiku interpretation from Gemini:

Small bots read the stone

Linked by glowing, sensing wire

Many arms see one

[Zibo Chen @ZiboChen]

Thrilled to share our new paper on MASS (Multivalent Antigen Sensing Simulator)!

We built a fast and accurate simulator to calculate multivalent binding KINETICS from monomeric properties, enabling sensing of cell surface antigen types and densities.

https://t.co/W42OrxTWIc

[Zibo Chen @ZiboChen]

@MoKhalilLab @BashorLab We also optimized the code to be fast, so you're not waiting hours to simulate higher valency binding kinetics. Code is available here: https://t.co/apXOZwMU3c

[Zibo Chen @ZiboChen]

@adam_broerman @Nature Congrats Adam, beautiful work.

[Zibo Chen @ZiboChen]

Always fun and enlightening to see a talk by @UriAlonWeizmann

[Itai Yanai @ItaiYanai]

Legend David Baltimore died yesterday. He understood the way things should work: "the real contribution of @MIT is that it doesn't take itself too seriously. It takes ideas seriously, but the people are relatively informal. They are not self-aggrandizing the way academics can be.

[Zibo Chen @ZiboChen]

@ShiyuXia @UCBerkeley @UCB_Chemistry Congrats Shiyu!

[Zibo Chen @ZiboChen]

@SynBioGaoLab Congrats Xiaojing!

[Xiaojing Gao @SynBioGaoLab]

LIDAR is out! https://t.co/hmzijbK03t We've improved a lot, e.g., making MESA-like LIDAR work, RNAseq of on-/off-target editing, and optimizing RNA delivery. We are one baby step closer to making it useful for therapeutics. NIH high-risk high-reward program provides key support.

[Bashor Lab @BashorLab]

🚨NEW PUBLICATION ALERT🚨: In a paper out today in @ScienceMagazine we describe a way to build synthetic phosphorylation circuits with customizable sense-and-response functions in human cells. Check it out at https://t.co/hrA7Mys9PZ. 🧵1/n

[Zibo Chen @ZiboChen]

@yodai_takei Thank you Yodai! Hope all is well.

[Zibo Chen @ZiboChen]

Excited to finally share Perceptein, a PERCEPtron made of proTEINs: https://t.co/saaO8ogAc3

[Zibo Chen @ZiboChen]

@RongrongDu123 Thanks Rongrong, the pressure is on you now 🙃

[Zibo Chen @ZiboChen]

@Ella_Maru Thank you for the kind words, Ella!