Hybrid Automata Library is a Java library for hybrid agent-based reaction diffusion modeling both on & off lattice in 2 & 3D developed by the #AndersonLab
It’s been a long time coming but HAL is finally published in @PLOSCompBiol check out our software paper https://t.co/BdUzIUJJxd and our website https://t.co/5fHNBbJ0og for more details on how to get started with our quick prototyping agent based platform! #AndersonLab
Exciting News! Lenia-in-HAL! 🚨
We released Lenia in the Hybrid Automata Library (@HybridAutomata) and everyone can implement Lenia using this link
https://t.co/6c9JjmsyaA
Immune escape is a logical setting to implement an investigation into collective/group phenotypes (e.g. metaphenotypes, if you will)
Tumor-immune interactions are by a definition, a collective phenomenon by requiring the presence of two cell types interacting in close proximity: tumor and immune.
"Spatial interactions modulate tumor growth and immune infiltration"
Our latest preprint:
@S_Marzban in collab w/ @AmelioLab!
We apply methods from artificial life, @BertChakovsky's #Lenia, as a model of tumor-immune:
- spatial growth dynamics
- cell-cell competition &
- cell migration
Application to head & neck squamous cell carcinomas to elucidate the role of collagen on immune infiltration
https://t.co/Uzg9lhp9rn
Super chuffed to see @mathoncbro artwork generated with @HybridAutomata on the cover of @TrendsCellBio for our recent article with @markrt_ on how, Agent-based methods facilitate integrative science in cancer. https://t.co/DgxWGEyU07
Re-sharing this old blog post on combining @HybridAutomata with #EvoFreq:
https://t.co/wiTQfl968p
even though i wrote it, i still refer to it myself when building models 😅
This is so cool, our theoretical work led by @mathoncbro with @markrt_ using @HybridAutomata comes to similar conclusions but we use a buffer agent to modulate acidity and our model is of a more generic ductal tumour: https://t.co/rGHcyhL7zB
Please to announce our latest paper led by @research_junkie just out in @PNASNews on how, Homeostasis limits keratinocyte evolution. #AndersonLab Many years in the making with help from Eunjung Kim, Rafael Bravo, @mathoncbro@leedham_simon & Darryl Shibata https://t.co/QdexxWOR4L
I’m excited to share our recently published manuscript in PNAS on clonal dynamics in the homeostatic epidermis. This paper took a winding course and was the first project that was incorporated into my DPhil. 1/🧵
Check out the landing page for @CommsMedicine https://t.co/OQpTAVnFB7 highlighting @StroblMAR latest paper https://t.co/VdUkqgfNBL we see a gorgeous multi panel set of simulations using @HybridAutomata
Another neat example of modeling using @HybridAutomata , this time in SARS-CoV-2 applications:
https://t.co/hwuMXatdhB
nice work @gergely_rost & @S_Marzban et al 💯
Pleased to share a new collaboration with @cmaley on @EvolTherapy led by Daniel Thomas: In Silico Investigations of Multi-Drug Adaptive Therapy Protocols https://t.co/yPJ3B2Lf3r Another great application of @HybridAutomata!
My latest weekend project: implementing @BertChakovsky's Lenia project in @HybridAutomata.
It's an elegant and mathematically beautiful method to extend discrete cellular automata (e.g. Game of Life) to allow continuous states.
🧵 incoming thread of cool automata gifs:
Check out the landing page for @CommsMedicine https://t.co/OQpTAVnFB7 highlighting @StroblMAR latest paper https://t.co/VdUkqgfNBL we see a gorgeous multi panel set of simulations using @HybridAutomata
I had to get up very early to talk about our hybrid agent based - partial differential equation model for viral dynamics (https://t.co/hhM5lEOIZl) in the morning news of Hungarian national televison: https://t.co/HWae1FVVkx
Pleased to announce the release of #AndersonLab latest tool: GATTACA, for base pair resolution mutation tracking in agent-based models like @HybridAutomata. Developed by @research_junkie for our somatic evolution studies. Here’s a cool gif! https://t.co/lLZntrg5fY
Learned something new from @normonics' talk at #RWRI today -- Turing patterns can form in an *extremely simple* discrete cell automata:
Here's my code using Young's model (1984) created in @HybridAutomata):
https://t.co/eQqn0o61cM
(the C.A. rules are in the next tweet)