Dev Majumdar

Majumdar Lab. Fun with B cells and RNA. Here to help anyone doing science.

[Anshul Kundaje @anshulkundaje]

@bioalgorithmist I'm not referring to any particular tool. I'm referring to how scientists are presenting their science and that of others. It's getting so bad that it's impossible for any non-domain expert to believe anything anyone claims. This is extremely troubling for credibility of science.

[Anshul Kundaje @anshulkundaje]

Excellent example of the core issue I was trying to get at wrt "virtual cells" - optimizing a prediction objective will not necessarily provide an accurate representation of physical or biological phenomena. It's extremely important to be very clear about this. 1/

[Dev Majumdar @BcellD]

It was a dark time in the pre-Benchling era in my "ecosystem." Worth noting that people who say this exist. Long live @benchling and props to their VCs.

[Alfredo Andere @AlfredoAndere]

Huge respect and admiration for Benchling, but I cant take one more vc telling me about their “strategy” of being free for academics and then selling to them once in industry. That was a mistake! Later re-packaged into a cute story that is very hurtful to our ecosystem.

[Dev Majumdar @BcellD]

@Jeff_Mold I am so mixed on this alternative, its funding and findings. But it beats streptozocin injection in mice. Both are perhaps false choices. https://t.co/6VIeOBzs9r

[luba luft @luba_loop]

TIL the best way to spread misinformation is by presenting it in LaTeX

[Osama Harraz @OsamaHarraz]

✅ @Harraz_Lab has an open lab technician position ✅
Highly motivated individuals with relevant experience are encouraged to apply.
https://t.co/ac0ZXzvaQb

📢 We explore brain blood flow, physiology and pathophysiology of ion channels. Learn more https://t.co/xKpn4iy0ct

Plz RT

[beets @0beets]

NYC's public college system paid Oracle ~$600M to build our course management portal. It's built on top of Oracle's PeopleSoft suite, which they refused to customize without an extra $400M (to hit $1B).

New Yorkers got the image below and pay $5M+ / year for *hosting*.

[Dev Majumdar @BcellD]

@TheBrysonLab Znf207 hit is totally fascinating/enigmatic!

[Dev Majumdar @BcellD]

@pkafka @semaforben @kimmasters @JamesStewartNYT Sherman managed to cover a lot of it, minus the Chapek and Bay confirmatory interviews! https://t.co/jhgUKfh9td

[Alex Sherman @sherman4949]

Seems like a good day to re-up this one from last year - almost to the day!

https://t.co/BucqdWfpW2

[Jeremy Baskin @basktastic]

Fascinating study @NatureComms from @RohacsTibor showing that phosphatidic acid can regulate PIEZO2, the mechanosensitive ion channel — and so glad to see yet another application “in the wild” of optoPLD, @ReikaTei’s optogenetic membrane editor for phosphatidic acid! #lipidtime

[Dev Majumdar @BcellD]

The best clickbait is google images molecular clickbait. How else do you read a calcium signaling paper with a "Parabolic Flight Experimental Design" methods section. https://t.co/kyvj510nrw

[Viviana Risca @vivrisca]

Tried to express and purify your own Tn5 transposase only to run into stability or activity issues? Our new @biorxiv preprint describes OpenTn5: a robust, high-yield protocol for producing a stable pG-Tn5 transposase fusion. Spearheaded by @Jan_Soro.
https://t.co/5BPTAQCBkh

[Dev Majumdar @BcellD]

Incredibly cool. And now all I can think about is making homemade flag M2 antibody...

[Joost Snijder @joostsnijder]

Our paper @MFPronker @JWBglnk on the structure of anti-FLAG-M2 in complex with the FLAG-peptide (DYKDDDDK) is now peer reviewed @JMolBiol 🎉
https://t.co/kBum4BWpu3

[Brewster Lab @BrewsterLab]

We posted a new preprint (https://t.co/054qrUypVC). We've been thinking about how to characterize TF function. One challenge is that function and occupancy are difficult to disentangle. We use a simple model and a simple system to test how promoter features change function.

[Stamford Sam @Stamford_Sam]

@dieworkwear Some can pull it off

[Dev Majumdar @BcellD]

@BryanHeit Uninformed spectator here, but like... no gloves necessary?

[Balazs Lab @BalazsLab]

We are looking for postdocs interested in working on this project to engineer polyclonal vectored antibody delivery!

[Dev Majumdar @BcellD]

I think this is my new favorite African livestream. Currently two lions playing as a rhino dozes nearby. https://t.co/bXSSwdeCs1

[Nick Klug @Nrklug]

I am recruiting graduate students, postdocs, and research staff. The future of vascular physiology research is bright, and I'm excited to fill the space with amazing people & discoveries.

[Dev Majumdar @BcellD]

@Jeff_Mold I remember a PNAS paper, but this seems to do it too! Very much OG single cell work... https://t.co/aGokrWEVPN