Francesca Lorenzin

[Francesca Demichelis @FrancescaBZNY]

Favorite study!

Germline-somatic tandems dictate cancer subtypes, provide clinical insights, and fuel molecularly informed studies.

Kudos: Blerta Stringa,
@Paola_Gasperini, Alessandro Alaimo, and
@LunardiLabCIBIO (co-last a!)
@NimaSharifiMD
https://t.co/cIHAS4PWFC
@UniTrento

[Thomas Cantore @cantore_thomas]

❗️Excited to share my PhD work in Genome Biology: PRODE recovers essential and context-essential genes through neighborhood-informed scores.

What is PRODE, and how does it help?👇

[Journal of Clinical Investigation @jclinicalinvest]

How can we make PARP inhibitors more effective in castration-resistant prostate cancer?

@FrancescaBZNY et al. identify the DNA repair gene LIG1 as a sensitizer to PARP inhibitors in multiple tumor models: https://t.co/6sQHKgmCOJ

@FraLo05 @GiuliaFracassi_ @CIBIO_UniTrento @AIRC_it @PCF_Science @ERC_Research

[Wolf Lab for Tumor Biochemistry @_WolfLab]

Our latest paper describing a role for SCAF1 in promoting RNAPII elongation is online at Nucleic Acids Research @NAR_Open! Check it out here: https://t.co/zmECC5yxRS. Big thanks to collaborators @erhard_lab, @MYCGyvers and AG Schlosser!

[Francesca Demichelis @FrancescaBZNY]

Proud of our LIG1 loss/PARP inhibition #SL study in @jclinicalinvest

by @GiuliaFracassi_ an @AIRC_it fellowship awardee
and @FraLo05 a @PCF_Science YIA

Collaborators: @quimmateo @FdAdF66

Relevant to #prostatecancer and beyond. Download it!
https://t.co/j3n4UdVdxl

[Giulia Fracassi @GiuliaFracassi_]

🚨 New Preprint Alert! 🚨

I’m thrilled to share our latest study now online on JCI: 
CRISPR/Cas9 screens identify LIG1 as a sensitizer of PARP inhibitors in castration-resistant prostate cancer.

🔬 Check out the preprint here: https://t.co/Svr0nSY1CF

Huge thanks to @FrancescaBZNY, @FraLo05, all Demichelis’ lab members and facilities staff at @UniTrento @CIBIO_UniTrento, and key collaborators @quimmateo, @FdAdF66 and Helmut Klocker.

Special thanks to Fondazione Trentina per la Ricerca sui Tumori, @AIRC_it fellowship, @ERC_Research, @PCF_Science, and MIUR.

#ProstateCancer #CRPC #LIG1 #PARPi #Biomarker #SyntheticLethality #PrecisionMedicine

[EVIta- Italian Society for Extracellular Vesicles @EVItaSociety]

🔥Post-doc position open🔥 at the Demichelis laboratory @UniTrento
⏳ application by August 31st!
👉 more info https://t.co/znO0SGf5Di
#oncosome #prostatecancer #evitians @CaterinaNardel1 @FrancescaBZNY

[Yari Ciani @YariCiani]

I had the honor of writing a preview of the article published by @ICasanovaSalas et al. in the latest issue of @Cancer_Cell . https://t.co/dF910tLYMj

[Fondazione Pezcoller @pezcoller]

The recipient of @embojournal Molecular Medicine poster prize is:
Fracassi Giulia @GiuliaFracassi_

@CIBIO_UniTrento @UniTrento

[Cusanelli Lab @LabCusanelli]

Happy to share our recent publication on #TERRA participating in #telomerase regulation at human #telomeres. https://t.co/ldnDgUXA2a. Great work from @Bettinnicole_ and coworkers in collaboration with Chartrand lab @UMontreal. @ScienceAdvances @AIRC_it @CIBIO_UniTrento @UniTrento

[Wolf Lab for Tumor Biochemistry @_WolfLab]

We are recruiting: ERC- and DFG-funded PhD positions in Tumor Biology (Kiel, Germany).
We look forward to your application!

[Enrico Domenici @EnriDomenici]

Interested in the interplay between human #genetics and the #microbiome ? Nice opportunity for a #PhD position in my lab at @CIBIO_UniTrento in collaboration with @asnicar and @nsegata at @cibiocm Check for scholarship 1C here: https://t.co/rz8ht0kQGN deadline 17th June

[CIBIO - UniTrento @CIBIO_UniTrento]

CIBIO is hosting Titia De Lange from @RockefellerUniv winner of the 2024 @pezcoller @aacr Award for the Pezcoller Lecture:
Telomeres and #Cancer: Tumor Suppression and Genome Instability

🗓️ May 10th, 2.30 p.m.
🏦 Sala Stringa, FBK
ℹ️ https://t.co/gi4GaXrirm
#CIBIO

[CIBIO - UniTrento @CIBIO_UniTrento]

The department has launched a call to fill a tenure-track assistant professor position in molecular biology (RTT, BIO/11). Send your applications in!

📅 May 16th, 12.00
➡️ Apply here: https://t.co/JEs4d1FYW6

#ScienceJobs #research

[Abdallah Gaballa @AbdallahHatem4]

Have you ever wondered if transcription elongation could influence tumor immune evasion?
Happy to share results from my PhD work @MYCGyvers @Uni_WUE published @NatureComms.
Check it out https://t.co/yfiWgAgYvP
#MYC #PAF1c #PDAC #immune_evasion #PDAC 1/2

[Luca Fava @LucaFava14]

A couple of years ago Andi @villunger and I suspected that extra centrosomes kill blood cells via Caspase-2. Problem was: ko of candidate substrates had no phenotype. Now @dario_rizz and @VincenzaVigo figured out why https://t.co/hvEhbQbpf7

[The EMBO Journal @embojournal]

Surprising mechanism revealed by androgen-independent PSA spikes in chronic prostate inflammation:
EV-delivered TRPM8 mRNA promotes TLR3 & NF-kB signaling, and antitumorigenic sterile inflammation
@AlessandroAlai7 @LunardiLabCIBIO et al @CIBIO_UniTrento
https://t.co/htHHD29u7O

[PCF Science @PCF_Science]

ANNOUNCEMENT: RFA for 2024 @PCFnews Young Investigator Award Applications, to support innovative & highly promising early career #ProstateCancer researchers.

DEADLINE: 4/15/24

Application Portal opens 1/29/24
https://t.co/dlTP0futsZ

View the RFA here: https://t.co/bNnRQrLIJQ

[Gian Marco Franceschini @GMFranceschini]

I am beyond excited to see our work out in @CD_AACR . We established a targeted sequencing assay to non-invasively monitor treatment resistance in advanced prostate cancer. Want to know more? Let’s take a short walk 👣

https://t.co/zKlDZe0Dsh

[Misha Beltran @mishabeltran]

Noninvasive detection of NEPC by targeted cfDNA methylation @CD_AACR co-led by @FrancescaBZNY and her lab @UniTrento. Congrats to first author @GMFranceschini and thank you to many amazing collaborators @PCF_Science @DanaFarber_GU #NEMO

https://t.co/rToG0QfXB1