Anna Cichonska

Director of Data Science & Head of European Operations @HarmonicDiscov | Optimist | Passionate Traveler

[MIT Jameel Clinic for AI & Health @AIHealthMIT]

🗝️The right drug molecule will bind to a protein to treat a disease. But what about "undruggable targets"? #JClinic PIs @BarzilayRegina & @MarzyehGhassemi co-authored a new paper in @NatureBiotech w/ 15 co-authors on how AI could challenge drug design.
https://t.co/IewlHEAeRj

[Nature Communications @NatureComms]

@HarmonicDiscov, @rayrah_, and @CichonskaAnna present a method that enhances compound bioactivity modeling by integrating diverse data types, enabling cost-effective training data generation.

https://t.co/tobrltzEKl

[Harmonic Discovery @HarmonicDiscov]

Excited to share our paper published in @NatureComms led by @rythei & @CichonskaAnna!
By integrating diverse bioactivity datatypes, we built a best-in-class drug-target interaction model called Kanopy—achieving an experimentally confirmed prospective hit rate of 40% (at 1µM)!

[Harmonic Discovery @HarmonicDiscov]

We are thrilled to announce that we are in-licensing an asset developed by Professors Hong-Yu Li, PhD (previously of UAMS) and Neil Shah, MD PhD (UCSF) for FLT3 mutant AML! Learn more in our press release below!
https://t.co/Ti6x1cySFy

[Harmonic Discovery @HarmonicDiscov]

Congratulations to the HD team for their newly published article! We are strong supporters of the peer review process and aim to have all of our public work in great journals.

[Harmonic Discovery @HarmonicDiscov]

Also at #ACSFall2023 check out our talk on leveraging 3D features derived from AlphaFold2 structures to improve protein-ligand affinity predictions!

[Harmonic Discovery @HarmonicDiscov]

Excited to share DockDB to the public! DockDB is a an all-inclusive Relational Database Management System (RDBMS) for molecular docking experiments. Find out more at our blog post here, we are also presenting more at #ACSFall2023 https://t.co/NdnRRo3cgR

[Harmonic Discovery @HarmonicDiscov]

We are thrilled to share early work on leveraging AlphaFold2 to explore the conformational diversity of kinases! This work was led by led by @carmenmasri and Francesco Trozzi. A poster was presented last week at @workshopmlsb. Please take a look here:
https://t.co/q01n0ZZTyC

[Innovation Endeavors @iendeavors]

Announcing our investment in a team that embraces the complexity of kinase therapeutics — @HarmonicDiscov. Once considered undruggable, kinases are critical nodes in oncology and inflammatory diseases + are involved in functions like cell growth/survival. https://t.co/WEtGmmCZie

[Anna Cichonska @CichonskaAnna]

I’m thrilled to be a part of this journey!

[Harmonic Discovery @HarmonicDiscov]

We are thrilled to announce our $8M seed financing lead by @iendeavors along with @fiftyyears @ycombinator Boom Capital and @caffeinatedcap! We are also excited to announce that @jdudley will be joining our Board of Directors!
https://t.co/e5LkEaXMiZ

[Harmonic Discovery @HarmonicDiscov]

It's hard to find a good mentor. We are extremely grateful for having the opportunity to participate in the JPALS program and to be part of the @JLABS ecosystem of companies!

[Nature Communications @NatureComms]

Results of the IDG-DREAM Challenge comparing algorithms to predict kinase inhibitor activities @CichonskaAnna @allawayr @dr_e_a_m @Sagebio @DruggableGenome @csaalto @HIIT @FIMM_UH @Oslounivsykehus @OCBE_UniOslo @OusResearch @gururavikumar1 @WennerbergLab
https://t.co/66apsu2m5t

[Anna Cichonska @CichonskaAnna]

@maciejbanach 🇵🇱

[Anna Cichonska @CichonskaAnna]

@yk_tani Congratulations, Yosuke!! 💪🏻🎉

[Nightingale Health @NgaleHealth]

Nightingale has entered into a service agreement with Mitsui & Co.’s fully owned subsidiary (Welltus Inc.) to sell health and well-being services in the Japanese market.
Read more: https://t.co/qH9zyZlzyi

[Anna Cichonska @CichonskaAnna]

@helijulkunen @PeterWyrtz @NgaleHealth @uk_biobank @helijulkunen you’re amazing, too! Hope to continue working together for a very long time!

[Anna Cichonska @CichonskaAnna]

@PeterWyrtz @NgaleHealth @uk_biobank @helijulkunen @PeterWyrtz, you are the real super star! Happy to work at @NgaleHealth and learn from you!

[Antti Kangas @anttikan]

Based on scientific findings, @NgaleHealth will launch a screening tool for detecting those at high risk for getting severe symptoms if infected by #coronavirus. The risk estimate is based on molecular signatures in blood.

https://t.co/ta8O9Xo03V

#prevention #COVIDー19

[Teemu Suna @teemusuna]

What happens once the central banks’ trillions are spent? More trillions? This is not a long-term solution. We need to prevent shutdowns while still slowing down the virus outbreak. #covid19 https://t.co/PrkGngrqxR

[Nightingale Health @NgaleHealth]

The reason why we've cancelled bookings at Nightingale Nest for the next weeks.

#CoronaOutbreak #FlattenTheCurve #prevention #StayHealthy

Hopefully, the situation stabilises & we all go back to our regular schedules soon.

📊source: @nytimes