Andreas Langen

@UCSF CCB PhD candidate @ZaroLab, @USC B.S. biochemistry

[Zaro Lab @ZaroLab]

So proud to see this incredible and super fun story officially out! Congrats @EckerChem and @AndreasLangen5!!!!

[Andrew Ecker @EckerChem]

It’s finally out now in @ACSCentSci and better than ever!

https://t.co/m71o29Gxo0

[Zaro Lab @ZaroLab]

Is arginine the next frontier in covalent chemistry? We think so! Check out our latest work in collaboration with @IanSeiple where we utilize ninhydrin as a selective warhead and probe for reactive arginines!

[Andrew Ecker @EckerChem]

Is 2026 the year of arginine?
Covalent discovery and chemical proteomics have largely focused on cysteine and lysine, leaving other functionally critical residues underexplored.
In our new preprint, our joint Seiple and Zaro Lab team asked: Can arginine be targeted covalently? 🧵

[Davide Ruggero @RuggeroDavide]

Happy to share our new work with @haognguyen on targeting mRNA translation of oncogenes by RNA structure remodeling with a small molecule zotatifin. Congrats to ⁦@DuyguKuzuoglu⁩ an amazing postdoc and all the authors and collaborators!

https://t.co/RGH6wZqkLl

[Prof. Nikolai Slavov @slavov_n]

Biological systems find ingenuous solutions. Almost anything that can happen, happens.

Still, I would not have guessed a role of RNA-binding proteins on the cell surface.

The Flynn lab are boldly investigating glycoRNAs and following their leads.

[Zaro Lab @ZaroLab]

We are hiring! Come join us!

[Andreas Langen @AndreasLangen5]

woohoo!!!!!!!!! 😁 check out this preprint from the lab!

[Zaro Lab @ZaroLab]

You are what you eat! We leveraged chemical proteomics to discover that macrophages redeploy intact surface proteins made by their cancer cell meals during phagocytosis. These proteins are functional, and redeployment may explain the etiology of the TAM. https://t.co/RIZIGzD8bS

[Covalent Modifiers @CovalentMod]

Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA Display https://t.co/QlPVG1YtYt

[Hamachi Lab. @HamachiLabKyoto]

Happy to share our new paper in @nchembio!
Photoproximity labeling of endogenous receptors in the live mouse brain in minutes
https://t.co/WAeWQsPb4Z

[Keriann Backus @Keribackus]

So excited to to share our lab's photosensitizer proximity labeling platform, POCA, which combines Janelia Fluors (thanks @rhodamine110!) with HaloTag and cholesterol-based probes to define the intracellular cholesterol interacting proteome. Congrats to Andrew Becker and team!

[Keriann Backus @Keribackus]

Bit of good news to end the week---and a big big thank you to everyone who helped make this possible, especially all members of our lab past and present, mentors, letter writers, colleagues, friends+family.

[Matt Pratt @MattRPratt]

My lab @USCChemistry has a postdoc position open for an enthusiastic individual interested in protein posttranslational modifications. Background in carbohydrate or peptide/protein chemistry is a plus but not a requirement. https://t.co/sb8haPAEFv

[Milo B. Fasken, Ph.D. (he/him) @MiloFasken]

Wonderful talk by Jonathan Perr! So many cool possibilities for glycoRNAs!
#RNA24
#RNA binding proteins and #glycoRNAs form domains on the cell surface for cell penetrating peptide entry | bioRxiv https://t.co/uyUToMwYO5

[Science Magazine @ScienceMagazine]

Lab-kept bumble bees roll small wooden balls around for no apparent purpose other than fun, revealed a 2022 study.

Learn more on #WorldBeeDay: https://t.co/72GH2Ptkru @NewsfromScience

[Zaro Lab @ZaroLab]

So excited to share this story with the world! A mimic of the mammalian ‘don’t eat me’ signal CD47 encoded by a pathogen!

[Covalent Modifiers @CovalentMod]

Discovery of a Tunable Heterocyclic Electrophile 4-Chloro-pyrazolopyridine That Defines a Unique Subset of Ligandable Cysteines https://t.co/EK1dY8QtKw

[Cell @CellCellPress]

In the latest issue! High fat intake sustains sorbitol intolerance after antibiotic-mediated Clostridia depletion from the gut microbiota https://t.co/y0xe76lWJ9

[Javarcia Ivory @javiral19]

i grew up on pretty boy swag so i know my worth

[Science Magazine @ScienceMagazine]

By watching 10,000 maggots demolish a pizza in 2 hours, scientists have a better sense of how they gobble food so quickly.

🍕 Learn more on #NationalPizzaDay: https://t.co/DYLTt8Gpnr