Jaemin Lee

Associate Professor, Aging, Metabolism and Physiology Laboratory at DGIST, Korea
@DGIST_KOREA

[Jaemin Lee @LeeFormica73]

:(

[MedPage Today @medpagetoday]

🚨🗣️⬇️BREAKING: Members of @AmDiabetesAssn were escorted by police out of the convention center in New Orleans during the organization's annual meeting on Friday as they handed out copies of an editorial criticizing Trump administration changes to U.S. biomedical research.

[Eric Topol @EricTopol]

Retatrutide, a triple receptor drug for GLP-1, GIP, and glucagon, is the most powerful weight loss drug yet. A significant issue is too much weight loss among the trial participants. New randomized trial results announced today with 28% body weight loss.
gift link https://t.co/82tRkOvQ49

[Eric Topol @EricTopol]

New @Nature
A quintuple [GLP-1 + 4 other] receptor agonist drug that exceeds effects of the dual receptor (GLP-1 and GIP, tirzepatide) in the experimental model vs diabetes and obesity
(in case you thought a dual receptor was max effect, as also seen with retatrutide, a triple receptor agonist)
https://t.co/kqkNJ7My4B

[Jaemin Lee @LeeFormica73]

Retrosplenial cortex vulnerability links severe hypoglycemia to cognitive impairment through neuron–microglia crosstalk https://t.co/Ef9jGnDWe0

[NEJM @NEJM]

GLP-1 receptor agonists are increasingly used to treat type 2 diabetes and obesity, and trials have shown reductions in cardiovascular risk and slowing of kidney failure. Adverse events are mostly gastrointestinal. Read the full review: https://t.co/SNdSrVXqWJ

[Jaemin Lee @LeeFormica73]

In our latest preprint, we reveal that the ubiquitin ligase Cereblon (CRBN) acts as a critical regulator of SIM1 in the hypothalamus.

Check out our study on how this interaction drives central obesity: https://t.co/vsFUdWEd93

[Nature Medicine @NatureMedicine]

Researchers studied blood-based metabolome of over 23,000 individuals from 10 ethnically diverse cohorts. They identified 235 metabolites associated with future risk of T2D. By integrating genetic and modifiable lifestyle factors, their findings provide insights into T2D mechanisms and could improve risk prediction and inform precision prevention.
https://t.co/PnxC8YUgEW

[Eric Topol @EricTopol]

The gastrointestinal side effects of GLP-1 drugs are mediated by the brain, not the gut. The gut-brain axis at work @jclinicalinvest
https://t.co/8meow41j83

[Jaemin Lee @LeeFormica73]

@LodhiLab @Nature @Jessielxj2 @WashUDeptMed Great work! Congrats!

[Jaemin Lee @LeeFormica73]

https://t.co/qIMknkbRha

[Jaemin Lee @LeeFormica73]

Nice review paper by Hyung Jin Choi at SNU published in DMJ - GLP-1 and hypothalamic regulation of satiation https://t.co/BVL6Rmbp6k

[Islet Research Seminar Series @IsletSeries]

Join us this Thursday 5/15 for Lori Sussel's seminar on islet RNA processing

[Jaemin Lee @LeeFormica73]

Insulin molecule can sense blood glucose levels! ‘Smart’ insulin prevents diabetic highs — and deadly lows https://t.co/Vx1egMg1zf

[Young Hee Lee @SerenaYounghee]

Happy to annonce new paper im our lab. Brilliant work !! I am very proud of @kyusik_kim_ @mattty0514 @HyungJinChoiSNU and all authors !! :)

[Jaemin Lee @LeeFormica73]

Congrats for Hyung Jin's group for this awesome works!!!

[Jaemin Lee @LeeFormica73]

The research groups of Hyung Jin Choi @ Seoul National University and Kevin Williams @ UT Southwestern found that DMH GLP-1R neurons mediate the feeling of fullness before actual eating.

[Daniel J Drucker @DanielJDrucker]

How does GLP-1 promote satiety, leading to #weightloss Some new insights https://t.co/PJJgBk32YW

[Daniel J Drucker @DanielJDrucker]

A ranking of commonly used #MASLD models, based on their proximity to human MASLD, @NatMetabolism https://t.co/5xDCTRHSyr

[Daniel J Drucker @DanielJDrucker]

dLS-GLP-1R neurons and the inhibitory pathway to LHA can regulate feeding behavior, which might serve as a potential therapeutic target for the treatment of eating disorders or #obesity @MolMetab https://t.co/cfkgCnhH6k

[Jaemin Lee @LeeFormica73]

Three excellent speakers (Umut Ozcan, Matthias Tschop, Robert Kushner) on anti-obesity treatment using pharmacological way at JDS, Tokyo, Japan