Ujjwal Kumar, Ph.D

Postdoctoral Associate, Duke Human Vaccine Institute, USA
#Antibodies #Viruses #Crystallography #immunology#Cryo-EM

[Ujjwal Kumar, Ph.D @Kumar___Ujjwal]

Vaccination can induce broadly cross-neutralizing antibodies targeting the HIV-1 Env apex.
A key step toward neutralizing Tier 2, clinically relevant viruses.
#HIVResearch #Vaccines
https://t.co/2pCJCsPtsJ

[Ujjwal Kumar, Ph.D @Kumar___Ujjwal]

Attended the DCHSB (Duke Center for HIV Structural Biology) 2026 meeting at Duke.
Great discussions on HIV-1 structural biology and Env dynamics.Grateful to Dr. Priyamvada Acharya for organizing.
#DCHSB2026 #HIVResearch

[Ruslan Rust @rust_ruslan]

Eleven clinical trials that will shape medicine in 2026

Happy to see a lot of cell-based therapies!

https://t.co/23fKXbbp11

[Ujjwal Kumar, Ph.D @Kumar___Ujjwal]

The evolution of cryo-electron microscopy (cryo-EM) from Ceta-F CMOS camera to Falcon C detector represents a significant advancement.

[Priyamvada Acharya @PriyamvadaA_Lab]

Check out our paper “An integrated workflow for structural virology with a 100 keV electron microscope” on @biorxivpreprint

@DukeHIVStrucBio @TheDHVI @dukebiochem @DukeMedSchool @DukeSurgery @DukeU

https://t.co/Srt3FcX7dW

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

[Ujjwal Kumar, Ph.D @Kumar___Ujjwal]

When someone says that your biological genome was created by #AI, and that's why your functional role is so advanced. It's quite fascinating, though, but not in this AI era.

https://t.co/IxnuGcR50m

doi: https://t.co/s5YGAthsey

[Martin Pacesa @MartinPacesa]

Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, @csche11h, @sokrypton, @befcorreia and many other amazing lab members and collaborators.

https://t.co/PTMoqQqwcU

[Julia Bauman @JuliaBauman2]

The most radically recoded genome yet!

Syn57 is E Coli with only 57 codons, freeing space to encode up to 4 non-canonical amino acids. That, combined with its virus resistance, will make it an incredible tool for biomanufacturing.

From the Chin Lab in @ScienceMagazine

[Itai Yanai @ItaiYanai]

'Night science' is what you do when you're not sure what's the question.

[Ujjwal Kumar, Ph.D @Kumar___Ujjwal]

Astonishing nature view from the lab window. 🧊❄️❄️❄️⛄️⛄️🌨🌨☃️☃️
#Lab #research #Nature #wonderful

[Priyamvada Acharya @PriyamvadaA_Lab]

@DukeHIVStrucBio is at the @BiophysicalSoc Annual Meeting. #BPS2025

[Priyamvada Acharya @PriyamvadaA_Lab]

New preprint from the lab out on "Structural and antigenic characterization of novel and diverse Henipavirus glycoproteins" https://t.co/u5EPCiDy3n

[Ujjwal Kumar, Ph.D @Kumar___Ujjwal]

It represents the variety of #Cultures, #Languages, #Foods, #Homelands, #Colors #Destinations #Biodiversities #Values and we live together, work together, and think together for a better and healthier life for human beings #Rasangi #Xaio #Victor #Emma #Research #HIV #Strcuture

[Ujjwal Kumar, Ph.D @Kumar___Ujjwal]

The winner of #DHVI Reindeer Game 2024 is 🥳 🎉 🎅 🥳🎉 🥳 🎉 🎅 🥳 #Pro_Peptides (#AcharyaLab). 🎉 🥳
This photo-selfie is not just a winning team photo. It's more than that like Human Happiness beyond the horizon.
@TheDHVI @DukeHIVStrucBio @DukeMedSchool @PriyamvadaA_Lab

[BRIC-NII @NImmunology]

A new study from Dr. Sarika’s Lab at @NImmunology reports that ARL6IP5 induces reticulophagy to reduce ER stress as well as unfolded & misfolded proteins.
A potential therapeutic approach for combating prion disease!
📰in #Autophagy @tandfonline
Read here🔗https://t.co/u6WRZgjCX7

[Ujjwal Kumar, Ph.D @Kumar___Ujjwal]

degraded in the lysosomes.
Congratulation Team

[Ujjwal Kumar, Ph.D @Kumar___Ujjwal]

The ARL6IP protein is a transmembrane (TM) protein with four TM domains and two soluble domains (N-terminal or C-terminal). The structure of ARL6IP is quite complex due to the high mobility in local region domains. It seems that it would be playing interchangeable forms from

[Kajal Kamble @Kajal__Kamble]

Excited to share my Ph.D. work, "A novel ER stress regulator ARL6IP5 induces reticulophagy to ameliorate the prion burden," now published in @Autophagy journal! 🎉✨
https://t.co/8BakDnsPTT

#Neurodegeneration #PrionDisease #Autophagy #Reticulophagy #ERStres #WomenInAutophagy

[Ujjwal Kumar, Ph.D @Kumar___Ujjwal]

maintain ER quality and function. This protein is also highly dynamic in nature in the ER. Interestingly, this study revealed that it interacts with one of the CALCOCO1 domains (a soluble reticulophagy receptor) and helps guide unfolded and misfolded (prion-like) proteins to be

[Kajal Kamble @Kajal__Kamble]

Excited to share my Ph.D. work, "A novel ER stress regulator ARL6IP5 induces reticulophagy to ameliorate the prion burden," now published in @Autophagy journal! 🎉✨
https://t.co/8BakDnsPTT

#Neurodegeneration #PrionDisease #Autophagy #Reticulophagy #ERStres #WomenInAutophagy