Postdoc @UZH_en, Evolutionary Genetics, Human population history, Genome-wide variation and cultural variation; formerly @institutpasteur & @MPI_EVA_Leipzig
Our genomic research of Taiwanese Austronesians is now out in @PNASNexus! We study and leverage the diversity in Taiwan to understand better the genetic profiles of early (pre-) Austronesians, who moved into and out of Taiwan.
https://t.co/enLWibwN1h
🧵:
In our lastest paper in close collab with Wibhu/Dan/Mark, we have traced the genetic origin of modern Austroasiatic speakers of MSEA to ancient ones, and identified key genetic diversifications among populations associated to various AA language branches!
https://t.co/N4zEiHmzWp
Some new exciting metabolomic work from @NgaleHealth using UK Biobank data 🔽
Metabolomic data for the full UK Biobank cohort will be made available to all researchers as part of our upcoming data release next month.
https://t.co/86tiXeDSuO
Linguistic features seem to spread faster in farming societies.
Mean diffusion rates across time for agriculturalist (AFR) vs hunter-gatherer (HG) languages
Our method for posterior sampling of Ancestral Recombination Graph, SINGER, is now published at @NatureGenet: https://t.co/jQwazbsZ70. Come and check it out! Here is our previous Twitter thread with detailed explanations of the work.
📣Online NOW!
📄Estimation of demography and mutation rates from one million haploid genomes
🧑🤝🧑 @jgschraiber@DocEdge85 & co
https://t.co/Z9HINb5mYT
Given two genomes, can you tell who’s taller or more prone to a disease? How confident can you be? A fresh take on phenotypic inference, now out in @NatureComms :
https://t.co/c8o4oHyWhw
See thread🧵👇:
Happy to share that our work from the @nmancuso_ lab is out in @NatureGenet! We developed SuShiE, a multiancestry fine-mapping method for molecular traits. https://t.co/8gySuJkDEw
Ancient #DNA reveals #Papua New Guinea's genetic past. Study @NatureEcoEvo by an intl. team led by @KathrinNaegele@MPI_EVA_Leipzig shows the significance of regional dispersals and local interactions in coastal Papua New Guinea. https://t.co/HQwH2FJSBq & https://t.co/06zruI6CoU
Our new paper is out in @ScienceMagazine! By exploring the rich genetic diversity of Brazil, we show how fine-scale genomic analyses reveal that this diversity, rooted in Indigenous ancestry and centuries of complex demographic history, plays a key role in population health.
The fifth paper from the group this year. Led by a former postdoc @imyingchulo, our evaluation of polygenic scores (PGS) for BMI and T2D for Native Hawaiians is published in @CommsBio!
https://t.co/LpuPI02KvG
Why Polynesians’ high risk of metabolic disease? @Dang_Liu tests thrifty genotype vs population adaptive patterns (incl % Austronesian & Papuan ancestries), demographics (strong bottleneck in Eastern Polynesians!). Results: both!! BMI thrifty, HDL & others under drift & more!! 🤩