Beyond happy to see our latest publication out in @Hemasphere_EHA
https://t.co/iIoDigoxEA
We show that all human macrophage feeders activate JAK/STAT and MAPK signaling in CLL cells to support leukemic persistence.
Grateful for our team effort and the SFB-1530 for support
Time for a quick read? Check out our perspective on TiME interactions in CLL and RT! Fun discussions with Phuong-Hien Nguyen and Alex Vom-Stein!
https://t.co/HMd5VHuJKh
🆕🆕🆕Preprint from our labs
https://t.co/xzSLspTE4x
In this brief report, we evaluated various macrophage coculture systems for their CLL-feeding potential, phagocytosis capacity, induction of treatment resistance, and their impact on the transcriptional profiles of CLL cells
Beyond excited that the first paper of my PhD journey is out in @NeuroOnc today, reviewing the brain metastatic immune microenvironment.
Super grateful for the great collaborative effort, particularly the guidance of @DimHien and @RolandGoldbrunn !
https://t.co/4GxktINN0H
thrilled to share our accepted Review in @NeuroOnc. The 1&only @luca_david_ kicks off his PhD with a comprehensive overview of the Immune Landscape in Brain Metastasis. So grateful for the support from all partners, esp. the guidance of @RolandGoldbrunn.
https://t.co/kGi3wShny5
Excited to share our @lewis_ri_@HallekMichael perspective on double-refractory (2R) #CLL, now in @BloodJournal. 2R pts are a growing challenge with poor outcomes. We outline the current landscape and explore targets in the tumor microenvironment. #CLL
https://t.co/ieipPnPSYJ
Great pleasure to present our work on the role of RIPK1 in beta cell survival! Congratulations @onayyveli for this amazing piece of work. Thanks a lot to our collabs especially to @CardozoKupper@sfb_1403@CECAD_@UniCologne
As promised, the second issue of our CLL review series is out now at Seminars in Hematology. Check it out if you are interested in CLL biology and mouse models!
https://t.co/AEJ44ETzS8
For 25 years, the Toll-like Receptor pathway was considered a series of distinct protein complexes that drive inflammation. Today, we report that the entire pathway, from receptor to transcription factor, is executed from within one complex—the myddosome.
https://t.co/J9xnnt0xXD
📢Our latest review is online! We discuss how macrophages influence CLL progression and frontline therapy response, a topic initiated and contemplated by our youngest lab member @hjestrabek. Such a great joy for me to work with the new Gen of 2000s 🎉
https://t.co/pr1jZw6jqO
My huge congratulations to Sumiya, Shaista and Sanjay for this very nice publication!! We are so thankful to be involved and it was so lovely to be able to follow how the challenge of encapsulating hydrophobic drugs such as kinase inhibitors could be tackled elegantly here.
Addressing the challenge of hydrophobic drug delivery! Our latest research on lipid-coated silica nanocarriers showcases a novel approach to prolonging the release of hydrophobic drugs, promising enhanced treatment efficacy with controlled delivery🧬💊 https://t.co/xoJdOxNZ3N
Thrilled to share our characterization of the human tyrosine kinome.
Try out the public website: https://t.co/a5zfETTzCf
Wonderful collaboration with @CantleyLab@benturklab@LabYaffe. Many years of work led by Jared Johnson!
https://t.co/UsmA3wE78P