Our June issue is live! ๐
https://t.co/cDN8qlkTyS
On the cover, from @GuptaLab1 and artist Hanna Wang, a native mass spectrometry platform captures membrane proteinโlipid organization directly from tunable lipid membranes.
Paper here: https://t.co/iL9T8sy9kl
If @ #BPS2025 , check out the talk by @CBcellbiologist today in the "Protein Lipid Interactions: Structure and Dynamics" Session @ 12PM. She will present our recently developed platform to capture membrane proteins in their native nanodomains & some exciting applications of it
Very excited to see this work coming out. Combining membrane-active polymers with #proteomics we present the most optimal conditions to extract>2000 individual endogenous membrane proteins into nativenanodiscs
@YaleCellBio@YaleWestCampus@YaleMed
Work from @GuptaLab1 presents a high-throughput platform for extracting membrane proteins into native nanodiscs that retains the local membrane context, accompanied by a database of optimal extraction conditions for 2000+ mammalian membrane proteins.
https://t.co/HPEme6JZ0J
All Data publicly available via https://t.co/3Q8LbABfHc & https://t.co/j4TLkmzAkg Searchable through Uniprot names. We hope this will enable #membraneprotein researchers to extract & study their favorite proteins, at endogenous expression levels, directly from native environment
If you are @ #BPS#Membrane#Biophysics meeting @Tahoe, check out Caroline's talk today. She describes our new & exciting platform to capture >2000 unique #membraneproteins in their native nanodomains with high efficiency and nanoscale spatial resolution
If @ #BPS2024, check out all our exciting works describing new technologies to study molecular organization of #membraneproteins and #lipids directly from the #membrane and its applications in understanding various membrane-associated signaling events
Our article on in vivo force sensors appeared in Science Advances. Thank Yuan Ren, Julien Berro @BerroLab, and Jie Yang! Force redistribution in clathrin-mediated endocytosis revealed by coiled-coil force sensors | Science Advances https://t.co/4f8bYFUQKw
Extremely honored to be recognized as an Emerging Investigator by the American Society for Mass Spectrometry @asmsnews. Credit goes to my amazing lab members for their hard work. Special thanks to my past mentors & present colleagues at @YaleWestCampus@YaleCellBio@YaleMed