Bittersweet time of the year. Just finished exent with 2 of my amazing senior fellows there in their last week of fellowship!! 2 other amazing graduates also finishing. Will miss you!
Honored to have led our introductions, icebreaker and the Fellow's Panel with @SGO_org LEAD! The future is bright! Excited to co-chair with Kristy Ward next year! @ChrisDagherMD#representationmatters
In FIGO stage I endometrioid endometrial carcinoma, discordant-grade tumors that are initially high grade on biopsy and lower grade on hysterectomy behave more aggressively compared with concordant low-grade tumors. @tsialater@leitaomd
https://t.co/0nw1i3yWf0
So thankful for the opportunity to present at my favorite conference @ESGO_society in Denmark. Had the best time and had to rep my @ENYGO_official famiglia today in the OR as I process missing them until next time!
Time to re-assess value and cost of "routine" imaging in low grade endometrial cancer. CT and MRI are of low value in most low grade endometrial cancers.
https://t.co/CT9jItLzsG
Positive peritoneal cytology = not so “low risk.”
In stage IA G1 endometrioid EC, it doubled progression risk (aHR 2.6) and tracked with ARID1A loss.
🧬 Gynecologic Oncology (2025)
🔗 https://t.co/NHIxeAYP7K
@gyncsm@oncodaily@TeamEndo_MSK@gynoncjnls
The OncoAlert WEEKLY RoundUp 🚨
Covering the TOP of the week Sept 26-Oct 2, 2025
REGISTER at https://t.co/QFM2SYXqbg OR https://t.co/hwvqbilbLO
Discussing:
🫁 #LungCancer/ Immunotherapy
✅Dual CTLA-4 + PD-L1/PD-1 Blockade Shows No OS Advantage Overall but Boosts Outcomes in PD-L1–Low & STK11-Mutant NSCLC
✅Neoadjuvant/Perioperative Immunotherapy Outperforms Adjuvant in Resectable NSCLC, Even in PD-L1–Negative and Squamous Tumors
🩺 #BreastCancer
✅Trastuzumab Deruxtecan Outperforms T-DM1 in High-Risk HER2+ Early Breast Cancer (DESTINY-Breast05) NEWS FROM INDUSTRY
✅Adjuvant Ribociclib + Aromatase Inhibitor Maintains 4-Year iDFS Benefit in HR+/HER2– Early Breast Cancer (NATALEE Trial)
✅Sacituzumab Govitecan: Effective for Advanced TNBC & HR+/HER2– Breast Cancer With Practical AE Management Strategies
✅Higher BMI Amplifies Postmenopausal Breast Cancer Risk—Especially in Women With Cardiovascular Disease
GI / #GastricCancer
✅Early-Onset Transient Gastritis Common With First-Line Zolbetuximab in CLDN18.2+ Gastric Cancer
✅CLDN18.2 Expression in Gastric Cancer Is Dynamic During Chemoimmunotherapy, Linked to Immune-Inflamed Stroma and Outcomes
🧬 GU / #ProstateCancer
✅Prostate Cancer Germline Testing: Phone or Physician Counseling Boosts Satisfaction; Asian American Men Report Lower Satisfaction (PROGRESS Registry)
🧠 Mental Health / Survivorship
✅Cancer Survivors Use Antidepressants and Anxiolytics More Than Noncancer Peers—With Persistent Racial and Insurance Disparities
🧠 Gyn / #EndometrialCancer
✅“Aggressive” Histology Predicts Prognosis in Surgically Staged, Clinically Uterine-Confined Endometrial Carcinoma
@DiFedericoMD@doctordegio@StephenVLiu@bmassutis@faiska_hsk_skt@ErikaHamilton9@DrSAHaddad@AlexisLeVee@ArmandOrlandi@jamecancerdoc@JAMAOnc@DrRishabhOnco@Onco_Cifu88@drlopezgalindo@Dr_ElvinaA@JournalCancer@CACancerJournal@HFreisling@IARCWHO@drjkahn@DraMartinezLago@KoheiShitara@zaidheartsci@JAMANetworkOpen@realbowtiedoc@Duke_TORCHE@leitaomd@ChrisDagherMD@masharii3@matteolambe@Icro_Meattini@hoperugo