chuanbin

Staff Scientist @Creminslab @washumedicine @WashUGenetics @WashUMedNeu | Exploring genome instability in neurological disease, Alumni @FudanUniv @Yale @Penn

[Bret Freudenthal @Freudlab]

📣 The 2026 Midwest DNA Repair Symposium is coming to Kansas City (registration is open)

🗓 May 30–31, 2026

✨ Talks will be selected from abstracts, with a strong focus on trainees and new investigators.

Please RT & share with your labs!
🔗 https://t.co/qq53P4UW6V

[Kenneth Hoàng Phạm 🏳️‍🌈 @KennethHPham]

I am excited to share our new work from @CreminsLab heterochromatin in fragile X syndrome (FXS), the most common monogenic cause of autism spectrum disorder. We previously described ectopic H3K9me3 domains in FXS, BREACHes, though the clinical significance is unexplored. 1/n

[Urvi Shah @UrviShahMD]

The geneticist who uses science to free parents wrongly convicted of killing their children
@NaturePortfolio
https://t.co/8ipwqeFtJo

[K Titus @titusk99]

I'm excited to share our new publication in @CellGenomics! We examine the structure-function relationship between chromatin looping and RNA polymerase II-mediated gene expression during neural lineage commitment.

Check it out!
https://t.co/2Ea8CEu913

[Rohan Patel @PatelRohanD]

Howdy! I'm thrilled to introduce FISHnet, a computational tool designed to identify chromatin domains within sequential Oligopaints DNA FISH data.

Check it out on BioRxiv https://t.co/6Nn3DApYHr

🧵 ⬇️ ⬇️ ⬇️ (1/8).

[Sarah Aitken @S_J_Aitken]

🎉New paper🎉Introducing #StrandInteractions, the sequel to #LesionSegregation, published today @Nature

Strand-resolved mutagenicity of DNA damage and repair https://t.co/VTP3h139Q4

Here’s what we discovered about (a)symmetry in replication, transcription & #mutagenicNER
[1/13]

[Mitch Guttman @mitchguttman]

What are the functional roles of 3D genome organization? Our paper in @Nature led by @_prashantbhat demonstrates how dynamic 3D genome organization around nuclear speckles plays a crucial role in regulating mRNA splicing efficiency. https://t.co/8KwfJHQWTt

[chuanbin @chuanbin_su]

Last but most importantly, this work would not be possible without the generous dedication from all my generous colleagues @KRaanin,@ThomasMalachowski, @Ravi_boya9, @hanseul_ryu, @lindazh0u and surely my mentor @CreminsLab. A deep gratitude to @kristenbrennand & @FulcrumTx (6/6)

[chuanbin @chuanbin_su]

Excited to introduce MASTR-seq, Multiplexed Analysis of Short Tandem Repeats, a multi-modal method for accurate sequencing of short tandem repeat tracts and DNA methylation across multiple samples. Now on biorxiv(https://t.co/08goWSzTl0). (1/6)

[chuanbin @chuanbin_su]

Our approach is broadly applicable beyond STR detection to any somatic or germline genomic mutations, including transposons, indels, telomere and peri-centromeres. It can be easily performed by any researcher with access to nanopore MinION flow cell. (5/6)

[chuanbin @chuanbin_su]

Very inspired to have been involved in this very challenging but ultra exciting project since I joined @CreminsLab. The discovery of BREACHes let us understand the disease in a new way, but it’s just the beginning. The more is yet to come. Pls stay tuned. https://t.co/HN6QOQjMUZ

[chuanbin @chuanbin_su]

@spencerhaws @UWMadison @CreminsLab @PennEpiInst @pennbioeng Big congratulations to Dr. Haws!

[chuanbin @chuanbin_su]

Great article: Functional Enhancers Shape Extrachromosomal Oncogene Amplifications. https://t.co/sa7sI45eM5 #ReadByQxMD

[chuanbin @chuanbin_su]

@BenGolliver Lao James is really caring for funs

[chuanbin @chuanbin_su]

Great article: An operating system for the biology lab. https://t.co/KAhIh1eQRW #ReadByQxMD

[Biola M. Javierre @BiolaMJavierre]

Methyl-HiC, DNA methylation and genome architecture in a single cell. https://t.co/WudNev75iz

[Power 106 @Power106LA]

The internet is literally undefeated 😭😭😭 #Drake #KawhiLeonard
https://t.co/9w3mFWghRr