@CircRes May 9th Issue is Out! https://t.co/IiX6g6rOKd
Cover: Representative IF staining of endothelial cells (magenta), inflammation (yellow), & WGA (green) in a 4-chamber view of a heart 7 days after Echocardiography-Guided Induction of I/R;nuclei-blue.
scRNA-Seq profiling of 🫀interstitial cells reveals fibrosis in HFpEF to be distinct from HFrEF including the induction of basement membrane collagens and a protective ⬆️ of ANGPTL4 in murine and human HFpEF | led by @LauraWienecke and @jan_lanzer
https://t.co/DgALDoP5Zn
What do Angptl4 and collagen IV have to do with fibrosis in HFpEF?🫀 Proud to have found some answers!🔬 Thanks to my co-first @jan_lanzer, all authors and our supervisor team for excellent support @LeuschnerLab@JulioSaezRod 👌🏻 https://t.co/OMUSJZ3hQU
Check out our paper just published in Circulation
➡️ Translation controls inflammation after myocardial infarction
https://t.co/xWORVd0MKd
This work was a huge collaborative effort over many years.
@dzhk_germany@DGK_org@VolkersMirko
Key findings + paper summary below 🧵⬇️⬇️⬇️
Read my Tools of the Trade article, published in @NatRevCardiol, highlighting my experience with and the method of ultrasound guided induction of myocardial infarction:
https://t.co/GNFn4rSA3L
Thanks to @FloSicklinger & F. Leuschner for developing such an innovative method.
A shortcut to the infarcted heart
Excited to share our collaborative effort with @DenisSchapiro lab led by @FloSicklinger and @FloWuenne. Using spatial omics technologies, we found a new way how monocytes sneak into the infarcted heart.
https://t.co/cOO80X7L9M