Regulatory Scientist/Research @23andMe;
Alum: @DukeSci_Soc. Sci Policy, Bioethics + human-centered approaches to genomics, research + tech. Views are my own
In a new collaborative study publish in @ScienceMagazine today, researchers at 23andMe and @DanaFarber used data from more than 3.3 million 23andMe consenting research participants to characterize a rare inherited EGFR variant that significantly elevates lung cancer risk, while also exploring its relationship to smoking, polygenic risk, ancestry and geography.
We found that the EGFR T790M genetic variant is carried by about 1 in 15,000 people in the United States, and is associated with a 25-fold increased risk of lung cancer. Among people who never smoked, carriers had a 60 fold higher odds of developing lung cancer than non-carriers.
Illustration credit: @oliveruberti
Learn more about the study and work here: https://t.co/CKYVhPBjeC
What can we learn about a single rare variant?
Published today in Science: the @23andMeResearch Institute and Dana-Farber studied the EGFR T790M in 11M 23andMe research participants. The variant has OR = 25.2 for lung cancer, rising to 61.7 in never-smokers(!). 🧵
Delighted to share our latest research from the @23andMeResearch Team, just published in @Nature
! We looked at data from >27,000 participants to uncover how human genetics influences weight loss efficacy and side effects of GLP-1 medications like semaglutide. A thread 🧵👇
Published in @Nature today, new research from the 23andMe Research Institute identifies genetic variants that may help explain why GLP-1 medications work differently based on genetics.
Read the announcement: https://t.co/xy0IuwnoEq
#GLP1#Genetics#PrecisionMedicine#Research
In our efforts to continue advancing research, we have recently expanded the ability to study the microbiome of 23andMe consented research participants. Learn more about this update and our previous microbiome study in our blog. https://t.co/ws7QYmceCG
Curious about 23andMe’s new Postdoc program?
Join our webinar Thurs Aug 18, 10am PT
Scientists from our Research and Therapeutics teams will talk about how research works at 23andMe and answer your questions about our #postdocjobs program.
Register now: https://t.co/sSmQI4UHmf
Always a pleasure to talk w/@arishapiro on @NPR especially w/@HankGreelyLSJU … with whom I nearly always agree. Except on the issue of direct access to health and genetic information about ourselves. #DTC#Genetics#ELSI
Join my team! Our favorite 23andMe core value: "Behind every data point is a human being." @23andMeResearch
Check out this job at 23andMe: Regulatory Scientist, Research Ethics https://t.co/1BHLFoQVwq
California’s new Genetic Information Privacy Act seeks to protect consumers’ genetic data privacy. 23andMe worked with the Coalition for Genetic Data Protection to support this law and continue delivering on our promises of transparency and choice. https://t.co/aSI3UGzUeD
@PatrickRothfuss Hi there! Could you please release the third book? I’m not sure I can wait much longer. I need to know how Kvothe is doing. I worry about him often
Excited to present our work on studying rare diseases using gwas on self-reported data today Oct 19 at #ASHG21 from 4-4:15 pm ET. Link to session https://t.co/Pad81sHtFF
Join us this Thursday for a free webinar, Ethics of Engaging International Populations in Research
Sept 9 from noon - 1:30pm PST
Featuring 23andMe's Regulatory Scientist Emily Bullis and collaborator Dr. Brenna Henn @HennLab of UC Davis
Register here: https://t.co/3MmGo4h7CI
23andMe is hosting a free webinar on COVID-19 research efforts
Thursday, July 22 from 9 - 10:30am PST
Featuring our Sr. Epidemiologist Janie Shelton, PhD and collaborator Andrea Ganna, PhD @andganna of the Host Genetics Initiative @covid19_hgi
https://t.co/m9y2KfV9LW