How does caloric restriction reduce energy expenditure while preserving energy storage?
https://t.co/T8EZ3a18c2
Alan R. Saltiel @LabSaltiel & team @UCSanDiego show TBK1 acts as a brake on fat burning during fasting—and the combination of a TBK1 inhibitor and an AMPK activator reverses obesity and improves #MetabolicHealth in mice.
The figure: Combined TBK1 inhibition and AMPK activation improve metabolic health in obese mice.
Tomorrow (5/12), join us for the 2026 Saltiel Life Sciences Symposium: Decoding #GLP1s.
View the full schedule, including a poster session featuring U-M research:
https://t.co/hJvwBu02hy
Dr. Irfan Lodhi and collaborators identified a pathway that regulates how the body breaks down fat during metabolic stress, including severe illness and cachexia, revealing insight into how stable fat stores are mobilized under stress conditions. https://t.co/uhCGEJUC4V
UC San Diego Professor Elected to American Academy of Arts https://t.co/h8DXpjUKYs
As several of my friends have commented, standards seem to have slipped.
Join us May 12 for the 2026 Saltiel Life Sciences Syposium: Decoding GLP-1s!
This full-day event will explore the fundamental cellular mechanisms behind the new generation of hashtag#GLP1 therapeutics, as well as ongoing efforts to improve them.
Speakers include @AmberAlhadeff, @DanielJDrucker, @TimoMueller_IDO, Martin Myers, @tunepers , @seeleyrj and @thewilliamslab
With great sadness I report the passing of my scientific mentor Jesse Roth at age 91. Jesse was a brilliant & innovative scientist who led the field of membrane receptor biology from NIH diabetes branch. A small part of that family tree is shown. May his memory be a blessing.
Meet the sixteen ASBMB members who were recognized for exceptional service and scientific impact across research, education, mentorship, outreach and leadership!
https://t.co/dKacsT3oFD
#ASBMBMemberNews#Biochemistry#MolecularBiology#ASBMBFellows
Meet the 2026 ASBMB Fellows
Sixteen members were recognized for exceptional service and scientific impact across research, education, mentorship, outreach and leadership.
Join us in celebrating them at #ASBMB26!
➡️ Learn more about the 2026 fellows: https://t.co/dKacsT3oFD.
Today’s 📰#JEMjc@JExpMed highlights the work of
@LabSaltiel@UCSDMedSchool@Nature reporting the role of neutrophil-derived IL-1β in preserving lipid stores during metabolic stress.
https://t.co/dv19Sp0yBb
Happy to share our paper is now published in @NatureComms. This work studies transcriptional regulation of glycogen metabolism genes in adipocytes. Grateful to my mentor @LabSaltiel and all collaborators for their guidance and support. https://t.co/QCpdRlsyZ3
Happy to share our paper is now published in @NatureComms. This work studies transcriptional regulation of glycogen metabolism genes in adipocytes. Grateful to my mentor @LabSaltiel and all collaborators for their guidance and support. https://t.co/QCpdRlsyZ3
#NASmember Pedro Cuatrecasas devoted himself to improving human health, overseeing the development of 40+ new drugs across his career. Read about his work as a scientific innovator and leader in pharmaceutical discovery in a new memoir: https://t.co/Ug9zuGLi5K #MemoirMonday
@LabSpiegelman Guess they were commemorating the discovery and development of MEK inhibitors with a picture from the same era. Wait- are you saying I've aged?