When we discovered irisin in 2012 (Bostrom et al), we described its actions in terms of the browning of the white fat and anti-diabetic effects. Here, in collaboration with the Mathis lab, we re-examine this in mechanistic detail. https://t.co/qDVrwgiGuM
The last piece of my PhD work is online 🥳
Multi-scan structured illumination microscopy for rapid and efficient volumetric super-resolution imaging
https://t.co/tWYNtqCSyT
#FBF to our Hem/Onc Translational Research Retreat last week! A day spent brainstorming transformative, interdisciplinary team science ideas/opps across campus, academic-industry partnerships, & recruitment! w/ @ChicagoITM@UChiPritzker & Ctr for Chemical Biology & Therapeutics
Ergothioneine is an atypical amino acid to which many health benefits in humans have been ascribed. Here we determine the direct protein target of ergo binding and how it functions in mitochondria and exercise. https://t.co/rzAKrmH78e
Does the lack of correlation between PGC1a RNA and protein give you a headache? Us too. Phillip Dumesic has uncovered a key factor controlling PGC1a mRNA translation https://t.co/AQWWz1u6jj
At 4pm on Tues 1/28, DFCI's Seminars in Oncology speaker is CB's @LabSpiegelman! His talk for the 2025 Emily Frederick DiMaggio lecture is entitled "The irisin/PGC1a pathway links exercise to resistance to cancer & neurodegeneration". Hosted by @puigserver_lab. Don't miss it!
Mitigating racial bias from LLMs is a lot easier than removing it from humans!
Can’t believe this happened at the best AI conference @NeurIPSConf
We have ethical reviews for authors, but missed it for invited speakers? 😡
Having trouble getting good preparations of extracellular fluids for proteomic analyses? We have published a detailed protocol, with step by step considerations, applicable to several tissues. We hope it is helpful!
https://t.co/LE2117MPI1
New preprint from the lab is online! The product of a stellar collaboration with @Muir_Lab, we explore a chemically defined physiologic media formulation based of the metabolite of tumor interstitial fluid (TIF, or “tumor juice”) and its effects on T cell function! A brief 🧵1/
Congrats to the everyone on both awesome teams who tracked down this new way tumors metabolically talk to T cells, including @ChufanC and @hardikshah42 at UChicago. And a big thank you to @CancerRF and the Brinson Foundation who supported our team in these studies.
My PhD thesis defense is scheduled on Tuesday May 28, 11am CST at BSLC 115, UChicago!
All are invited. DM me if you would like to join via zoom❤️
Title: Developing Novel Snapshot Multi-dimensional Structured Illumination Microscopy
https://t.co/PLB3i9LVkR