Dr. Goldoval

1

[SpaceX @SpaceX]

Intel is joining Terafab!

SpaceX, @xAI, and @Tesla are launching the most epic chip-building effort ever - combining logic, memory, and advanced packaging under one roof → https://t.co/512DIlqNgY

[Brian Roemmele @BrianRoemmele]

https://t.co/0XO4cfKFnJ

[Brian Roemmele @BrianRoemmele]

FASTER AI WITH JUST A SOFTWARE TWEAK?

Yes!

I may have just solved memory crunch and stalls on GPUs running AI, perhaps by 50% with 20%-30% lower energy costs.

The thing is, I wrote about it in 1988 in PC Magazine Lab Notes some folks liked it.

I am bringing the receipts:

[Peter H. Diamandis, MD @PeterDiamandis]

With AI & agents, people will be able to run companies with 20-40% fewer employees than they have today. 
But I wouldn't panic... We'll create 4-5x as many more companies, just like we've done with every other exponential tech.

[Edward Frenkel @edfrenkel]

Thank you, @ericweinstein! 🙏🤩 Well-said, and what a great question at the end!

My take: it all starts with us, humans. We create new technology, we "program the machines" so to speak. We set the stage. If we can cultivate this sixth sense of our deeper connection to each other (which is what my video is about!) - then new technological advances will likely bring us even closer together. That's my hope. 😃

[Dr. Alex Wissner-Gross @alexwg]

https://t.co/dHNitEtErG

[Elon Musk @elonmusk]

SpaceXAI Colossus 2 now has 7 models in training:

- Imagine V2
- 2 variants of 1T
- 2 variants of 1.5T
- 6T
- 10T

Some catching up to do.

[Dr. Goldoval @DoctorGoldOval]

@ericweinstein enough rope to..
enough string to string it a l o n g j us t a li'l furth err

[NASA Artemis @NASAArtemis]

"We will always choose each other."

Mission control has reacquired signal with the Artemis II crew after the mission’s planned loss of signal. Our astronauts are once again using the Deep Space Network to keep conversation and science data flowing between space and Earth.

[Bryan Johnson @bryan_johnson]

If you’re wondering how I initially landed at 20 minutes at 200°F for a daily dry sauna, this protocol is supported by both large observational longitudinal cohorts and smaller interventional studies. These studies demonstrate significant benefits for longevity and healthspan, including reduced mortality and morbidity from all-cause and chronic diseases.

Observational evidence suggests that using a dry sauna 4 to 7 times per week for more than 19 minutes per session at temperatures between 176F and 212F provides the highest level of health benefits.

Here are some examples of the benefits (using comparable protocols to mine):
> 14-40% reduction in all-cause mortality in middle aged men
> 48-70% long-term reduction in fatal heart disease in both women and men
> 47% Reduction in the risk of developing a high blood pressure in healthy men
> 31% average reduction in hsCRP in healthy middle aged men.
> 40% Long term sauna use was correlated with decreased all-cause mortality
> 48% reduction in dementia risk.
> Slightly improved well being, 83% reported better sleep, and 77% less risk of psychotic disorders.

Important points to keep in mind

While most dry sauna studies do not identify heat-shock response including HSPs, the ones that do only give directional hints of HSPs secretion, to our awareness intracellular expression of HSPs has not been addressed with dry and why I decided to start quantifying my heat shock protein secretion and expression myself.

While HSPs are a major driver of sauna benefits, other mechanisms including increased cardiac output and blood flow (exercise mimetic), vascular remodelling and adaptation, as well as sweating all contribute to the benefits.  A strong hit at this are the smaller yet significant benefits observed even with shorter durations and lower frequencies (10–19 minutes, 2–3 times per week), conditions very unlikely to achieve any measurable heat shock protein response.

Therefore, do not be discouraged if you aren't ready for the long sessions required for measurable HSP activation. Real health benefits begin with just 10 minutes at 176°F, twice a week.

If you are just starting your sauna protocol, remember that reaching longer sessions (over 33 minutes) at extreme heat of 190°F or above requires time. Listen to your body, and progress gradually and be careful not to exceed your personal heat tolerance limits. Also, stay hydrated and if you’re a man, ice your boys.

My benefits from my starting protocol were real and persistent over 232 sessions including

> 10+ years reduction of my vascular age and functional improvement (central pressure markers showing increased vascular elasticity and compliance)

> Full detoxification of 3 out of 6 environmental toxins, remaining 3 were slashed by 55% to 65%, one toxin was reduced by only 15% and persisted at a slightly elevated level (with 15 sessions only).

> Elimination of 85% microplastics from my blood and semen

> Fertility markers at all time high (count, motility, and morphology) in 24 iced sessions.

[Brian Roemmele @BrianRoemmele]

Closer to the Moon than Earth…

[Dr. Goldoval @DoctorGoldOval]

@karpathy good eye, THANK YOU

[Andrej Karpathy @karpathy]

New supply chain attack this time for npm axios, the most popular HTTP client library with 300M weekly downloads.

Scanning my system I found a use imported from googleworkspace/cli from a few days ago when I was experimenting with gmail/gcal cli. The installed version (luckily) resolved to an unaffected 1.13.5, but the project dependency is not pinned, meaning that if I did this earlier today the code would have resolved to latest and I'd be pwned.

It's possible to personally defend against these to some extent with local settings e.g. release-age constraints, or containers or etc, but I think ultimately the defaults of package management projects (pip, npm etc) have to change so that a single infection (usually luckily fairly temporary in nature due to security scanning) does not spread through users at random and at scale via unpinned dependencies.

More comprehensive article:
https://t.co/EJAZbqAPIQ

[Dr. Goldoval @DoctorGoldOval]

@PhilosophyOfPhy https://t.co/vuoCXMu8cF

[Carlos E. Perez @IntuitMachine]

Oh wow! Figure quit on the OpenAI collaboration.

[Dr. Goldoval @DoctorGoldOval]

@karpathy that is a bug not a feature
TERNARY > binary
because TERNARY provides for humility
I am not a switch

[Dr. Goldoval @DoctorGoldOval]

@doncmleon @Jeremybtc Coca-Cola's automated label printer accidentally printed their 100yo secret formula on a few cans that went to Walmart & before they could recall them a guy posted the recipe, now anyone with a soda stream..

[Blaze @browomo]

For 6 months I woke up at 5 AM to catch Asian markets on Polymarket. During that time I lost my girlfriend, gained 8 kg, and got used to drinking coffee instead of breakfast

Then I wrote an agent that monitors everything for me while I sleep. In the 1st month income went up 15% and I finally deleted the 5 AM alarm

Turns out a half-asleep human trades worse than a 200-line script

I thought discipline meant waking up early. In reality it was just stubbornness that cost me money and health. When I finally sat down to build the agent it became clear why

Here is what is under the hood:

1. Sentiment analysis powered by Claude. Every 15 minutes the agent runs a feed from 40+ Asian sources: Reuters Asia, Nikkei, South China Morning Post, Yonhap

2. NLP tone classification. It compares sentiment shifts to open markets on Polymarket through the API, and if the news has already dropped but the odds have not reacted yet that is the entry window

3. Kelly criterion. A mathematical formula for position sizing instead of my usual "I will bet more, feeling lucky"

4. A hard stop at 5% of the deposit per trade so that 1 mistake cannot kill the entire account

5. A cooldown between entries so the agent does not stack up a cluster of correlated positions

These are exactly the rules I was missing at 5 AM. I knew them perfectly well but consistently ignored them because on adrenaline and caffeine every bet felt like an "obvious opportunity"

When I ran a backtest on my old trades it was genuinely painful: 60% of the bets I placed by hand in a half-asleep state would have been rejected by the agent for failing the expected value filter

Those were the exact ones dragging the whole result down

When I was building my agent I needed a benchmark. A wallet that already trades on similar logic so I could compare my results to someone else's

Found 1 that works almost like a mirror of what I described: same Asian markets, same cold calculation without emotion. I still keep it bookmarked and periodically check how it handles the same situations: https://t.co/GKgiBNdq2Y

That is actually the wallet I started with when testing auto-copying through a bot before I launched my own agent. A useful thing if you want to see how a strategy works on someone else's example first and only then build your own: https://t.co/6oJMPDWj4z

[hoeem @hooeem]

https://t.co/KW3rQbdBJT

[Rimsha Bhardwaj @heyrimsha]

Explore it here: https://t.co/6PNRk8nItc