@bdermanmd MRD based stopping maintenance
- makes a strong case for stopping in MRD neg- sustained MRD neg, no HR features, PET neg
- but we should and can stop earlier with effective Rx. we should think about this more
#ASH25
Very honored to have received the @PCF_Science Young Investigator Award!
Incredibly grateful for my mentorship team led by @TDorffOnc! Also thankful for all my current and past mentors/teachers for the support.
@cityofhope@cityofhopeoc
Honored to share our newly published manuscript https://t.co/xAH8RPTQNf which demonstrates that circulating tumor DNA (ctDNA) by PhasED-Seq offers the most precise definition of remission after frontline therapy for patients with large B-cell lymphoma (LBCL) out now in @JCO_ASCO. #ctDNA detection of #MRD. 1/18
The SUNMO trial manuscript is now published at @JCO_ASCO! Mosun-Pola is superior to RGemOx in patients with ref/rel LBCL with 3X progression free survival and 2x complete response rates. Only 4% had CRS more than a fever. #lymsm@elizabeth_budde
https://t.co/7u02KikJmE
Treatment can be difficult, and everyone finds something that helps them get through. For grateful patient Ray Hartjen, it’s music. Listening, composing and playing takes him to a place of peace, even on the hardest days, and reminds him there is still beauty, light, and hope. 💙
@DoctorAKrishnan is an amazing mentor, colleague and a leader of the City of Hope Myeloma @cityofhopeoc program and a national leader. Very pleased she is the SWOG chair and looking forward to the collaboration.
1/ Excellent news for 🇺🇸 patients receiving CAR-T therapy!
FDA has listened to data and relaxed CRS monitoring and driving restrictions for liso-cel for #lymsm / ide-cel for #MMsm.
Huge step to lower time toxicity and disparities.
Can this be fixed for all CAR-T products?
I joined @cityofhope when our world-class #HelfordHospital in #Duarte opened 20y ago. Then, I had the honor of seeing the first pts at our #NewportBeach site 5y ago & then our #Irvine site 2y ago. Soon, our @cityofhopeoc hospital will open. A truly momentous occasion that will bring state of the art oncology care to #OrangeCounty - today’s key ceremony was the beginning of that chapter!
Amazing response rates with trispecific antibody JNJ-5322 in RR MM. N. van de Donk suggest it is as effective as BCMA targeting CART. In fections are still quite high. All patients should get prophylactic IgG replacement. 12 months PFS of 95%. Prophylactic toci significantly reduced CRS, no ICANS seen.
#ASCO25
Amrita Krishnan, M.D., our executive medical director of hematology, has hope after witnessing remarkable progress in myeloma treatment—helping patients achieve dreams, from weddings to graduations.💙
What gives you hope? We'd love to hear! 💬
Learn more:https://t.co/f83Cls53KB