@LabDac and I wrote a review: Protein synthesis, degradation, and energy metabolism in T cell immune responses
Been great to really think about #Tcell#Translation#Immunometabolism & what #Proteomics can teach us! Thanks @hongbo_chi for the invite!
1/x
https://t.co/nrb0osQkeX
Very happy to see our latest work out in @emboreports
. Here we discover an unexpected role for IRF3 in STING-induced pro-inflammatory cytokine production: https://t.co/dYAwVHyk0s
Enjoy!
Out today 🙌 new work from the lab in which we show that p53-driven senescence enables phospholipid headgroup recycling to help sustain the increased synthesis of membrane phospholipids of senescent cells https://t.co/SgQoQ3EMUm
New paper in @ClinTransImmuno for PhD student Olivia Moscatelli describing how the whole blood IL-2 assay goes up against the IFN-gamma ELISpot in measuring gluten-specific CD4 T cells in coeliac disease pre and post gluten challenge @WEHI_research
https://t.co/9gvBWBUw8u
This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥
New research: MCL-1 not only prevents cell death, also fuels cells by supporting energy production. Helps explain side effects seen with MCL-1 targeting drugs in cancer clinical trials; could lead to better therapies. In @ScienceMagazine
🔗https://t.co/2Mx4SEc06V
It was great fun to talk about our research on the podcast- Thanks Brenda and Jason! you can hear about our work on #IEL and #LRRK2, a gene mutated in #Crohns and #Parkinsons and how the gut is the most important organ for health :)
📢 World-leading Immunologists. The Nossal Endowed Chair of Immunology has just been announced @WEHI_research. This is your chance to move (or return) to Australia to do ground-breaking research and join a thriving environment for discovery and translation https://t.co/RaXl6V4yN4
Hot off the press! 🔥
In our latest @NatureComms paper, we used in vivo imaging to track EV formation in the bone marrow microenvironment. We found that circulating EVs correlates with tissue damage caused by leukemias like AML!
@WEHI_research@latrobe@AusCellDeathSoc
An excellent opportunity @WEHI_research proteomics facility to join our team. Applications close Friday November 22nd. Please share #teamMassSpec
https://t.co/G99laTyb1T
📢📢the human expansion of ImmPRes is live, with two datasets focussed on human T cells. The raw files for these datasets will be available soon, but we've shared the processed data already.
Want to know what IL2 deprivation does to CD8+ T cells? You know where to look
I'm looking for a postdoc for my lab - Level A or B, full time or part time considered. Working on single cell transcriptomics and spatial data - methods and collaborative analysis. Really excellent compute available ;)
https://t.co/AsaK4psf3t
Excited to see my PhD work out in the world in @embojournal. Thanks to everyone involved - it wouldn’t have possible without you all!
https://t.co/B1b8rmeODG
New from us
In the 2024 Current Opinion in Immunology: Tumour Immunology section, @benjbroom and I contrast the stem-like T cell niche in LN and TME to understand how to enhance vaccination and immunotherapy
Many thanks to @stefanispranger for the invite
https://t.co/qnUnExxEUG
Newly published research from the @MahimaSwamy lab reveals how intestinal immune cells combat Salmonella infection, using specialized killer molecules called Granzymes https://t.co/TKWxMwNukZ @MucosalImmunol
With a mix of pride, enthusiasm, and tremendous relief, I present our latest paper that describes the emergence of atypical epithelial cells in the thymus with age that limit the tissues function at steady-state and its repair after damage… 1/?
https://t.co/DKHWuYeXWf
Two opportunities are available in Proxima Bio, a new spin-out company partially operating at WEHI.
🧪 Protein scientist/Senior protein scientist
https://t.co/VkZ0fQM9EO
🧪Cell biologist/Senior cell biologist
https://t.co/uyonLbLzOz
🗓️ Applications close August 27