Philipp Heilen

[Christian Schroeter, @Schroeterfisch]

Nice to have our latest paper on the regulation of AVE differentiation featured as an Editor‘s Highlight https://t.co/UJkNpoVm4Z @NatureComms @mpimoph @IMPRS_LM

[MPI Dortmund @mpimoph]

We are proud of @oleg_sitsel former @Intein lab postdoc
who is now Assistant Professor and head of the Marine Structural Biology Unit @OISTedu . We wish him much success and all the best on beautiful #okinawa #cryoEM

[FEBS Letters @FEBS_Letters]

🎨 Featured on the cover of our latest issue:

#CryoEM structure of the #Slo1 potassium channel with the auxiliary γ1 subunit

Read the article here: https://t.co/KIqL04Js1c

@TobiasRaisch @Intein @mpimoph

[Philipp Heilen @HeilenPhilipp]

@DuccioConti @maikaboiero @WoutOosterheert @Intein One ring to rule them all! Brilliant work by awsome people. Congratulations

[Wout Oosterheert @WoutOosterheert]

Our latest work on #actin assembly is now online @ScienceMagazine!

We show how #formins bind and move with the growing barbed end of F-actin.

Awesome collab. between @Intein and Bieling labs @mpimoph, and big thanks to co-first author @maikaboiero

https://t.co/I6A17Jcz8a

[MPI Dortmund @mpimoph]

The @TobiasRaisch group together with @Intein has solved the #cryoEM structure of the Slo1 potassium channel and suggest a novel activation mechanism of voltage-gated ion channels!
Congrats to Tobi on his first last author paper!
https://t.co/gKVH6JCY6V

[alexander.belyy @alexanderbelyy1]

Looking for a PhD student to join my group studying bacterial virulence factors using cryo-EM, advanced biochemistry, and molecular biology.
Modern environment, amazing colleagues, and a lively city in the Top of the Netherlands!
Apply: https://t.co/DCIzFW9r7q

[Deniz Ugurlar @denizugurlar]

Hear from my colleagues about how we're witnessing the start of the next wave of innovation in cryo-ET. #TeamTomo @cenmag #cryoEM https://t.co/txVzmJkcdQ

[Oleg Sitsel @oleg_sitsel]

So proud that our Tc toxin release story with @Intein was featured on the cover of today's @NatureMicrobiol issue! 🎉
Check out this 💥explosive 💥tale here: https://t.co/kZS1vHro0p

[IMPRS for Living Matter @IMPRS_LM]

Cool! Well done @alexanderbelyy1 and @HeilenPhilipp!

[Philipp Heilen @HeilenPhilipp]

Well said! Check out the press release @mpimoph of our Makes Caterpillars Floppy 1 🐛 #toxin story from @intein lab. Special thanks to @alexanderbelyy1 for guiding me all the way, a true scientist and awesome mentor!

[alexander.belyy @alexanderbelyy1]

Are you ready to meet the #toxin with the most AWESOME name? Say hello🤗 to The Makes Caterpillars Floppy 1 toxin! It took us nearly a decade of work🔬 to find out what it looks like, but it was really worth it. Look at this 330 kDa giant beauty full of secrets! Thread 1/8.

[Oleg Sitsel @oleg_sitsel]

Our paper revealing how specialized #Yersinia cells 🦠release a deadly Tc toxin-containing cocktail ☣️ by blowing themselves up 🧨🤯 is finally out!
Read it in @naturemicrobiol: https://t.co/kZS1vHro0p
#toxin #pathogen #tomography #explosion #T10SS

[Nature Microbiology @NatureMicrobiol]

New study out now on sub-population T10SS-dependent release of toxins by 🦠 Yersinia entomophaga #toxin, #pathogen, #tomography, #explosion, #secretion, #T10SS @mpimoph @oleg_sitsel @Intein https://t.co/wDl6hQbLsL

[MPI Dortmund @mpimoph]

Read how a few soldier cells armed to the teeth confer virulence to an entire bacterial #Yersinia population by sacrificing themselves - find the corresponding paper in @naturemicrobiol @Intein @oleg_sitsel @Zhexin_Wang @pixelbaumarkt @maxplanckpress

https://t.co/JEX4aCKNc1

[Peter Njenga, Ph.D. @NjengaPAN]

Very excited to share our preprint on the multi-state kinetics of the syringe-like injection mechanism of Tc toxins. Great collaboration between the Raunser @Intein @mpimoph, Seidel @HHU_de, @enricabordignon @sciences_UNIGE and Dong @harvardmed labs.
https://t.co/lbaE6NVtGX
1/3

[MPI Dortmund @mpimoph]

The molecular structure of myosin filaments has remained elusive. In this week’s @Nature issue, two papers — one by Roger Craig and colleagues, the other by @Intein and co-workers use #cryoEM #cryoET to reveal the structure of these filaments in unprecedented detail

[bioRxiv Biophysics @biorxiv_biophys]

Cryo-EM structure of Slo1 with the auxiliary γ1 subunit suggests mechanism of depolarization-independent activation https://t.co/ZlWb6c16qG #biorxiv_biophys

[Membrane Protein PDB @MemProtPDB]

Cryo-EM structure of Slo1 with the auxiliary γ1 subunit suggests mechanism of depolarization-independent activation | bioRxiv

https://t.co/3BHt17opiR

#CryoEM #ionchannel #MembraneProteins

[nature @Nature]

Nature research paper: Structure of the native myosin filament in the relaxed cardiac sarcomere https://t.co/g1mgGm5MXm

[Raúl Padrón @raulpadron]

The @UMass Padron-Craig lab #Cryo-EM paper (Dutta et al.) back-to-back with Raunser lab #Cryo-ET (Tamborrini et al.): an example of complementarity and reproducibility of these #EM techniques.
Dutta et al https://t.co/oUeBWQO0IV
Tamborrini et al https://t.co/6BAwdtMkBt