Delighted to share our work, recently published in @jbiolchem
Check it out here-
Dynamics of interdomain rotation facilitates FtsZ filament assembly - Journal of Biological Chemistry https://t.co/TuCxX4r7Cn
The structural work of my PhD thesis is finally out now as a preprint in Biorxiv. 🤗
Here, we have used cryo-EM and molecular dynamics simulations to understand the basis of curvature in FtsZ protein filament.
https://t.co/SFkGe4zOYE
Prof. BVV Prasad, a DST-VAIBHAV fellow, gave an engaging talk on the "molecular choreography of viral proteins" on the occasion of birth anniversary of a genius scientist Prof. G N Ramachandran. Thank you @Icosahedral16 lab for hosting.
@iitdelhi@sathi_iitdelhi@TSB_Ashoka
Happy to share a part of my PhD work in @TPucadyil lab now online @NatureComms. In collaboration with Joshua Pemberton and Tamas Balla, we show how local production of lipids on #mitochondrial surface regulates the activity of membrane shaping proteins.
https://t.co/LAj5b9rgmv
Disruption of salt bridge interactions in the inter‐domain cleft of the tubulin‐like protein FtsZ of Escherichia coli makes cells sensitive to the cell division inhibitor PC190723 https://t.co/8TiiUwvcKS
The latest JBC cover shows an electron micrograph (background) of FtsZ filaments from Spiroplasma melliferum, a cell wall-less bacteria, and depicts that extended monomers and domain-swapped dimers are incompatible to form filaments.
https://t.co/fHPC8QKvSh #ASBMBJournals
Additionally, the illustration depicts that extended monomers and domain-swapped dimers are incompatible to form filaments, and that monomer addition occurs from the bottom of the filament (center), representing the kinetic polarity of FtsZ filaments.
Delighted to share our work, recently published in @jbiolchem
Check it out here-
Dynamics of interdomain rotation facilitates FtsZ filament assembly - Journal of Biological Chemistry https://t.co/TuCxX4r7Cn