Laetitia Largeaud

Medical biologist PharmD, PhD. Associate Professor @CHUToulouse. Passionate about #hematology #immunology hematopoietic stem cell #GATA2 🏔🎿

[Guillaume P. Andrieu @GuillaumeInALab]

It’s CHO-time! Looking forward to meeting you all there!

[nature @Nature]

A map of mouse development from conception to birth tracks 12.4 million cells at single-cell resolution as they mature into organs and other tissues https://t.co/MWPMXeLJo9

[Peggy Goodell @Goodell_Lab]

📢 Happy to announce our new review on stem cell #aging! We integrate traditional concepts/hallmarks of aging with emerging data on somatic evolution and stem cell competition. @NatureAging

https://t.co/3mbNNMzNkk

[Giorgetti Lab @HeSteCBio]

🔬Job Opportunity Alert!🌟
Join our team as a Bioinformatician. If you're passionate about unraveling genomic mysteries and decoding biological data in blood disorders, this role is for you! Apply now! Deadline: 25/02/24 #Bioinformatics #ResearchJobs🧬💻

https://t.co/yWWs6CiFqp

[Giorgetti Lab @HeSteCBio]

Position still open!! Don’t miss the opportunity to join us! #GATA2 #CRISPR #StemCell

[Livius Penter @livius_tacitus]

👋 Hello 2024 - introducing nanoranger! 🐍

Are we ready to use @nanopore for tracking clonal evolution with #singlecell #genomics❓

Our manuscript provides vignettes on how, for example by tracking #AML during #immunotherapy

🔥🔥🔥
@NatureComms
https://t.co/om6U0KsS9a

👇1/

[Casanova Lab @casanova_lab]

1/ 🔉Our lab is looking for two energetic and enthusiastic #postdocs 👩‍🔬🧑‍🔬 to study the causes and consequences of auto-Abs to type I IFNs (https://t.co/LKopzuccFT). If you are interested, please write to [email protected] 📧 .

[Stéphane Mancini @StephaneMancini]

Delighted to see the latest article leaded by ⁦@BastienGerby⁩ at ⁦@crctoncopole⁩ out in ⁦@JExpMed⁩ today. Glad to be part of this fruitful long term collaboration! More to come soon I hope 🤞 https://t.co/9mzgW14imw

[Jamie Blundell @jrblundell]

For anyone at #ASHG2023 check out our recent work led by superstar student @hamish_macg on modelling the deceleration of clonal haem in #UKBB. Cancer poster session III Saturday AM. Evidence of age-related slow down in HSC dynamics.

[Laetitia Largeaud @LargeaudLaet]

Very happy to have taken part in the 10th International symposium on MDS and SAA in Childhood in Lisbon 🇵🇹 with @marlene_pasquet . We are looking forward to seeing all the enthusiasts of these themes again soon. #gata2deficiency #iBMF #pediatricMDS
Thanks to the organizers #EWOG

[Caroline Watson @carolinewatson]

📢Clonal hematopoiesis driven by mCAs📢What fitness effects do mCAs confer to our blood cells?🩸 How often do they occur? Does an mCA’s fitness correlate with blood cancer risk?🔎Read mine & @jrblundell's latest paper @NatureGenet to find out (& more!):👉🔗https://t.co/DHxxlYXX2z

[Laetitia Largeaud @LargeaudLaet]

@GuillaumeInALab @DoctorDianaP In the sky!!!

[Laetitia Largeaud @LargeaudLaet]

@DelabesseTeam @marlene_pasquet @CyrilBroccardo

[Laetitia Largeaud @LargeaudLaet]

We are delighted to present our pre-print on the consequences of the GATA2 R396Q germline mutation on the hematopoietic stem cell compartment.
From embryogenesis to aging, this mutation quantitatively and functionally impacts HSPCs. 👉

[bioRxiv @biorxivpreprint]

Loss of HSC stemness identity is associated with exhaustion and hyporesponsiveness in GATA2 deficiency syndrome https://t.co/8o8yUxcGT4 #bioRxiv

[Kellie Machlus @theclotthickens]

Today, we get to see IN PRINT what happens when the beauty of megakaryocytes and the brilliance of @nubama combine
I could not be more excited to share our publication, revealing that both MK maturation and platelet production rely on membrane PUFAs. 🧵👇
https://t.co/QlcwsF6ZZ3

[Jennifer Trowbridge @TrowbridgeLab]

📢 Roll out the red carpet for our newest #bioRxiv preprint “Oncostatin M is a Master Regulator of an Inflammatory Network in Dnmt3a-Mutant Hematopoietic Stem Cells” by lead author & fantastic @TuftsGSBS PhD student @Logan_Schwartz1 🙌 1/n https://t.co/A4Pl8Affsr

[CRCT-Oncopole @crctoncopole]

Labellisation Ligue Contre le Cancer de l'équipe IGAALD du @crctoncopole pendant 5 ans
➡️https://t.co/aqeN97PBuO

[UNICORN Hemato @UNICORN_Hemato]

🦄📣 Calling all blood-pumping enthusiasts! Join our running group of hematologists! You’re an RBC (Running Blood Cell) or a WBC (Wickedly Balanced Crawler)? There is a pace for everyone to run the extra mile together! #HematologyOnTheMove 🩸🏃‍♀️🏃‍♂️ Join here https://t.co/VUL3xHdwhz

[Meng Wang @DrMengWang]

What causes #ageing to our blood🩸?

Read our latest study @MolecularCell showing 🧬 DNA damage from aldehyde metabolites drive blood stem cell ageing via a p53 response.
https://t.co/Xt92gXt609

Wonderful collaboration of @ketanpatelimmo1 and @BertieGottgens labs! More below:

[Sébastien Couraud 🫁🚭🌍 @s_couraud]

Très heureux de clôturer, sous notre beau soleil sudiste, la 8eme promotion du DU de pédagogie médicale de @UnivLyon1 !