Very happy and proud to share our preprint on biorxiv where we describe two distinct mechanisms of nuclear and mitochondrial transfer RNA 3’ maturation. Thread below.
This is exciting! A platform to share small and unpublishable results will be immensely helpful to the scientific community to minimize research waste and address the reproducability crisis. #ResearchAgora#OpenScience
Let’s make peer review work for research!
Traditional peer review is:
🔸 Opaque
🔸 Uncredited
🔸 Unrewarded
🔸 Slow
✨ Peer review at Research Agora:
✅ Transparent
✅ Recognized
✅ Earn tokens
✅ Fast
💬 How would you like peer review?
https://t.co/LePOBcR1lv
The peer-reviewed version of our paper on human tRNA 3' processing is now published in @NatureSMB. Many thanks to the reviewers for their constructive comments!
https://t.co/CckIvTOOxX
See also the very nice related work by @BMartinHallberg@no1gv: https://t.co/FOcw8tVQv0
PhD Opportunity - I am recruiting a student to investigate mechanisms of co-transcriptional RNA processing in human mitochondria. This is in collaboration with @hauke_hillen and is funded by the DFG @dfg_public .
Deadline 3 January 2025. Apply below⬇️:
https://t.co/RjEiEglqki
Super excited to share our latest work on the native in-cell organization of the mitochondrial respiratory chain 🥳
Using cryo-electron tomography🔬, we show how the respiratory complexes (and other complexes) are organized inside native mitochondria!
https://t.co/cxHl1j20CJ
Join us in welcoming Isaac Fianu as our newest Assistant Prof. of Biochemistry!
The Fianu lab hopes to provide understanding of the spatiotemporal control of gene activity & elucidate fundamental mechanisms of systems coordination between transcription, DNA replication & repair.
Happy to share the latest preprint from our lab led by our very talented postdoc Fernanda Sala! We determined structures of the Nipah Virus RNA polymerase complex in its apo state and with template and product RNA bound during early replication!
https://t.co/RwbFClANvT
Our paper out today @nature: phages reconstitute NAD+ to counter bacterial immunity
Phaged invented a new biochemical pathway for NAD+ synthesis - including previously unknown enzymatic reactions - to evade bacterial defenses
Congrats @IlyaOsterman!
https://t.co/JuzwDHmlFU
I am excited to join @CaltechCCE@Caltech as an Assistant Professor this November!
The Fianu Lab will be a welcoming space for anyone interested in gene activity and genome stability. https://t.co/k8yDZZwsCT
We are looking for team members at all levels—please reach out!
Deadly kiss of polymerases: How Influenza polymerase cleaves capped nascent RNA from host Pol II to start its own transcription. Preprint from Alexander Rotsch et al. with Steven Cusack‘s lab @EMBLGrenoble.
https://t.co/DlT9iyvbUZ
If you want to work in biotech, but don't know what to work on: You should work on plants.
Why? A few reasons: Plants account for 80% of all biomass on Earth, there's a low ratio of researchers relative to possible impacts & more.
In this thread, I'll try to convince you. 🧵
How many different things can you grab using a small β-barrel? Sugars, #DNA,#RNA,#tRNA? All of the above. Led by Aline Umuhire Juru, Rodolfo Ghirlando @NatureComms, we find a class of OB-folds in Trbp and Arc1p recognize tRNAs by their universal 3’ ends. https://t.co/dJCbd7Z7Mo
We have an ERC-funded postdoc position to investigate the fine architecture of #Drosophila nervous tissues by cryo-ET 🪰
Looking for highly motivated candidates with strong background in fly cell biology 🫵
https://t.co/46JL864XJ7
#PhD, #DnD(?) & #postdoc positions in “theory and methods for non-equilibrium atomistic simulations of complex #biomolecules” – Interested in theoretical and computational #biophysics? Check out the #JobAlert & apply here ⬇️: Shares welcome! #hiring#job
https://t.co/ZJF97wtVnJ
The Hill-Maini lab website is live @bioe_stanford@Stanford. We are hiring for multiple postdocs who are excited about synbio/food/sustainability in filamentous fungi and building an inclusive and lab culture that fosters creativity! Spread the word!!!
https://t.co/1A1PfQXJCx