Kay Choi lab

Structural Virology lab, BMB, UTMB & MCB, IU. Viral replication & infection machinery, RNA structure, X-ray crystallography, cryo-electron microscopy

[Kay Choi lab @KayChoi_lab]

How does enterovirus protease specifically recognize its viral RNA genome?

Hint: It takes two!
Happy to share our publication in @ScienceAdvances

Structure of coxsackievirus cloverleaf RNA and 3C protease dimer establishes its RNA-binding mechanism
https://t.co/dSZwFouCv8

[NatureStructMolBiol @NatureSMB]

We are hiring a new editor! If you want to join the Nature Structural & Molecular Biology team and help publish exciting research, please apply. Deadline is June 20th. More information here: https://t.co/FmHwaopNOh

[Kay Choi lab @KayChoi_lab]

Post-doc position is available in Choi laboratory at IU. Our research focuses on the structure and function of viral RNAs and replication. Experience in biochemistry or structural biology (X-ray crystallography & cryo-EM) is required. Please apply to [email protected]

Please RT.

[mcmorais lab @mcmoraislab]

This post is a little late, but the mcmorais lab is happy to announce our recent review on the mechanochemistry of virus dsDNA packaging motors:

https://t.co/TxXVEb6lHe

Congratulations to my co-authors Josh Pajak, Nikolai Prokhorov, and Paul Jardine

[Kay Choi lab @KayChoi_lab]

@mcmoraislab Congratulations Mike and Marc!

[mcmorais lab @mcmoraislab]

Check out a new pub from the mcmorais lab on the role of bacteriophage scaffold proteins in the self-assembly and maturation of virus capsids:

https://t.co/QPRsmYrFbE

This work was largely driven by my former colleague at UTMB Mike Woodson.

[shee-mei lok @LokShee]

Want to attend the HCV-Flavi symposium and also to visit the beautiful Singapore? #flavivirus #dengue #zika #arbovirus https://t.co/LXA4Iky90A

[IU Biology @IUBiology]

IU biology professor Tuli Mukhopadhyay was awarded the 2025 Alice C. Evans Award for Advancement of Women, which recognizes outstanding contributions toward the full participation and advancement of women in microbial sciences. Read more: https://t.co/wrC4zylv6Y

[Jeremy Farrar @JeremyFarrar]

Dengue fever: a record 12.4m cases in 2024 so far (an underestimate) what is driving world’s largest outbreak? Worth putting into context role & effectiveness fogging as mosquito control measure for dengue? The image is dramatic & always used,it’s utility? https://t.co/qKzznYF6hT

[Nikos Vasilakis @Vasilakis_Lab]

Sustainable investment in basic research is critical. It leads to transformative and sometimes disruptive to the status quo outcomes that improve our lives. https://t.co/IxlCP0vJAp. @ASTMH @utmbnews @ihii_utmb @sbviro @AmerSocVirol @Virology_FAMERP @create_neo @Rossi_viruslab

[Joseph Wang @VirusEMLab]

Meeting starts soon! Registration ends in 2 days for the Virus Structure and Assembly Conference. See you all in less than a week!😎

[Kay Choi lab @KayChoi_lab]

Congratulations to graduate student @jerrichotipo for winning a poster prize @RNASociety meeting!

[Kay Choi lab @KayChoi_lab]

Small compounds can distinguish the different RNA bulges in Zika virus stem-loop A for binding.

Don't forget to read the meet the first author section at the end!

[RNA @RNAJournal]

Flexible bulge structures of Zika virus SLA RNA bind small molecules differently, offering potential for exploitation in fragment-based drug discovery. #RNA #science #structuralbiology #Zika #drugdiscovery @KayChoi_lab @jerrichotipo https://t.co/7fjWgIC9kf

[RNA @RNAJournal]

Flexible bulge structures of Zika virus SLA RNA bind small molecules differently, offering potential for exploitation in fragment-based drug discovery. #RNA #science #structuralbiology #Zika #drugdiscovery @KayChoi_lab @jerrichotipo https://t.co/7fjWgIC9kf

[Kay Choi lab @KayChoi_lab]

If you are @RNASociety meeting, check out our posters on RNA structures of HIV Rev response element (RRE)!

@jerrichotipo on Thursday P2-#405
Keerthi Gottipati on Friday P3-#635

#RNA #RNAstructure #HIV

[Kay Choi lab @KayChoi_lab]

Happy to share our new paper on HIV Rev response element (RRE) @NatureComms. Congratulations @jerrichotipo and Keerthi Gottipati.

Structure of HIV-1 RRE stem-loop II identifies two conformational states of the high-affinity Rev binding site
https://t.co/rJ8G3exiNO

[FASEB @FASEBorg]

Your viral findings could go "viral" at this conference serving researchers since 1990. Join speakers Paula Traktman and Peter Kwong alongside #VSASRC organizers @jurcortines, @GinoCingolani2, @VirusEMLab and more. View the agenda and save your space: https://t.co/ilNhKoWwyX

[Science Magazine @ScienceMagazine]

Women leave academia at higher rates than men at every career stage, and attrition is especially high among three groups: tenured faculty, women in non-STEM fields, and women employed at less prestigious institutions, a @ScienceAdvances analysis finds. https://t.co/5vw7yGYDMi

[Jake McKinlay @JakeMcKinlay]

We are hiring faculty at the associate and full professor level in Synthetic Biology. Come join us at Indiana University's beautiful Bloomington campus. https://t.co/JgIh2xVEQd

[Kay Choi lab @KayChoi_lab]

I am very sorry to hear this. His love for virus and sense of humor will be greatly missed.

[Dr. ᐯᗩᒪEᖇIE ᕼOᖇᔕᒪEY 🔬 @ValerieJHorsley]

My dear friend @BrettLindenbach passed away on Saturday morning. Hug your loved ones and show up for people in your life. That’s all that matters. https://t.co/olRtC1Sw2n