Kabeche Lab

The Kabeche Lab at Yale University is dedicated to uncovering the mechanisms that drive genome instability.

[Yale West Campus @YaleWestCampus]

Congratulations to Lilian Kabeche, faculty member @CancerYale @YaleMBB, who has received @ASCBiology Award for Excellence in Research by an Historically Excluded Person. Read more about Lily's research and mentorship of next gen diverse scientists: https://t.co/7YMm2qwRIw

[Kabeche Lab @KabecheLab]

Congratulations to all the winners (including our awesome leader, Lily!)

[American Society for Cell Biology @ASCBiology]

ASCB is proud to announce the 2024 Honorific Awards! Join us in celebrating the outstanding achievements of our members in research, education, and mentoring. Check out the full list of honorees and their contributions to the life sciences here: https://t.co/SZuKy3MrEO

[Kabeche Lab @KabecheLab]

We’re so grateful to everyone who contributed to this project @Yanshen73854711 @CancerYale and for valuable feedback from the community. Let us know what you think!

[Kabeche Lab @KabecheLab]

Chk(2) out our most recent work! We’re excited to share our discovery about a new mechanism that controls mitotic PLK1 activity: https://t.co/rPYtZutnfA

[Kabeche Lab @KabecheLab]

Although Chk2 and the DNA damage response pathway canonically antagonize mitotic kinases like PLK1 at the G2/M checkpoint, our data shows that this relationship is inverted in mitosis, highlighting how well-characterized interphase signaling pathways can be rewired in mitosis.

[Kabeche Lab @KabecheLab]

Excited to see Elizabeth's presentation at the Cell Cycle Club meeting!

[Robertus de Bruin @DeRobertus]

PROGRAMME
Virtual Cell Cycle Club meeting: Wednesday March 13

3 short talks: Gergely, Mittnacht & @KabecheLab
Breakout session talks
Keynote: @JanSkotheim

Breakout slots still available, deadline this Friday!!

To REGISTER or SUMIT abstract @abcam
https://t.co/5VCr6bFv5Q

[Kabeche Lab @KabecheLab]

Great paper from the Sheltzer lab!

[Jason Sheltzer @JSheltzer]

New from my lab: we show that a clinical-stage oncology drug from Eli Lilly is mischaracterized, and its true anti-cancer target is EGFR.

We also show how in vitro drug assays can be misleading - cellular+genetic methods are needed to determine drug MOAs.

[Kabeche Lab @KabecheLab]

Congratulations @SusanBaserga!! Well deserved!

[Yale Cancer Center @YaleCancer]

Congratulations to Yale Cancer Center members, Dr. Susan Baserga @SusanBaserga and Dr. Emily Wang, on their elections to @theNAMedicine, a prestigious honor!
@SmilowCancer @YaleMed @YNHH @YaleMBB @YaleGenetics @YaleRadOnc @SEICHE_Yale

[Kabeche Lab @KabecheLab]

Our paper is now online! ATR promotes micronuclei rupture and clearance.

[Molecular Cell @MolecularCell]

Online Now: ATR promotes clearance of damaged DNA and damaged cells by rupturing micronuclei https://t.co/kTAEPfcnw5

[Kabeche Lab @KabecheLab]

Great talk by Elizabeth on novel mechanisms of PLK1 regulation at the @YaleMBB retreat!

[Kabeche Lab @KabecheLab]

Great paper by the Simon Lab! @YaleMBB

[Lemmon and Ferguson Labs @LemmonFerguson]

Another Yale West Campus Nature paper:
https://t.co/FymZRO7PxZ
Congrats to the Simon lab and collaborators.

[Kabeche Lab @KabecheLab]

Great publication by the Bleichert lab!

[Bleichert Lab @BleichertLab]

Our latest publication is out now! Check out our paper in @embojournal investigating how ORCA facilitates replication initiation in heterochromatin environments. Congrats to @SahuSumon, Babatunde Ekundayo, and @Ashishk1722 on this team effort!
https://t.co/BguvCVM4yJ

[Kabeche Lab @KabecheLab]

Congratulations Mandar!! 🍾

[Yale Cancer Biology Institute @CancerYale]

Congratulations to #YCBI faculty member Dr. Mandar Muzumdar @MuzumdarLab, for his promotion to Associate Professor! @YaleWestCampus

[Kabeche Lab @KabecheLab]

4-year Lab Anniversary! 🎉 Over the past 4 years, we've changed biological paradigms & published some great papers, obtained 5 grants, presented our work on national and international stages, & created unforgettable memories. Proud of our accomplishments! @YaleMBB @CancerYale

[Kabeche Lab @KabecheLab]

Great job on your STARS end-of-summer presentation, Carla!! @CancerYale @YaleMBB @YaleWestCampus

[Yale West Campus @YaleWestCampus]

“When we identify all the ways a protein works, we can better predict how drugs targeting that protein will affect patients” – Scientists @KabecheLab discover a multi-tasking protein with potential to protect against disease: https://t.co/wGW1FTPtl3

@CellReports @CancerYale

[Kabeche Lab @KabecheLab]

Excited to share our latest work uncovering a novel mechanism by which ATR protects the genome in the absence of DNA damage! @YaleMBB @CancerYale
https://t.co/gJOso9nCWl

[Kabeche Lab @KabecheLab]

To all the fans of cell division in the New England area, there is still time to register for the 2023 BAMM meeting! The free one day meeting will be held @Yale on May 6th. Use the link to check it out and register! https://t.co/56oAACSfY8

[Kabeche Lab @KabecheLab]

#Celldivision fans: check out the 2023 BAMM meeting!! This awesome one day free conference will host an exciting set of speakers from the New England area! This year it will be hosted at @Yale University! Submit a short abstract by April 1st for an opportunity to give a talk.

[Binyam Mogessie ቢንያም ሞገሴ @BinyamMogessie]

Check out this year’s Boston Area Mitosis & Meiosis (BAMM!) meeting @KabecheLab (Yale), Dan Needleman (Harvard) and I are organizing. Please spread the word and register for a day of exciting cell division biology on May 6, 2023 at Yale. https://t.co/3P02sUf4pK