Keith Siew

BSc (Hons), MSc, PhD in Medicine #FirstGen | Physiologist-Pharmacogist & Microscopist | Me: 🇮🇪👨‍🔬🏳️‍🌈 he/him | Work: 🔬💊🐀⚕️ 🧪🧬 @LTubularCentre

[Keith Siew @KeithSiew]

@lalarukhharis @paulg Also proximity to some cool stuff like NASA, other big research institutes, nice weather and always something on in the city!

[Mendra @MendraInc]

Today, we’re launching Mendra, a rare disease therapeutics company enabled by AI.

We’re announcing an oversubscribed $82M Series A co-led by @OrbiMed, @8vc, and @5amVentures with participation from @Lux_Capital and @Wing_VC.

Full announcement 👇
https://t.co/rjxxWMa3Nu

[Keith Siew @KeithSiew]

Very proud and super excited to see you push new boundaries and make a change to those living with rare diseases!

[Lalarukh Haris Shaikh @lalarukhharis]

Ten years ago, I joined @PalantirTech because the problems felt impossible to ignore. Deploying software for mission-critical systems in life sciences and aerospace where failure wasn’t abstract. That weight shaped how I think about work.

I’m bringing that same weight to something new.

Today, we’re announcing @MendraInc with $82 million to acquire, develop, and commercialize therapies for rare diseases. These conditions affect millions of people, yet most still have no approved treatment and are often undiagnosed or misdiagnosed. Many of these conditions present in childhood.

Becoming a parent made this personal. It sharpened the stakes. Rare disease development and commercialization is a systems problem. Advances in data orchestration and AI now make it possible to identify patients and accelerate delivery of therapeutics in ways that simply weren’t feasible years ago.

Immensely grateful to my Palantir family for the last decade, and to the team I’m building with at @MendraInc. Let’s go!

[LinkGevity @LinkGevity]

Great interview on our exciting #aging intervention by @CarinaCarlaKern @KeithSiew! #longevity #innovation #biotech

[Keith Siew @KeithSiew]

Thanks again to @NASAGeneLab and all the co-authors for all their incredible work. It was a pleasure to be involved with the work, major props the joint first authors, Rebecca Finch and Geraldine Vitry, and of course the Senior PI, Willian da Silveira.

@RenalUCL @ucl @SalfordUni

[London Tubular Centre @LTubularCentre]

Check our latest paper on the mouse strain-specific spaceflight-induced changes in kidney gene expression after flying🚀 to the ISS🛰️.

https://t.co/FhN65IUpFx

[Ryan T. Scott @RyanTScott]

New API 🎉 for all omics, phenotypic, imaging, physiological, biomedical, and behavioral data in the NASA Open Science Data Repository 🎉

[Chris Mason @mason_lab]

Thanks @politico for interview and coverage about our plan for long-duration missions and new biological twin/iPSC studies: https://t.co/i8yzqmh6nI

[London Tubular Centre @LTubularCentre]

Check out @KeithSiew on @theldnstandard
#TheStandard #TechScienceDaily Podcast talking about the health consequences of #spaceflight and what an #AstronautsReturn can expect to do recover their health.

https://t.co/rXvTWqWiWt

[Keith Siew @KeithSiew]

Thanks to @rhiannon_hopley for having me on the 6:30pm @itvnews last night to make a short appearance about the impacts of #spaceflight on #AstronautsReturn.

@RenalUCL @LTubularCentre @ucl @spacegovuk @NASA

[The Federal @TheFederal_News]

LIVE | After 9 months aboard the #ISS, astronauts #SunitaWilliams and #ButchWilmore return to Earth! What challenges await? | @srinitvtn | @nishapsekar

WATCH: https://t.co/OPkod9WeZr

[Afshin Beheshti @AfshinBeheshti]

I, along with @mason_lab, were interviewed in the latest Salon news article on the impact of prolonged space missions.
Check out the full article here: https://t.co/qeDi8sZK7L
@PittResearch
#SpaceBiomedicine #AstronautHealth #Microgravity #Mitochondria

[Keith Siew @KeithSiew]

Just out: @ExpPhysiol Editorial by @CarinaCarlaKern and I on the opportunities for innovation in space biology research.

Also checkout our keynote panel with @DamianMBaileyEP on this topic at @SpaceCommExpo Wed 12th March:
https://t.co/FCYRAPVx6J

@LinkGevity
@RenalUCL
@ucl

[Dr Carina Kern @CarinaCarlaKern]

📢Read our latest paper in the #Journal of Experimental Physiology🚀“Beyond the #horizon: Why #space biology is the next great #innovation opportunity” 🚀🧬🧬

🔗 https://t.co/FtQmvJfhwx

📖 co-authored by Dr @KeithSiew (@ucl)

@BabrahamUK @LinkGevity

[London Tubular Centre @LTubularCentre]

🚨Booking Open🚨
UCL’s Applied Renal Physiology Course (14-16 May 2025) is now open for registration!
🔑 3 days of learning on electrolyte imbalances, hypertension, and fluid management.
🎓 2 Bursaries Available!
💸 Early Bird – Book by 28th Feb!
🔗 Book: https://t.co/RuJH1SJnDV

[Keith Siew @KeithSiew]

@NimaxTheatres I've received no link with a code for the presale for Hadestown?

[Ryan T. Scott @RyanTScott]

YouTube Interview w/@KeithSiew regarding this @NatureComms article:

🔗https://t.co/K14PYFYYwZ

[Ryan T. Scott @RyanTScott]

Yay NASA’s Open Science Data Repository 🎉Data, metadata, standards, tools, community, publications, trainings are in new database paper in @NAR_Open 🚀 @NASAGeneLab @NASASpaceSci @mason_lab @atulbutte @cyrilzakka @moorejh @DrChrisCombs @AfshinBeheshti

🔗https://t.co/jInbI11bHl

[NASA GeneLab @NASAGeneLab]

📣 Enjoy hearing Dr Siew's Open Science journey that lets you find out why he ends his interview by saying "Free samples, free data: What's not to like?" in this #OSDR Success Stories interview. #SOMA #kidney #SpaceBiology #OpenScience

🎙️ https://t.co/dWkFbM8YJ3

[Ryan T. Scott @RyanTScott]

🚀 @KeithSiew @LTubularCentre @physoc @NatureComms
🔗 Siew, K. et al. Cosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction. Nat Commun 2024. https://t.co/K14PYFYqHr

[Keith Siew @KeithSiew]

Delighted to have been highlighted by @NASAGeneLab as one of the #OSDR success stories for 2024. It's been a huge joy and pleasure to get to know so many wonderful people in the space health research community. Check out the links:
https://t.co/2B6sfZHurj
https://t.co/AULgGsvHtD