Nomad

DESCI IN LABS

[Nomad @AI_entist]

Lately, I’ve realized that more time I spend in DeSci, the more it feels like home. Other crypto projects just don’t hit the same—DeSci pulls you in with its potential, and the deeper you go, the harder it is to look away.

#DeSci #Preprints

[Nomad @AI_entist]

Been working on something .. 🤫⏳

#BNB

[Nomad @AI_entist]

@that_investor Congratulations to both of you!

[dWallet Labs @dWalletLabs]

🧵1/12
We're excited to share REFHE: Fully Homomorphic ALU, our new paper introducing an FHE scheme that natively supports both arithmetic and logical operations on 64-bit machine words.

This is a step toward treating FHE not as a circuit model - but as a real compute model.

[d3h3d 「🦑」 @d3h3d_]

here’s what you actually need to know:

- fhe is cutting edge cryptography that will redefine privacy and security
- fhe in web3 has a huge blocker in the form of no viable threshold fhe schemes
- existing solutions are permissioned, centralized, slow and non-scalable - and they are delivered by companies like @zama who raised over $80m and focus solely on fhe
- we delivered, as usual, a 1,000x improvement on the existing state of the art - permissionless, decentralized, fast and scalable
- we did that, as usual, in way less time, with way less funding, and without it even being our main focus

bottom line: we are the undisputed leader when it comes to threshold cryptography, which is one of the most important foundations for web3 technology

[Nomad @AI_entist]

Incredible to see the dedication and patience it takes to build a project from ground—heartbreaking to see it dismissed as a scam over price action. @bioprotocol impact on science on-chain is far bigger than token’s value. it’s a transformative shift in how we approach #Tech

[Paul Kohlhaas bio/acc @paulkhls]

Anyone who says DeSci is a scam is jaded by short termism and has lost the values that created Bitcoin and Ethereum. Solving long term problems for real people.

@bioprotocol first BioDAO on Solana is by Harvard alumni and biotech legend @eperlste who has dedicated his life to helping families find cures for rare diseases. Auction is reaching 10,000 SOL and closes in the next hour.

I want to thank the @solana community for the warm welcome during an incredibly tough downturn. Its proof people want utility and believe in DeSci.

Build long term @cz_binance cautioned recently. And here's the story:

I first emailed @eperlste in 2019. Ethan was an inspiration to me early on when I looked for answers to a crisis I had seen since my teenage years. At 14 I asked myself why family members were prescribed anti depressants or adderall - I felt this was a failing system. I fell into a rabbit hole of online biohacking forums and geeked into all sorts of things from longevity to nootropics and genetics.

I first cold emailed him in 2019 when I founded @Molecule_dao after going to the only community I could discover about what I wanted to build. His talk was so inspiring I wanted to learn from him. I emailed him twice and second time told me he didn't have time to give advice.

The Open Source Pharma foundation launched by a policy prof at Harvard with an Indian institute simply because they decided they wanted to develop drugs without patents and work in github repos. They accelerated numerous drug candidates in tropical diseases and malaria. Gates foundation funded a stage 1 trial with very promising results. But nobody wanted to ever fund a stage 2 trial because there was no potential commercial strategy. We tried to launch a DAO with them, but

The basic premise makes so much sense - if we did drug research in the open, scientists collaborate and we accelerate cures. But when I heard that a promising malaria vaccine funded by the gates foundation had no hopes of ever making it to trials because nobody funds drugs without patents I realised how broken the system was.

Anyone who tells you biotech research should be open doesn't understand what the system incentivises for. It incentivises for returns, not impact or outputs. Not cures. It punishes open innovation because this threatens the margins.

But Ethan tried it with @PerlaraPBC which you can find many stories about. He pitched biotech VCs a new model of a public benefit corporation incentivising data sharing among families. Unfortunately, post seed stage biotechs need to play by the rules and I recall he failed to raise follow on funding. But he learned that patients are champions, they make it happen.

In 2021 Ethan emailed me out of the blue and proposed I connect with another rare diesease founder excited by VitaDAO. @VibeBio was focusing on this use case and we had enough to do with our first dao so things went dormant again.

Brilliantly @EMcCarthyPage invited Ethan to speak at DeSci Berlin last year and he gave the best talk in my view and laid out the vision for the DAO. Its simple:

1. Rare diseases are not lucrative for industry bc populations are so small, but its the life and death of a child and could be prevented. No insurance will cover you, so you're basically an entrepreneur in this disease now. @blader recently became on $MIRA turned into a beautiful story.

2. Rare diseases can be cured but scientists need data and impulses from patients and a bit of funding. What normally happens in board rooms and strategy meetings and expensive labs is now run by a father trying to save his daughter at every cost, and prevent anyone else from facing this.

3. Ethan realised you can cut the costs down massively by helping the parents project manage, managing the data safely which is sensitive, and budgeting costs and refining drug development. Sharing data is sensitive and why trust crypto, patients have made bad experiences with data sharing powered by $CURES

Ethan got a therapeutic into stage 3 FDA for under 5 million. That normally costs billions and takes years.

Regulator actually works with you here and fastracks because the need is so big.

@bioprotocol gave Ethan and team builder grant in Q3 last year so he could accelerate his work. We knew we wanted to launch. Instead of building a dao, he went out took the 100k and said let me show you what this gets you. He ran a yeast screen and discovered 2 novel targets and filed two patents.

When you ask, does $CURES have a product its selling? Bitcoin doesn't sell a product. It provides an alternative to a massive real world problem. @endrarediseases provides a system that could generate 1000s of products for millions and would've never been previously possible. And the consumer will hold $CURES for life because they care about access not profit.

Incredibly grateful to @akshaybd @solana @rajgokal @nkumar23 for encouraging us to bring DeSci to Solana! Onwards

[BRICS News @BRICSinfo]

JUST IN: Oxford scientists claim to have achieved teleportation using a quantum supercomputer.

[Nomad @AI_entist]

@crisprAI @bioprotocol @Nuclease_DAO 👀👀

[Blockworks Data @MessariCrypto]

DeSci’s market cap, excluding long-tail memecoins, is $1.2 billion, which is just 0.035% of crypto.

While Ethereum still hosts 49% of projects launched during previous cycles, Solana is gaining ground, accounting for 40% of projects launched post-2023.

The Rise of PHDegens.

[Nomad @AI_entist]

2024 marked the tipping of scale⚖️,2025 is where the true breakthroughs unfold. Get ready to witness the results of tireless efforts.

This is just the beginning, fasten your seatbelts #DeSci is about to soar at Mach 3 and redefine the traditional Science!

$PRNT $BIO

[Nomad @AI_entist]

@crisprAI 👀👀

[Nomad @AI_entist]

The pace at which we at @preprints_io are building is just mind blowing.

Just weeks after launching @SPHNX_ai , we now have https://t.co/Hq0aLFW4cJ ,The Work never stops here! Many more to come..

Go try and give your review below!!

Note: Only token for @preprints_io is $PRNT

[Aaron @AaronSolanaa]

The new @caffeineai by @dfinity may not be just a game changer for $ICP

But for the entire AI x Blockchain space

@dominic_w explains here

[Imprnt @imprnt_ai]

Pleased to see our work on "a Blockchain Protocol for Human-in-the-Loop AI" cited in @_Qubic_'s recent publication. Looking forward to the promising direction they are exploring towards decentralized AGI.

Read our preprint here: https://t.co/3KkXOINCfF

[Binance @binance]

Introducing @bioprotocol $BIO on Binance Launchpool!

Farm BIO by locking BNB and FDUSD 👉 https://t.co/mHAc3Vd5pH

[Nomad @AI_entist]

@ErectusDAO Lukas Weidener

[Imprnt @imprnt_ai]

🔍The most promising CS preprint published last week, according to our scoring model at https://t.co/TCNezCJPH3, is "Leveraging Black-box Models to Assess Feature Importance in Unconditional Distribution" by Chunlin Li and Jing Zhou.

The paper proposes a novel approximation method for analyzing how features affect outcome distributions in black-box models, demonstrating sparse and faithful results across various experiments.

Read it here: https://t.co/51QeuZoimJ

[Globe Eye News @GlobeEyeNews]

BREAKING:

Russia announces it has developed a cancer vaccine, free for all citizens.

[Nomad @AI_entist]

@bionicdao_ @Hippocrat_io 🙌🙌

[Nomad @AI_entist]

RT @preprints_io: LLMs' understanding of language means security breaches can occur through semantic manipulation - making traditional info…