Chen Chen

DMPK Postdoc at Genentech | PhD @TPCB_NYC

[Daniel Heller @Dan_A_Heller]

Excited to report our newest work by Dana Goerzen et al on Machine Perception Liquid Biopsy (MPLB) of brain tumors from a blood test, which enables detection, identification, and biomarker discovery of tumors via @nanocarbons and machine learning!

[Daniel Heller @Dan_A_Heller]

Congratulations to @HydroChen2, @anamariepereaa, and colleagues who found that nanoparticles can take advantage of the lysosome to sequester drugs to control/prolong their release into the cell and increase anti-tumor efficacy! https://t.co/bZuKJ0K4UQ

[Chen Chen @HydroChen2]

Many small molecule drugs given IV to bile duct cannulated rats can still be recovered in the intestine. Our new study in JMedChem systematically establishes a framework to explain, predict, and chemically manipulate this direct intestinal excretion clearance route.

[ACS Publications Bio & Med Chem Content @ACSBioMed]

A new study in #JMedChem by Chen et al. reveals that direct intestinal excretion is a major, underappreciated drug clearance pathway. The work provides a simple logD/pKa decision tree to help chemists predict and design drug elimination routes. #DMPK

https://t.co/jB0GNxlkfG

[Gabriella Chua @BetterAtCloning]

When Force Met Fluorescence…👯‍♀️
Was grateful for the opportunity to write (and 🧑🏻‍🎨) this review with @InLiuOfBulkExps. Check it out!

[Mijin Kim @MijinKim_Lab]

Excited to share our recent rep @J_A_C_S 🎉We find that a full ligand-induced folding transition of supercharged scFv on fluorescent quantum defects induces a substantial local electric change on the defects, shifting the emission energy. Great collab w @Dan_A_Heller @RonaldKoder

[Practical_Fragments @PracticalFrag]

Puzzling out the rules of aggregation. The phenomenon muddies hit-hunting, but could help drug delivery.
@HydroChen2 @HellerLab find patterns that bring it towards rational drug design in @NatureComms
https://t.co/bg5GJkkFij

[Chen Chen @HydroChen2]

Excited to share our latest work @NatureComms! We investigated intermolecular driving forces of small molecule aggregates, commonly observed in high throughput screening and nanoparticle formulation. https://t.co/XZO7TnD39I
Thank you @HellerLab & collabs 👨‍🔬

[Mijin Kim @MijinKim_Lab]

(1/2) Pleased to share our new perspective @NatRevMater 🎉 We discuss knowledge gaps in CNT health and safety concerns and make recommendations to provide R&D and regulatory clarity regarding the material properties of different CNT materials.

[Daniel Heller @Dan_A_Heller]

Our worries over an NGO trying to ban carbon nanotubes prompted lots of work to understand how they could impact humans and the environment. We learned a lot!…. including that one must factor in their potential to help save the environment! https://t.co/BAactTcs0I

[Merav Antman @AntmanMerav]

Celebrating our success in brain lipid detection with carbon nanotube nanosensors! Also, a big shoutout to our hardworking team for their dedication @zviyaari @HydroChen2 , and heartfelt thanks to our incredible mentor @HellerLab
check out our work at https://t.co/odMNsKf5ZE

[Mijin Kim @MijinKim_Lab]

Grateful and humbled to be recognized with prestigious the 2023 #STATWunderkinds!🥰Thanks @HellerLab and the team! Bridging between nanoscience and cancer diagnosis/research will continue at https://t.co/nYkh7rOoSk @GT_CHEM!🔬🧪 #MSKPostdoc

[Mijin Kim @MijinKim_Lab]

We are the September 2023 cover for @NatureRevCancer 🎉
Congrats @HellerLab @magdalinipan @HydroChen2 et Al

[Daniel Heller @Dan_A_Heller]

Highlighted on the cover of @NatureRevCancer - our review on engineering approaches to investigate tumor ecosystems!

[Gianna Stella @ScientistGianna]

Would you erase your failures if you could?

I’m excited to share my perspective on failure as a graduate student. Thank you @ChemBioChem and
@RubenRagg for the opportunity to add to the discussion of destigmatizing failure in academia.

https://t.co/lRcORZNo7f

[Chen Chen @HydroChen2]

Congratulations Mijin! Excited to see the future nano-discoveries emerging from the Kim lab! 🎊🎊

[Mijin Kim @MijinKim_Lab]

(2/2) The Kim lab will develop and implement novel nanobio analytical tools for chembio research and diagnosis. Looking for grad students&postdoc who will grow together! More info will come up soon🧪🔬 Looking forward to work with amazing colleagues and students at Georgia Tech!

[Chen Chen @HydroChen2]

We’re thrilled to share our latest review on biomedical engineering and cancer biology interface! 🎊

[Mijin Kim @MijinKim_Lab]

Delighted to share our Review in @NatureRevCancer🎉
The Review aims to connect the cancer biology and engineering communities to better understand #TME
Pleasure to write with @magdalinipan @HydroChen2 Stephen Ruiz, @KarunaMDPhD @TuomasTammela @HellerLab
https://t.co/hqLXzSUgND

[Chen Chen @HydroChen2]

Very excited to share our new work on in-vivo autophagy sensor technology! Thankful for all the amazing collaborators 🔥🔥

[Mijin Kim @MijinKim_Lab]

(1/2) Just published!😆♥️ We developed a nanosensor technology that quantitatively and dynamically monitors subtle lysosomal hyperacidification events in live cells and in vivo, enabling the transient detection and spatial mapping of autophagy.

https://t.co/A3NbQ0AlHh

[Daniel Heller @Dan_A_Heller]

Thanks to @nchembio and authors Kangqiang Qiu, Zhiqi Tian & Jiajie Diao for this terrific perspective on our work https://t.co/fGNyZ3dAdU

[Gabriella Chua @BetterAtCloning]

“Academic training at every level should take a more people-first approach.” Thank you to @ChemBioChem and @RubenRagg for the opportunity to share our perspective. Below, we call on leaders, admin, and faculty at all institutional levels to help improve the training environment.

[Gabriella Chua @BetterAtCloning]

Loved hearing about some awesome science and enjoying the views here in San Diego!🌞🧬🦠🧫 #BPS2023