Gareth Moore

Postdoc @LabTrivedi🫘 PhD @TheAsheLab and @BaldockLab at the University of Manchester🪰

[Trivedi Lab @LabTrivedi]

We are excited to share the latest contribution from the lab! We found that cells in gastruloids communicate to each other in order to control the timing of gastruloid symmetry breaking.

[Gareth Moore @Gareth_R_Moore]

Glad to share the second half of my work on Tsg focusing on the second half of the protein! Read below for modelling, mutations, embryos and even a bit of evo-devo! 🪰

[The Ashe lab @TheAsheLab]

Excited to share our latest findings on the extracellular regulation of BMP signalling by Twisted gastrulation! We identify how Tsg binds the Chordin family of BMP antagonists, leading us to propose an avidity-driven mechanism of BMP signalling control. https://t.co/tizEHfV7zq

[Trivedi Lab @LabTrivedi]

Congratulations to Kerim Anlaş, @nicola_gritti & @LabTrivedi @embl @the_prbb for the work on early autonomous patterning of the anteroposterior axis in gastruloids @Dev_journal.

https://t.co/EBlkoms9mv

[Gareth Moore @Gareth_R_Moore]

@TheAsheLab @Nabarundevbio Happy Diwali 🪔 sad to have missed @Nabarundevbio ’s amazing food!

[Nature Communications @NatureComms]

Authors from @TheAsheLab, @BaldockLab including @t_malinauskas and @Gareth_R_Moore report structures of TWSG1 in complex with a BMP ligand and show how TWSG1 inhibits signaling.

https://t.co/ZWgPPkWBKd

[Gareth Moore @Gareth_R_Moore]

@drjrdavis @t_malinauskas Thanks JR!

[Gareth Moore @Gareth_R_Moore]

Absolutely delighted to share this work on the conserved interaction between Twisted gastrulation and BMPs! Congratulations to my co-first authors Tomas @t_malinauskas and Amalie, and the entire team! Take a look here: https://t.co/IHcgWGAtUn

[Gareth Moore @Gareth_R_Moore]

@declan_c9 @CM_Grant @Markashe @SimonHu02406809 @astacus @MCF_UoM Congrats Declan, fantastic work 🥳

[Tomas Malinauskas @t_malinauskas]

The evolution of multicellular organisms led to the development of body structures and functions. During embryogenesis, establishing three body axes–anterior-posterior (head-to-tail), dorsal-ventral (back-to-belly), and left-right–is essential for the organism's development. 1/n

[The Ashe lab @TheAsheLab]

It's that time of year again - we are collecting donations of festive food and gifts for @EmmelinesNew to help support local families this Christmas 🎁

The collection will run throughout November - please get in touch if you wish to get involved! 🎅
@MCF_UoM @FBMH_UoM

[The Ashe lab @TheAsheLab]

Please RT - we are looking for a postdoc to investigate how signalling filopodia collect and transduce the #BMP signal in #Drosophila ovarian germline stem cells, collaborating with @ShukryHabib_Lab in beautiful Lausanne! 🪰🏔️

Full details in the ad:
https://t.co/BRODRgm6yS

[The Ashe lab @TheAsheLab]

Lab lunch today saying hello to our new post-doc Amanda and saying gooodbye masters student Harry- well done on your hard work! 😊🪰🔬

[Barcelona Collaboratorium @BCNCollab]

🙌Friday was the last day of the Computational Modelling of Multicellular Systems course. Below is a picture of all the participants and some of our teachers.

It was great to have you here!

#EMBOMulticellModelling

@EMBO @EMBLBarcelona @EMBLEvents

[Gareth Moore @Gareth_R_Moore]

Grateful to be doing my PhD with such a great team of scientists (and flies 🪰)!

[the Node @the_Node]

Next in our 'Lab meeting' series is @TheAsheLab @OfficialUoM, UK!

The lab investigates how cell signalling and gene expression dynamics control developmental patterning, using #Drosophila embryo and ovarian germline stem cells as models.

Meet the lab: https://t.co/2pf1wliKeX

[baldocklab @baldocklab]

We’re really excited to share our latest paper published in NSMB on the structure of #fibrillin microfibrils by #CryoEM @wtccmr @OfficialUoM
https://t.co/gGuH3OmAbR

[The Ashe lab @TheAsheLab]

Excited to share our latest research out today in @CellReports looking at transcriptional bursting of X chromosome genes in the Drosophila embryo. 🧬🔬

https://t.co/3cQRXlbyq1

[Gareth Moore @Gareth_R_Moore]

Really enjoyed hearing about all the cool science going on around me in @MCF_UoM and pleased to have won a poster prize!

[The Ashe lab @TheAsheLab]

Brilliant to hear about the breadth of research going on here @MCF_UoM at the MCF away day, including our new neighbour @hungrytissue as well as valuable discussions about EDI 💡 Congratulations also to @Gareth_R_Moore for winning a poster prize, a great start to the year!🪰🧬🧫

[The Ashe lab @TheAsheLab]

We are hiring! There are TWO exciting new postdoc positions in the lab building upon our previous work on #BMP signaling both in the #Drosophila embryo and germline stem cells. Please RT and share, full details in the thread 🪰🧬🔬🥼

[The Ashe lab @TheAsheLab]

Great to see this work from @laurenfb267 @jenniferc_love and @y_shapovalova as part of our collaboration with @MagnusRattray published! RNA-seq, mathematical modelling and imaging ⬇️🧬🧮🔬