Jill Ostrem

Professor UCSF Neurologist-Clinician-Scientist in Deep Brain Stimulation, Expertise in Parkinson's, Dystonia and Tremor

[Jill Ostrem @JillOstremUCSF]

@MichaelOkun Thank you for all you do to spread knowledge and inspire!

[Bob Wachter @Bob_Wachter]

Thrilled that my friend and colleague Andy Josephson will be the next dean of @UCSF School of Medicine. Brilliant clinician, gifted teacher, and one of the warmest people I know – a perfect fit for the moment. Can't wait to work with him in this role.
https://t.co/szEKzkg9XA

[Jill Ostrem @JillOstremUCSF]

Check out Jill Ostrem's fundraising page - https://t.co/8PoTpn2b4p

[DBS Think Tank @DBSThinkTank]

Congratulations to the 6 finalists of the DBS Think Tank Rising Stars Challenge! Tune in Aug 29 at 1pm EST to listen to each finalist present their cutting edge research!

https://t.co/emfIbDc4PG

[Jill Ostrem @JillOstremUCSF]

Check out Jill Ostrem's fundraising page - https://t.co/8PoTpn2b4p

[Nacho Mata @nachogenePD]

I want to give a big shoutout to the incredible @RayDorseyNeuro ! Not only is he a passionate clinician and researcher, but very supportive of young (and not so young 😉) scientists. If you haven’t read this book, you should!
https://t.co/T5HtEWwXev

[Jill Ostrem @JillOstremUCSF]

@MichaelOkun @FixelInstitute @UFHealth Amazing!!! Great photo!!

[Barack Obama @BarackObama]

Don't wait – check your state's voter registration deadline today and make sure you're registered and ready to vote. And then share this with your friends and family so everyone's ready to vote early or by Election Day. https://t.co/jKW0RyeBXC

[Andreas Horn @andreashorn_]

Congratulations to the winners, very well deserved!!

[Michael Okun @MichaelOkun]

When they go low (beta) we go high (gamma) for adaptive DBS for Parkinson's. @littleneuro showing this new @NatureMedicine paper w/ three woman first authors which he is very proud of as three rising stars in the field. @DBSThinkTank first speaker today showing a paper literally just published!

[UC San Francisco @UCSF]

Meet Shawn, a former pro skateboarder diagnosed with Parkinson's nine years ago. With adaptive deep brain stimulation, a personalized algorithm adjusts his treatment as symptoms change. https://t.co/ZwHckhznpM @littleneuro @NeurosurgUCSF

[Carina Oehrn @CarinaOehrn]

The most creative, intense, and rewarding project I’ve ever worked on! Now out @NatureMedicine. Real-world blinded adaptive DBS halves time with motor symptoms and improves quality of life in Parkinson’s disease. With the amazing @scernera1 @LaurenHHammer @littleneuro Philip Starr

[Michael Okun @MichaelOkun]

Can you name primary, secondary and tertiatry prevention strategies for Parkinson's disease? Caitlin Agarwal in @NEJM was the artist for this supplementary figure which is a gem and you should not miss reading and digesting it, as it is hidden in the supplementary information.
Key Points:
- Prevention includes 3 goals – 'primary prevention identifies and removes causes so disease does not develop, secondary prevention identifies the disease processes and intervenes to prevent symptom onset, and tertiary prevention reduces the burden and slows progression in manifest disease.'
- The figure addresses both 'a population perspective and individual perspective.'
- 'Primary prevention involves identifying and removing toxicant chemicals. Education regarding healthy lifestyle, including exercise, diet and sleep applies both to populations and to individuals.'
- 'Screening genetic risks even in the absence of disease-associated change.'
- An opportunity for 'gene-specific interventions.'
- Secondary prevention prevents 'development of manifest disease.' Biomarkers become key.
- Tertiary prevention 'aims to reduce the symptom burden of manifest disease and slow or stop progression.'
My take: We need to shift left from tertiary prevention to secondary and to primary prevention. This should be done concurrently as time is ticking for persons with disease and for persons who will get the disease.
https://t.co/mTmePdVkx4 #Parkinsons @ParkinsonDotOrg @endingpdbook @FixelInstitute

[Jill Ostrem @JillOstremUCSF]

@MichaelOkun @NEJM Thank you for recognizing our work! Proud of you Caitlyn Agarwal!

[Michael Okun @MichaelOkun]

New review paper just out today @NEJM on Parkinson's disease by Professors @JillOstremUCSF and Carlie Tanner @UCSFHospitals. Check out the gems they include like this chart of all the current medication options. I added the 'hot' new article sign as we presented in Aspen @movedisorder this morning. A great read.
https://t.co/aDbsjX1IVv #Parkinsons @ParkinsonDotOrg #fixelinstitute

[UCSF Health @UCSFHospitals]

Video-based machine learning can help clinicians predict motor impairment severity for patients w/ #ParkinsonsDisease, a study finds. The system "could support faster & better diagnostics & treatment in the future.” UCSF’s Dr. Simon Little says. https://t.co/4eTb5kDqJJ

[Michael Okun @MichaelOkun]

Taylor Swift made her debut at her first national neurosurgery meeting in Nashville TN today. Well, these guys wrote this song with her when she was 14. The Warren Brothers and Lee Thomas Miller knocking it out of the park, or should I say hotel ballroom. @taylorswift13 @swiftpage13 @warrenbrothers @LeeThomasMiller

[Andreas Horn @andreashorn_]

🚨#preprint alert 🚨 @Brain_Circuits

GPi DBS for dystonia is effective.

More recently, STN DBS has been investigated, as an alternative.

In what enfolded like a stunning thriller to me, Konstantin Butenko tells a tale of two networks…

https://t.co/1ofANBHjPy

🧵

[Jill Ostrem @JillOstremUCSF]

@DorisWangLab Amazing!!

[Michael Okun @MichaelOkun]

‘The most sacred duty of any leader is to take care of their subordinates.’ We let our Marines down. Caroline Tanner @ucsf with @BrianGrantOrg, Amy Westervelt, Mike Partain and Jerry Ensminger are the heroes leading change and justice for Camp LeJeune victims and also embracing the science that backs up their claims. Parkinson’s, cancer and beyond…#parkinson #cancer #TCE