Ribosomes are often found translating small ORFs outside of canonical protein-coding regions - but why? Here, we examine how variant allele frequencies in non-canonical ORFs (ncORFs) compare to those in known coding regions of the genome @YosephBarash
https://t.co/dRJMIAmQfx
We were told to wait at the airport for a second crew to resume our journey. 4 hours later they told us that, in fact, the flight was cancelled. No overnight accommodations, offers for reimbursement, or travel vouchers. Absolutely shameful.
@AmericanAir this morning our flight was delayed due to being "overweight" and 4 passengers were involuntarily removed. Then, halfway to our destination, we were diverted home because there wasn't enough fuel for the aircraft to make a round trip without stranding the crew...
Congrats to @CAMBUpenn MD/PhD student @DanielAkuma5 and all the members of the @UPenn team that developed the SANIPACK N95 portable UV-C sterilizing device to extend life of N95 masks! Check it out on pp. 71-73 of @AmerMedicalAssn Impact Challenge: https://t.co/fJFcsteCqU
I’m thrilled to share a major portion of my PhD work, now out in @NatureMedicine, in which we associated rare loss-of-function variants on an exome-wide scale with various clinical phenotypes captured in the EHR to uncover new gene-disease relationships! https://t.co/bLSiRjBLYF
About 50% of the US biomedical workforce is foreign born. It has been a hard 4 years (especially the last one). This Thanksgiving I am specially grateful for their grit, persistence, optimism and amazing achievements! And of course for the country that welcomes us !🦃
Here I explore some strange aspects of the data set used in the problematic AlShebli @NatureComms paper. See Section 13 'Summary'. How can one have a set of mentors with an average age > 200? How can one have 91 mentors? Always always graph your data!
https://t.co/peDVXyuJbJ
Finally got through the ridiculous @NatureComms paper. One of my favorite lines:
"Whenever a junior scientist publishes a paper with a senior scientist, we consider the former to be a protégé, and the latter to be a mentor..."
What a warped view of collaboration.
okay... *deep breath*... I believe deeply in academic freedom... but the analyses presented by the authors are *horrendously* insufficient to support the conclusions that are reached
We have now published an Editor’s Note on this paper https://t.co/TCxHlFThh6 to alert readers of our ongoing investigation. We will post further updates as soon as possible.
Back to science ! Happy to introduce our newest preprint from our lab @XinSheng7 Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments https://t.co/uB0wNx7WzK