shiqiong hu

Scientist enthusiastic about actomyosin cytoskeleton, advanced microscopy, and molecular and cell biology.

[Bechara Kachar @BecharaKachar]

5/5

This study https://t.co/ZlP3wzqYbc was made possible by a fantastic team: @amirrasoultav and @HuShiqiong @NIH and @sehamebrahim @UVA

[Bechara Kachar @BecharaKachar]

4/5

We propose an ESCRT-independent mechanism for intraluminal vesicle and multivesicular body (MVB) formation.

Via PND-driven vesicle generation, hemifusion, and internalization, hemifusomes act as hubs for building complex MVBs - no ESCRT machinery required.

[Bechara Kachar @BecharaKachar]

New organelle uncovered by in situ #cryoET: the #hemifusome, a stable, hemifused vesicle pair separated by an extended hemifusion diaphragm. This structure redefines what membrane fusion intermediates can do.

https://t.co/ZlP3wzqYbc

#CryoET #MembraneBiogenesis #Organelle

🧵1/5

[shiqiong hu @HuShiqiong]

Excited to share our new paper @NatureComms - Hemifusomes and interacting proteolipid nanodroplets mediate multi-vesicular body formation. Thank you all for a great collaboration @amirrasoultav @sehamebrahim @BecharaKachar
https://t.co/VKPSBIHQzO

[Seham Ebrahim @sehamebrahim]

Early for #MicroscopyMonday: #Hemifusomes- Newly discovered ESCRT-independent intermediates of intraluminal vesicle and multivesicular body formation!
In collaboration with @BecharaKachar Lab @NIH
@NatureComms: https://t.co/Wpqbjp7fAQ
#cryoET #trafficking #organelle #hemifusion

[Seham Ebrahim @sehamebrahim]

We are thrilled to share a truly exciting discovery by cryo electron tomography: the “hemifusome”- a new cellular organelle complex containing a hemifusion diaphragm! Tavakoli et al.
https://t.co/YPio7TscYJ
@amirrasoultav, @HuShiqiong and @Becharakachar
Tweetorial below (1/8)

[Uri Manor @manorlaboratory]

New work from Hari Shroff looks gorgeous
https://t.co/JJQA7vXLzy

[Nature Communications @NatureComms]

The @Hahn_Lab @HuShiqiong @tcelston45 @jcherronvfb and colleagues use iPALM microscopy to reveal the “hourglass” shape of the podosome actin core

https://t.co/XKiu1w9Q9z