Ali Nikish

Scientist, artist, avid birder
MIT... CRISPR Tx... UPenn (Cremins Lab)

[Jenn Cremins @CreminsLab]

Next up is MASTR-seq - a protocol for Cas9-based capture of target loci for multi-modal inquiry of short tandem repeat tracts and DNA methylation at single-allele resolution using Nanopore long read sequencing. Led by @chuanbin_su

[Jenn Cremins @CreminsLab]

We're excited to drop two new manuscripts on technologies for multi-modal single-allele or single-cell inquiry. First up: FISHnet - a computational method for finding domain-like chromatin structures in sequential Oligopaints imaging data. Led by @PatelRohanD and @KennethHPham

[Zoltan Simandi @simandi_zoltan]

Great teamwork from many other rising stars from the @creminslab! @AliNikish @abrahamjwaldman @hanseul_ryu and Heesun Choi! Special thanks to @PaquetLab for their support with the cell lines and model system. #TeamWorkMakesTheDreamWork

[Harshini Chandrashekar @HarshiniChandr8]

I am excited to share our new work from @CreminsLab on genome’s structure-function relationship in post-mitotic human neurons and a neurological disease context (https://t.co/cAgyuqCCyg)! (1/n)

[Ali Nikish @AliNikish]

The project I collaborated on as an undergrad was published this week in AJHG! This project was part of my first experience in a lab and contributed greatly to my interest in genetics, epigenetics, and neuroscience :)

[Neville Sanjana @nevillesanjana]

TWEETORIAL on our new paper characterizing loss of the autism-associated gene CHD8 using isogenic CRISPR-edited stem cells and neurons! ✂️🧬🧠

Link to paper: https://t.co/7V0vaMyhtD

[Jenn Cremins @CreminsLab]

We are tremendously excited to share a new 5-year project led by Linda Zhou https://t.co/7rtK7S2PUr. By way of the 3D genome and inter-chromosomal interactions we discover short tandem repeat instability and heterochromatin silencing on autosomes in fragile X syndrome. 1/n

[Ali Nikish @AliNikish]

Congrats!!!

[Ali Nikish @AliNikish]

Thank you! Very excited to share this news about the next steps in my PhD training

[Ali Nikish @AliNikish]

With NIH Pioneer Award, Jennifer E. Phillips-Cremins Will Study Genome Folding’s Role in Long-term Memory https://t.co/4cWf4OxIZi

[Ali Nikish @AliNikish]

"Supported research this year includes understanding how long-term memory might be encoded in the shape of folded DNA in our neurons" 👀 Hooray!!!

[NIH @NIH]

News: NIH supports 106 grants featuring high-risk, high-reward research https://t.co/LUhnryhx0R

[Ali Nikish @AliNikish]

Congratulations! Looking forward to you joining us in the Cremins Lab

[Ali Nikish @AliNikish]

The Cremins Lab published an opinion piece today in Molecular Cell discussing in situ genome sequencing
@CreminsLab

https://t.co/hRUNUH77hz

[Ali Nikish @AliNikish]

I came back to twitter today after ~5 years to tweet about a science paper and boy did I pick the right day to return LOL [laughs in democracy is crumbling]

[NPR @NPR]

BREAKING: Twitter has permanently banned President Trump from the platform, citing "risk of further incitement of violence."
https://t.co/NBzQZQNz2f

[Ali Nikish @AliNikish]

Updated link: https://t.co/OQTQckqKQb

[Daniel Emerson @emersond1105]

Very excited to release our work today on Biorxiv. https://t.co/e59ajw2NNe To date, a clear genetic sequence directing the locations in the genome where origins of replication fire has not been definitively found in humans. 1/n

[Daniel Emerson @emersond1105]

Very excited to release our work today on Biorxiv. https://t.co/e59ajw2NNe To date, a clear genetic sequence directing the locations in the genome where origins of replication fire has not been definitively found in humans. 1/n

[Ali Nikish @AliNikish]

@realDonaldTrump gives a speech on religious freedom, proceeds to bash Muslims. Please go back to hiding under your bridge

[Nature Medicine @NatureMedicine]

Combining PI3K & mTOR results in regression of breast #cancer brain metastates in mice: https://t.co/3vvspo76UB

[Ali Nikish @AliNikish]

So lucky to meet @Astro_Cady tonight at @MIT ! She shared great stories about "everyday" life in space @NASA

[Koch Institute at MIT @kochinstitute]

Using #CRISPR, KI researchers have developed a new approach to rapidly analyze genes mutated in tumors http://t.co/ruHSzFzApH

[MIT Technology Review @techreview]

The Price of Pollution:
http://t.co/gKbyPowWsV