Introducing ALFA-K for mapping karyotype fitness landscapes. We uncovered massive epistasis in karyotype evolution & estimated fitness of 272k karyotypes. Huge congrats to @Richard_J_Beck for crossing the finish line!
https://t.co/Zf3K7803Rr #cancerevo#mathonco#MoffittResearch
Live from #AACR25: Alexander Anderson, PhD, (@ara_anderson) leads the Adaptive Therapy from Board to Bench to Bedside and Back Again symposium. He shares how evolution-inspired treatment strategies like adaptive therapy can optimize drug use, delay resistance and improve outcomes across cancer types. #MoffittAACR25
🎉Thrilled to share that our paper is featured on the cover of CancerResearch: https://t.co/MgHWJWZZ23…Kudos to the entire team for this achievement, and a special shoutout to
@zuzannows
for the stunning cover design. Thanks to
@theNCI@mathonco@MoffittResearch
for the support
Excited to see this out! Huge credit to @Zuzannows and Frederika for leading the way. Our S3MB model recapitulates GBM growth and karyotype evolution post-surgery, revealing how resource access shapes tumor ploidy. Grateful to have been part of this with such a fantastic team!
Excited to share our software CLONEID at the #ITCR2024. CLONEID collects and maps genotypic and phenotypic data, across space & time. Use cases demonstrated by @thomasaveith and @Richard_J_Beck . Thanks to the #NCIITCR@theNCI for funding the work!
Today at #ITCR2024 we looked at CLONEID’s role in collecting genotypic and phenotypic data. Use case demo was a long term evolution experiment led by @VuralTagal with Jackson Cole
@EinsteinCross presenting her work at @NCI_CSSI #NCIITCR this morning.
This is my first time here for our new U24 with @FertigLab, and I couldn't me more thrilled with this amazing cancer informatics community! @IUImpact@mathonco@theNCI
Compelling talk from @benjraphael at the #ITCR2024 on quantification of spatial heterogeneity. Looking forward to using CalicoST to inform our mathematical models of chromosome mis segregations!
Excited to announce that registration for the 12th
@mathonco workshop on Treatment Toxicity is now open. Held onsite @MoffittNews Nov 3-Nov 8 #MoffittIMO more details: https://t.co/0cu3lbaXxm. Deluxe travel awards are available on a competitive basis, apply by 09/30!
It will be a great pleasure to attend and present at the 1st Polyploid Giant Cancer Cell Conference at the MD Anderson Cancer Center in Houston this week. @MDAndersonNews#Houston#Polyploidy#Cancer
Todays @mathonco research in progress is from @EinsteinCross lab member Richard Beck presenting, Modelling the Evolutionary Landscape of Aneuploidy @MoffittNews
If you are a High School student aged 16 or older and interested in learning how you can apply mathematics to cancer then consider applying to the @mathoncoblog fully funded High School Internship summer program @MoffittNews: https://t.co/PqiiccfBbp
A great study on the relationship between cancer cells, stroma and multifactorial drug resistance was presented by @AndriyMarusyk from Moffitt Cancer Center. @MoffittNews#AACRevol23#AACR
Noemi Andor (@EinsteinCross) has been presenting the last seminar so the headliner of the 2023 AACR Special Conference "Translating Cancer Evolution and Data Science: The Next Frontier" and informs the audience on ALFA-K. #AACR#AACREvol23#CancerEvolution#Aeneuploidy
.@val_boeva is talking next about "Unraveling potential genetic drivers of intratumor transcriptional heterogeneity and phenotypic plasticity in malignant cells" #AACRevol23