Michael Keogh

Back traveling again (!!!) ...

[EpiCypher, Inc. @epicypher]

Now streaming ▶️

Missed Michael-Christopher Keogh’s talk in the 2026 Fragile Nucleosome series? The replay is live on YouTube.

🔗 Watch now: https://t.co/yR4fu87XhK

[Michael Keogh @GCloner]

Some forms of heterologous competition for the nucleosome acidic patch are tolerated by cells, but an 'arginine anchor' causes profound problems. A collaboration between labs of Jim Kadonaga, @valendraica, @GCloner, @EpiCypher and @ujanichakrabort in @jesstylerlab.

[Jean-Paul Armache @valendraica]

A wonderful collaboration between @jesstylerlab, @epicypher, @gcloner, James Kadonaga and our lab at PSU. In this article, we provide the significance of the nucleosome acidic patch

https://t.co/gr6kW5lF7w

[Michael Keogh @GCloner]

@epicypher Thanks to all the speakers for great talks / science !!

[EpiCypher, Inc. @epicypher]

Our #Epi2025 Trainee Session honoring the legacy of C. David Allis was an incredible success last night! Huge thank you to our selected trainees for sharing their outstanding research, and to our session chairs for organizing such a thoughtful introduction honoring Dave.

[Dr. Nicolas L. Young @NicolasLYoung]

Today, we introduce a nomenclature that can express discrete PTMs, proteoforms, nucleoforms, or situations where defined PTMs exist in an uncertain context and can describe how proteoforms are configured in functionally distinct complexes across biology. https://t.co/WrMYTXamIe

[Michael Keogh @GCloner]

@NicolasLYoung @DrBrianStrahl @NLKProteomics @MusselmanLab @MuirLab @Beatfierz @jerryleeworkman @CWolberger @KarenGlassLab @lab_hat .. Great to have a new way to be VERY clear what we mean (and our degree of confidence in saying it) ... Thx for bringing it all together Nick (!!)

[Michael Keogh @GCloner]

22x Chromatin Readers dissected for their histone nucleosome binding by biochemical, proteomic and genomic approaches - major biological insight revealed [!] ..[https://t.co/6mokpnM8f6] @epicypher @MusselmanLab @NLKProteomics

[Michael Keogh @GCloner]

@biorxiv_genomic If you want a synthesis of ALL that we've learned at EpiCypher in how to approach, perform and analyze a CUT&RUN experiment ..

[Michael Keogh @GCloner]

Chania Crete for Aegean Conference ! Going to guess the local Mouse population is minuscule and edgy ..

[Michael Keogh @GCloner]

Hong Kong airport walking to gate 447 / bugger …

[EpiCypher, Inc. @epicypher]

To begin to undercover immune cell diversity, we partnered with @ImmGen_ to use our low-input automated CUT&RUN platform to process >1,100 samples and generate chromatin profiles from 94 cell types, including ultra-rare cell populations.

Explore here! https://t.co/I3g3JQ8vtR

[Michael Keogh @GCloner]

Welcome to Busan Korea .. the location for KSBMB .. and apparently that breeding colony you’re having problems with (presumably the kimchee is key) …

[Michael Keogh @GCloner]

They have a beautiful campus at Seoul National University - as I found out when I gave the wrong address to Taxi driver - a very pleasant 30min walk ensued to visit Sung Hee Baek ! #asiatravels

[Michael Keogh @GCloner]

Behold : the coin-on-side stability of the Shanghai to Beijing bullet train [and at 347kph / 215mph] !

[Michael Keogh @GCloner]

@frcbs_Tsinghua Huge thanks to my host Haitao Li !! Great facilities, audience and dinner companions !!

[Michael Keogh @GCloner]

@theNASciences @harvardmed Congratulations Danesh !!!

[Michael Keogh @GCloner]

@epicypher @NLKProteomics Thanks so much to Neil for visiting : Nucleosomics updates always fun to discuss !! @epicypher #nucleosome

[EpiCypher, Inc. @epicypher]

Another great day at EpiCypher! We hosted @NLKProteomics - who described how mass spectrometry methods are transforming the study of nucleosome modifications and the histone code.

Great to see you, Neil!

[Michael Keogh @GCloner]

@DrawImpacts @MolecularCell @GayathriArunaM @JswLab @guna_alina Oh that is good !!!!

[Michael Keogh @GCloner]

@KristjanGretars @LuLaboratory @KJArmache @epicypher @Xagbomson Always fun to work with smart and engaged collaborators !! Our third study on DNMT3A + Nucleosomes and getting an ever deeper understanding of its biology.