Super cool indeed! Expect more multimodal foundational models for biology soon! 🚀
#biotechnology#Genomics
Sequence modeling and design from molecular to genome scale with Evo https://t.co/ZZw69ktTok
How well do🧬 DNA LMs perform on prediction tasks that are biologically relevant, are naturally very imbalanced and require reasoning over long contexts? We present BEND, a benchmark for DNA LMs on the human genome
https://t.co/VTHS2OeyDT
Interested in LLMs for genomic research but don't know where to start? looking for a review/survey to get started in this field? 👇👇😀
I am very excited to share that our review paper titled "To Transformers and Beyond: Large Language Models for the Genome" is now available as a preprint (https://t.co/U24TUSseNr)! Our review unveils a revolution in genomics analysis with Genome LLMs. 🧬
🔍 What's Inside:
✅ The power & challenges of transformers in genomics.
✅ Cutting-edge models like HeynaDNA and scGPT & their impact.
✅ Deep dives into Enformer, DNABERT, and other Genome LLMs.
🌍 Why it Matters:
1. GPT-4's influence reshapes AI in genomics.
Unmatched insights into transformers' role in genomics.
2. Critical analysis of new models, addressing interpretability, privacy, & computational needs.
3. Essential for computational biologists & computer scientists to navigate the future of genomic data analysis.
This is a work led by the amazing PhD student, Mica Consens, in the lab! Also, a huge collaborative work with lots of field leaders @fabian_theis@genophoria@MKarimzade@michaelwainberg and Alan Moses!
@UofT@VectorInst@UofTCompSci@UofT_LMP@UHN@pmcc_ai@UHNAIHUB
The question of what makes us human remains enigmatic, but we investigate how enhancer hijacking, or fondly, "HARjacking", may have played a role in human-specific genome evolution in our study now out in @ScienceMagazine ! https://t.co/abm1c7LdAO
11 ways ChatGPT saves me hours of work every day, and why you'll never outcompete those who use AI effectively.
A list for those who write code:
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really nice review by @fabian_theis group on thinking about predicting the impact of perturbations and the promise of single cell omics and ML for this: https://t.co/VUgAXhkeN7 Also comes with a nice GitHub page of resources.
Graph neural networks and transformers taking advantage of contextual information and large unannotated multimodal datasets are redefining what is possible in computational medicine.
https://t.co/nvxxkAPHvf
Doing #SingleCell#RNAseq? Ever wonder if all those clusters are real? Turns out most feature selection & clustering pipelines can't tell when there's only 1 cluster! But I found a solution! 🧵👇
AI is going to permanently change how marketing works.
If you're not paying attention, you're going to be out of a job pretty soon.
I played around with ChatGPT (a new AI tool) recently.
Here's how AI will change marketing forever:
Our work on the interpretation of allele-specific chromatin accessibility using cell state-aware deep learning is online in advance @genomeresearch!
Wonderful joint work with @kalender_atak in the @steinaerts lab.
Link to paper: https://t.co/wBsGLyIhMg
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We are thrilled to announce the launch of the Eric and Wendy #SchmidtCenter. Merging biology and machine learning to understand the programs of life, the Center will enable a new field of interdisciplinary research aimed at improving human health.
https://t.co/CuPENZPDzQ
It can be a daunting task to construct regular expressions, especially complex ones.
The {rx_} function family from {RVerbalExpressions} 📦 makes this more accessible by allowing one to construct regex using verbal expressions 🔡
https://t.co/5G77171gYA
#rstats#DataScience
Making music with @1000daysband and listening to others' music has been my fuel for many outbreaks. Here is our latest tune afer an exceptionally hard year for so many. This is for you -- Don't Count Me Out https://t.co/0cz5U5mkgj
How do human promoters sense genomic context to control gene expression?
Exciting study from @BarakACohen integrating hundreds of promoters into different loci
Promoters are broadly compatible with activation in different contexts
https://t.co/K4rOgtVVmg
Our paper describing ArchR, a single cell analysis platform designed for scalable analysis of open chromatin data, is out in Nature Genetics. Congrats to Jeff and Ryan!
https://t.co/818T6S3ff5