Our new paper is out ๐
We developed a new (and cool) single-molecule assay that allows us to follow in real-time the binding and dissociation events of an individual, unlabeled TF on the DNA!! Check the preprint to learn more
- How to characterize the full distribution of binding and dissociation times of unlabeled transcriptions factors?
- How do DNA sequence and methylation affect these kinetics?
Our new work, leaded by @Hadeel_Khamis8 , is out
https://t.co/xUE6Es9L2F
Here is a short thread:
How do ATP molecules rapidly reach their catalytic sites in the ultrafast helicase RecBCD?
Our new publication, in collaboration with Arnon Hennโs and @KleifeldO, is now out in @NatureComms:
โAuxiliary ATP binding sites support DNA unwinding by RecBCDโ 1/n
https://t.co/hxGV7Ii8Lh
Indeed it is hard to say goodbye to such a great friend and scientist as @nucleosomezky, but I am sure you will succeed and prosper in your new journey. Your impact will forever hunt me ๐. Good luck ๐
Hard to believe we're parting today with Dr. Sergei Rudnizky (@nucleosomezky), who is leaving to work with @taekjip and Carl Wu, with an @EMBO fellowship. Congratulations Sergei, it's hard to overstate what a privilege it was to have you in the lab!
@nucleosomezky@akaplanz@nucleosomezky you are the best and certainly the most brilliant colleague a person can ask for. Thank you for pushing me to my limits and for making me a better scientist, and may our paths cross again and again๐๐งฌ
It was a privilege to work in such a warm and family-like lab, with top-notch science ๐ฌ ๐งฌ. I will always have all the memories and moments to treasure. Thank you @akaplanz for being the best Supervisor I could ever ask for, and for all the lab members that became my family.
Today we say goodbye to Dr. Hadeel Khamis (@Hadeel_Khamis8 ), who is leaving behind many good memories and excellent science. It was great having you around. Good luck with your new adventures!.
Azrieli Fellowships - An excellent opportunity for postdoctoral candidates from Europe and Canada interested in working in Israel
https://t.co/OTkQsFAOtT
Come work with us using single-molecule methods to study chromatin dynamics and transcription!
https://t.co/em4X1TXdkY
If you finished your PhD in the EU, UK or Canada, and you are interested in studying chromatin dynamics and transcription with advanced single-molecule biophysical tools, check out this opportunity from the Azrieli foundation (DEADLINE NOV 2):
https://t.co/HHlnBLuYep
- How to characterize the full distribution of binding and dissociation times of unlabeled transcriptions factors?
- How do DNA sequence and methylation affect these kinetics?
Our new work, leaded by @Hadeel_Khamis8 , is out
https://t.co/xUE6Es9L2F
Here is a short thread:
If you are interested in ML/AI, enhancers and chromatin & epigenetics and looking to do a PhD in UK get in contact. funding (home fees + stipend) available. DM me. Pls RT. Deadline very soon.
Officially published ๐ check our paper, and see our cool method to follow in real-time the kinetics of a single TF on a single molecule of DNA. Thanks to @akaplanz,@nucleosomezky, and @LabPMelamed for your amazing collaboration
Single molecule characterization of the binding kinetics of a transcription factor and its modulation by DNA sequence and methylation https://t.co/p1DkKuqDN1 Congratulations @Hadeel_Khamis8!
The seminal discoveries by this yearโs #NobelPrize laureates in physiology or medicine have explained how heat, cold and touch can initiate signals in our nervous system. The identified ion channels are important for many physiological processes and disease conditions.