Sir Henry @wellcometrust postdoc fellow with @Tanaxolotl & @briscoejames labs | @ImpVienna & @TheCrick | PhD @SCICambridge | never too many cacti or hamsters |
So happy to finally share for the first time how to obtain neural organoids from human naïve pluripotent stem cells! Thanks to the huge effort of @CeciliaLaterza_@cesare_elisa@H_T_Stuart and all the contributors 🥳
I am beyond excited and happy to share that our work is finally out in @Dev_Cell as of today🥹🥳
“Mouse neural tube organoids self-organize floorplate through BMP-mediated cluster competition”
https://t.co/PzM5jT433i
I am very excited to share our latest manuscript on the axolotl nervous system. We established the use of adeno-associated viruses (AAVs) to perform circuit tracing in the axolotl brain and retina: https://t.co/OTlsURssHX with @Tanaxolotl@IMPVienna
📢 It is with joy and humbleness that I share our first contribution to Huntington Disease(HD) research, out in @NatureComms. We identified genes with therapeutic potential against HD using pluripotent cells. 1/11
https://t.co/ESNPyOHNWN
#HuntingtonsDisease#stemcells
Have you ever wondered who organizes the organizer? Excited to share our latest discoveries about how a global application of retinoic acid (RA) can induce polarized neural tube organoids (NTOs).
For more details, check out our pre-print below:
https://t.co/5aOSStVr6k
1/6
I find so eternally alluring this developmental biology question of ‘who organises the organisers?’. Check out this beautiful and relevant new preprint of work spearheaded by @teresakatharin1, @Hstuart21, Elena Gromberg and others. Congratulations! https://t.co/knGnKzavdM
New from Teresa Krammer, @Hstuart21 & co
Organisers organise in organoids. But how?
BMP signaling & physical sorting is responsible for self-organisation of FoxA2 expressing floorplate in neural tube organoids derived clonally from ES cells in vitro
https://t.co/l7gl0u4w7t
We are really excited our work is finally out @CellStemCell!
Have a read if you want to know more about the supportive role of ECM on human naive pluripotency.
Congrats to @cesare_elisa@UrciuoloLab @Hstuart21 for the amazing work 👏
Really excited to share our paper on @NatureGenet about the impact of mitochondrial metabolism on nuclear DNA methylation. Thanks to @ERC_Research ,@ArmeniseHarvard, @Telethonitalia, @UniPadova for the amazing support.
https://t.co/nk2nZocciN