The End of the Failed LDL / ApoB Bad Cholesterol Hypothesis
I had a heart attack at 52 with normal LDL.
The 70 year LDL cholesterol hypothesis is crumbling before our eyes as heart disease remains the number one killer on earth.
I spent six years reading thousands of published studies. I assembled a team of four physicians. And I found the answer.
It was never the LDL/ApoB particle.
It was never the "Bad Cholesterol"
It was always the wall of the artery
The wall is rising. 🧵
Today marks a historic milestone for metabolic psychiatry!
Baszucki Group is launching the Global Network for the Advancement of Metabolic Psychiatry (MetPsy), alongside a $20 million investment to establish the McLean Center for Metabolic Psychiatry at McLean Hospital, a Harvard Medical School affiliate.
For years, I've argued that mental disorders can be understood as metabolic disorders impacting the brain. Advancing this field requires rigorous scientific research, innovative clinical care, and education and training to bring emerging discoveries into clinical practice.
This investment will help advance all three.
I'm particularly excited to be leading the education and training initiatives at both McLean Hospital and MH². We'll be developing clinical case conferences, journal clubs, symposia, CME programs, and other opportunities for clinicians and scientists to learn, collaborate, and help shape the future of metabolic psychiatry.
I am deeply grateful to Baszucki Group for their extraordinary commitment to this field and to the many researchers, clinicians, patients, and families who have helped bring us to this moment.
Patients deserve better treatments, and together, we have an opportunity to transform mental health care.
Read the full announcement:
https://t.co/YwX2zOo96g
The @nytimes and @apoorva_nyc owe parents the facts behind their alarming hepatitis B reporting.
The paper they discuss is a “modeling study” or simulation based on assumptions, not a study of evidence or outcomes. The model assumes allowing parents and doctors to decide when or whether to vaccinate would drive vaccine completion down to just half of children. The researchers did not observe that decline or establish that our policy would cause it. Yet the Times obscures that assumption while amplifying the alarming prediction it produces.
At its December meeting, ACIP recommended that parents and doctors decide whether and when to begin hepatitis B vaccination. CDC’s January update to the childhood vaccine schedule carried forward that approach. Yet the researchers assigned sharply different vaccination rates to the two, producing different infection projections. The Times should explain what justifies that difference before attributing its alarming 83% figure to the January update.
The article also gets the recommendation wrong. The recommendation did not tell parents to wait until two months to decide. Parents could choose vaccination at birth. The two-month suggestion applied to administering the first dose if parents deferred the birth dose.
The recommendation retained birth-dose vaccination for babies whose mothers have hepatitis B or whose status is unknown. For babies whose mothers test negative, it gave parents and doctors a choice about when or whether to begin vaccination.
I reject the idea that respecting parents’ choices means abandoning children’s health. Under my leadership, HHS puts informed consent, individual medical circumstances, and conversations between parents and doctors at the center of health decisions.
I welcome rigorous scrutiny of our policies. But scrutiny demands accurate reporting, defensible assumptions, and evidence. The Times should correct its error and explain the assumptions behind its headline. Parents deserve the full story.
https://t.co/xyXfXVdDpq
Elon Musk used zero tax dollars to create the first flying car.
Gavin Newsom spent billions of your dollars on a railroad that never got built.
Just saying.
The FDA just submitted an interim policy to expand access to compounded peptides nationwide.
This is HUGE!! 🇺🇸🔥
This isn’t about whether you’re for or against peptides. It’s about whether you’re for or against MEDICAL FREEDOM. Big step towards patient access and choice.
https://t.co/Y3jNAekadM
BEZOS: When you're in the polling booth and you're thinking about who you're going to vote for, think about this. If there's a politician that is picking villains and pointing fingers, that's probably means they don't have a solution
If there's an executive at one of my companies, instead of working on a root cause and a real fix, all they did is point fingers and blame people, we would exit them quickly.