Hien Nguyen

Cancer biologist interested in the tumor microenvironment, cell-cell interactions, signal transduction, protein kinases, and kitty cats

[Hien Nguyen @DimHien]

Beyond happy to see our latest publication out in @Hemasphere_EHA
https://t.co/iIoDigoxEA
We show that all human macrophage feeders activate JAK/STAT and MAPK signaling in CLL cells to support leukemic persistence.
Grateful for our team effort and the SFB-1530 for support

[Elisa ten Hacken @etenhacken]

Time for a quick read? Check out our perspective on TiME interactions in CLL and RT! Fun discussions with Phuong-Hien Nguyen and Alex Vom-Stein!

https://t.co/HMd5VHuJKh

[Hien Nguyen @DimHien]

🆕🆕🆕Preprint from our labs
https://t.co/xzSLspTE4x
In this brief report, we evaluated various macrophage coculture systems for their CLL-feeding potential, phagocytosis capacity, induction of treatment resistance, and their impact on the transcriptional profiles of CLL cells

[Luca Schreurs @luca_david_]

Beyond excited that the first paper of my PhD journey is out in @NeuroOnc today, reviewing the brain metastatic immune microenvironment.

Super grateful for the great collaborative effort, particularly the guidance of @DimHien and @RolandGoldbrunn !

https://t.co/4GxktINN0H

[Hien Nguyen @DimHien]

thrilled to share our accepted Review in @NeuroOnc. The 1&only @luca_david_ kicks off his PhD with a comprehensive overview of the Immune Landscape in Brain Metastasis. So grateful for the support from all partners, esp. the guidance of @RolandGoldbrunn.
https://t.co/kGi3wShny5

[Hien Nguyen @DimHien]

@poepsel_lab @MolecularCell @paulvictorsauer congrats Simon & Team 👏👏👏

[VomSteinA @vomSteinA]

Excited to share our @lewis_ri_ @HallekMichael perspective on double-refractory (2R) #CLL, now in @BloodJournal. 2R pts are a growing challenge with poor outcomes. We outline the current landscape and explore targets in the tumor microenvironment. #CLL
https://t.co/ieipPnPSYJ

[Hien Nguyen @DimHien]

@markessien @40PercentGerman when writing emails, I even deliberate over using „Sie“, „Du“ or „du“. Am I obsessed?🤔

[Hien Nguyen @DimHien]

@PeltzerNieves @onayyveli @CardozoKupper @sfb_1403 @CECAD_ @UniCologne congrats Nieves!! 👏👏👏

[Nieves Peltzer @PeltzerNieves]

Great pleasure to present our work on the role of RIPK1 in beta cell survival! Congratulations @onayyveli for this amazing piece of work. Thanks a lot to our collabs especially to @CardozoKupper

@sfb_1403 @CECAD_ @UniCologne

[Elisa ten Hacken @etenhacken]

As promised, the second issue of our CLL review series is out now at Seminars in Hematology. Check it out if you are interested in CLL biology and mouse models!

https://t.co/AEJ44ETzS8

[Vincent Alcazer @AlcazerVincent]

JAK inhibition enhances checkpoint blockade immunotherapy in patients with Hodgkin lymphoma | Science https://t.co/QUeSgIgsG4

[Jonathan Kagan @jkagan1]

For 25 years, the Toll-like Receptor pathway was considered a series of distinct protein complexes that drive inflammation. Today, we report that the entire pathway, from receptor to transcription factor, is executed from within one complex—the myddosome.
https://t.co/J9xnnt0xXD

[Hien Nguyen @DimHien]

📢Our latest review is online! We discuss how macrophages influence CLL progression and frontline therapy response, a topic initiated and contemplated by our youngest lab member @hjestrabek. Such a great joy for me to work with the new Gen of 2000s 🎉
https://t.co/pr1jZw6jqO

[Gianmaria Liccardi @Giammy_L]

Incredibly proud of our first paper in @cddpress on pMLKL-s345 . Congrats @c_kelep for driving this project. BIG Thank you to all our collaborators @ale_annibaldi81 @Linkermann_Lab @Walczak_Lab @PardoGalvez_Lab for your incredible support and input. https://t.co/DwjxyeCIId

[Hien Nguyen @DimHien]

@Giammy_L @cddpress @c_kelep @ale_annibaldi81 @Linkermann_Lab @Walczak_Lab @PardoGalvez_Lab congrats dear Giammy & Team!! amazing work 🎉

[Hien Nguyen @DimHien]

My huge congratulations to Sumiya, Shaista and Sanjay for this very nice publication!! We are so thankful to be involved and it was so lovely to be able to follow how the challenge of encapsulating hydrophobic drugs such as kinase inhibitors could be tackled elegantly here.

[Research Group Mathur @LabMathur]

Addressing the challenge of hydrophobic drug delivery! Our latest research on lipid-coated silica nanocarriers showcases a novel approach to prolonging the release of hydrophobic drugs, promising enhanced treatment efficacy with controlled delivery🧬💊 https://t.co/xoJdOxNZ3N

[Hien Nguyen @DimHien]

@PeltzerNieves @braegelmannlab @WalczakLab @LiccardiLab @JoanMonte @sfb1399 @UKKoeln Congrats Nieves and team!! Amazing paper!

[Michael Yaffe @mbyaffe]

Thrilled to share our characterization of the human tyrosine kinome.
Try out the public website: https://t.co/a5zfETTzCf
Wonderful collaboration with @CantleyLab @benturklab @LabYaffe. Many years of work led by Jared Johnson!

https://t.co/UsmA3wE78P