Sophie Dumont

Mechanics of cell division @UCSF

[Sophie Dumont @DumontLab]

Excited to share our work out in @CurrentBiology today! We find that NuMA acts as a spindle "glue" - independent of its partner dynein. Congrats to student Nathan Cho who led the work, and thanks to Merve, Aryan and @Yildiz_Lab for in vitro help. https://t.co/JVtGXoqvDl

[Sophie Dumont @DumontLab]

Excited to share NuMA preprint #2/2! We report structural and functional insights into how NuMA activates and regulates dynein at cell division. Congrats to Merve Aslan @Yildiz_Lab, @AmicoEnnio @Carter_Lab and Nathan Cho from our lab. And others inc. Maddie Blaauw from our lab.
https://t.co/3ac0zfQyDI

[Sophie Dumont @DumontLab]

Excited to share NuMA preprint #1/2! We find that NuMA mechanically reinforces the spindle independently of its partner dynein. Congrats to student Nathan Cho who led the work, with Merve Aslan and @Yildiz_Lab. https://t.co/CeBNxJPByv

[Sophie Dumont @DumontLab]

@alexandraflong Alex was a postdoc with Tim @StearnsLab & Jessica Feldman

[Sophie Dumont @DumontLab]

Congrats to Alexandra Long @alexandraflong, the second student from our lab to start their own lab! Her lab is in Univ. Kentucky's Biology Dept, studying the evolutionary cell biology & biophysics of cellular organization. Check it out! https://t.co/hYxwjZLLkr

[Sophie Dumont @DumontLab]

Excited to share our work out in @CurrentBiology ! We find that SKAP's binding to microtubules *reduces* friction at the kinetochore-microtubule interface and increases attachment stability under force. Congrats to postdoc Miquel @RosasSalvans and all authors! With @Caleb_J_Rux and Moumita Das.
https://t.co/PAm2jdBd4Y

[Sophie Dumont @DumontLab]

Nominate a colleague or yourself for the Motility and Cytoskeleton Early Career Award at the 2025 Biophysical Society Meeting! To do so fill out this form and email Radhika Subramanian and I your CVs by Dec 1 2024: https://t.co/cQ8rAnaN46

[Sophie Dumont @DumontLab]

Christina was a postdoc with Alex Dunn @Dunn_Lab. And wrote a book with Rob Phillips, The Restless Cell: Continuum Theories of Living Matter. Wow ...

[Sophie Dumont @DumontLab]

Congrats to Christina Hueschen @clhueschen, the first student from our lab to start their own lab! Her lab is in UCSD's Cell & Dev Bio Dept, studying the physical biology of parasites. Can't wait to see what science they do. Check it out! https://t.co/K37X52zu0O

[Sophie Dumont @DumontLab]

@MullinsLab @JTenthorey @UCSF @UCSFMedicine @UCSFcmp Congrats Jeannette!!!

[Sophie Dumont @DumontLab]

With this work we are sad to say goodbye to postdoc Miquel @RosasSalvans who is returning to Barcelona. We will miss Miquel's intellect, generous spirit, and all the fun times doing science together. Best of luck!

[Sophie Dumont @DumontLab]

Excited to share a preprint! We find that SKAP's binding to microtubules *reduces* friction at the kinetochore-microtubule interface and increases attachment stability under force. Congrats to postdoc Miquel @RosasSalvans and all authors! With @Caleb_J_Rux and Moumita Das.
https://t.co/SPKsDSFixM

[Sophie Dumont @DumontLab]

@ScienceyRosalie @RobertoZoncu @MarquseeLab @MullinsLab @MartinUCSF @TheHurleyLab @DJuliusSF @JTenthorey @dsboothacosta Congratulations to you both and have fun!!! 🤩

[Sophie Dumont @DumontLab]

Nominate a colleague or yourself to speak at the Motility & Cytoskeleton Subgroup at the 2025 Biophysical Society Meeting! Radhika Subramanian and I are organizing the subgroup and looking for nominations by July 8th: https://t.co/Ld4JIdspTX.

[Sophie Dumont @DumontLab]

Excited to share our work @JCellBiol! We find that torques within and outside the spindle oppose each other to limit spindle twist during anaphase. Congrats to @LilaNeahring who led the work! Thanks to Nathan Cho, @Caleb_J_Rux, @Yildiz_Lab, Upadhyayula and Subramanian Labs. https://t.co/oKMEl4juuK

[Sophie Dumont @DumontLab]

Excited to share our work @JCellBiol! We find that chromosome size-dependent spindle forces impair mammalian mitotic error correction of long chromosomes. Congrats to graduate student
@megan_chong who led this work! With Miquel
@RosasSalvans @VannaTran5
https://t.co/mSBj0Rs25G

[Sophie Dumont @DumontLab]

Excited to share our work out in @PLOSONE with @goga_lab showing that expressing an oncogene protects spindle poles from fracturing in mechanically confined environments. Congrats to first authors @RenaldoSutanto and @LilaNeahring and all authors! https://t.co/87eNGuUJsk

[Sophie Dumont @DumontLab]

@MEmilieTerret @alexpersat @LennonLab @NordenLab @DMVlab @Mech_Morph_Lab @SchnorrerL @AnneStraube @maitrejl @Franze_Lab @ManuelTHERY @MincLab @RongLabOfficial @WickstromLab @StefanDiezLab @LecuitThomas @gomes @RouxLab Thank you all for organizing, it was a wonderful conference!

[Sophie Dumont @DumontLab]

@JonathanAKuhn Congrats, Jon!!

[Sophie Dumont @DumontLab]

Congratulations to graduate student @megan_chong from our lab who received a UCSF Dean’s Award for Excellence in Mentoring! Megan is an inspiring mentor to many in our lab and out. And congrats to all other awardees! @UCSFGradDiv